PURPOSE: We assessed the associations between multimorbidity and health-related quality of life (HRQL), and healthcare utilization, based on 16 common self-reported chronic conditions. METHODS: A cross-sectional questionnaire survey including the EQ-5D was conducted in a sample of the general population of adults (≥18 years) living in Alberta, Canada. Multiple linear and logistic regressions were used to assess the association between multiple chronic conditions and HRQL, hospitalization and emergency department (ED) use. RESULTS: A total of 4,946 respondents reported their HRQL, noting problems mostly with pain or discomfort (48.0%). All chronic conditions were associated with a clinically important reduction in HRQL, the highest burden with anxiety or depression (-0.19, 95% CI -0.21, -0.16) and chronic pain (-0.19, 95% CI -0.21, -0.17). Multimorbidity was associated with a clinically important reduction in the EQ-5D index score (-0.12, 95% CI -0.14, -0.11) and twice the likelihood of being hospitalized (OR = 2.2, 95% CI 1.7, 2.9) or having an ED visit (OR = 1.8, 95% CI 1.4, 2.2). CONCLUSIONS: Pain or discomfort is a common problem in people living with chronic conditions, and the existence of multimorbidity in these individuals is associated with a reduction in the HRQL as well as frequent hospitalization and emergency department visits.
PURPOSE: We assessed the associations between multimorbidity and health-related quality of life (HRQL), and healthcare utilization, based on 16 common self-reported chronic conditions. METHODS: A cross-sectional questionnaire survey including the EQ-5D was conducted in a sample of the general population of adults (≥18 years) living in Alberta, Canada. Multiple linear and logistic regressions were used to assess the association between multiple chronic conditions and HRQL, hospitalization and emergency department (ED) use. RESULTS: A total of 4,946 respondents reported their HRQL, noting problems mostly with pain or discomfort (48.0%). All chronic conditions were associated with a clinically important reduction in HRQL, the highest burden with anxiety or depression (-0.19, 95% CI -0.21, -0.16) and chronic pain (-0.19, 95% CI -0.21, -0.17). Multimorbidity was associated with a clinically important reduction in the EQ-5D index score (-0.12, 95% CI -0.14, -0.11) and twice the likelihood of being hospitalized (OR = 2.2, 95% CI 1.7, 2.9) or having an ED visit (OR = 1.8, 95% CI 1.4, 2.2). CONCLUSIONS:Pain or discomfort is a common problem in people living with chronic conditions, and the existence of multimorbidity in these individuals is associated with a reduction in the HRQL as well as frequent hospitalization and emergency department visits.
Authors: Wolfgang Greiner; Tom Weijnen; Martin Nieuwenhuizen; Siem Oppe; Xavier Badia; Jan Busschbach; Martin Buxton; Paul Dolan; Paul Kind; Paul Krabbe; Arto Ohinmaa; David Parkin; Montserat Roset; Harri Sintonen; Aki Tsuchiya; Frank de Charro Journal: Eur J Health Econ Date: 2003-09
Authors: Martin Fortin; Gina Bravo; Catherine Hudon; Lise Lapointe; José Almirall; Marie-France Dubois; Alain Vanasse Journal: Qual Life Res Date: 2006-02 Impact factor: 4.147
Authors: Ruth M A van Nispen; Michiel R de Boer; Janneke G J Hoeijmakers; Peter J Ringens; Ger H M B van Rens Journal: Health Qual Life Outcomes Date: 2009-02-25 Impact factor: 3.186
Authors: Lee Cheng; Salimah Cumber; Carlos Dumas; Ronald Winter; Kim M Nguyen; Linda Z Nieman Journal: Health Qual Life Outcomes Date: 2003-10-31 Impact factor: 3.186
Authors: Luke Mondor; Colleen J Maxwell; Susan E Bronskill; Andrea Gruneir; Walter P Wodchis Journal: Qual Life Res Date: 2016-04-06 Impact factor: 4.147
Authors: Kathleen Lang; Ivy M Alexander; James Simon; Matthew Sussman; Iris Lin; Joseph Menzin; Mark Friedman; David Dutwin; Andrew G Bushmakin; Maia Thrift-Perry; Corrado Altomare; Ming-Ann Hsu Journal: J Womens Health (Larchmt) Date: 2015-05 Impact factor: 2.681
Authors: Susanne Schmitz; Tatjana T Makovski; Roisin Adams; Marjan van den Akker; Saverio Stranges; Maurice P Zeegers Journal: Pharmacoeconomics Date: 2020-01 Impact factor: 4.981
Authors: Christine S Ritchie; Fengmin Zhao; Kanan Patel; Judith Manola; Elizabeth A Kvale; Claire F Snyder; Michael J Fisch Journal: Cancer Date: 2017-06-13 Impact factor: 6.860
Authors: Akiko Kamimura; Nancy Christensen; Jamie A Prevedel; Jennifer Tabler; Brian J Hamilton; Jeanie Ashby; Justine J Reel Journal: J Community Health Date: 2014-06