Literature DB >> 2268504

Contractions to 5-hydroxytryptamine in human coronary artery and human saphenous vein.

M Borton1, M Neligan, F Wood, P Dervan, K Goggins, J R Docherty.   

Abstract

Isometric contractions were obtained to 5-hydroxytryptamine receptor agonists in human saphenous vein and human coronary artery. Based on the interaction with the 5-HT2 receptor antagonist ketanserin, both 5-HT1 and 5-HT2 receptors are involved in contractions of human saphenous vein, but the predominant subtype involved in contractions of human coronary artery is the 5-HT1 receptor.

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Year:  1990        PMID： 2268504      PMCID： PMC1368106          DOI： 10.1111/j.1365-2125.1990.tb05476.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  5 in total

1.  Comparison of serotonergic receptor subtypes on the smooth muscle and endothelium of the canine coronary artery.

Authors:  D S Houston; P M Vanhoutte
Journal:  J Pharmacol Exp Ther       Date:  1988-01       Impact factor: 4.030

2.  An examination of 5-hydroxytryptamine receptors in human saphenous vein.

Authors:  J R Docherty; L Hyland
Journal:  Br J Pharmacol       Date:  1986-09       Impact factor: 8.739

Review 3.  Vascular serotonin receptors. Correlation with 5-HT1 and 5-HT2 binding sites.

Authors:  S J Peroutka
Journal:  Biochem Pharmacol       Date:  1984-08-01       Impact factor: 5.858

4.  5-Hydroxytryptamine contracts human coronary arteries predominantly via 5-HT2 receptor activation.

Authors:  H E Connor; W Feniuk; P P Humphrey
Journal:  Eur J Pharmacol       Date:  1989-02-14       Impact factor: 4.432

5.  A comparison of 5-hydroxytryptamine receptors mediating contraction in rabbit aorta and dog saphenous vein: evidence for different receptor types obtained by use of selective agonists and antagonists.

Authors:  W Feniuk; P P Humphrey; M J Perren; A D Watts
Journal:  Br J Pharmacol       Date:  1985-11       Impact factor: 8.739
  5 in total
  3 in total

Review 1.  Serotonin and blood pressure regulation.

Authors:  Stephanie W Watts; Shaun F Morrison; Robert Patrick Davis; Susan M Barman
Journal:  Pharmacol Rev       Date:  2012-03-08       Impact factor: 25.468

Review 2.  Clinical pharmacology, physiology and pathophysiology of superficial veins--2.

Authors:  W H Aellig
Journal:  Br J Clin Pharmacol       Date:  1994-10       Impact factor: 4.335

3.  Cloning and functional characterization of the rat stomach fundus serotonin receptor.

Authors:  M Foguet; D Hoyer; L A Pardo; A Parekh; F W Kluxen; H O Kalkman; W Stühmer; H Lübbert
Journal:  EMBO J       Date:  1992-09       Impact factor: 11.598
  3 in total

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