Literature DB >> 22684369

MicroRNA control of epithelial-mesenchymal transition and metastasis.

Jinsong Zhang1, Li Ma.   

Abstract

The great majority of cancer deaths are due to metastasis, which remains a poorly understood pathological process. The formation of a metastasis reflects a succession of complex steps leading to the macroscopic outgrowth of disseminated tumor cells at the secondary site. In the past 5 years, certain microRNAs (miRNAs) have been shown to regulate either a single step or multiple steps of metastasis, doing so by downregulating the expression of their target genes. In this review, we discuss recent studies on the functions and molecular mechanisms of miRNAs in regulating epithelial-mesenchymal transition (EMT) and cancer metastasis.

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Year:  2012        PMID： 22684369      PMCID： PMC3686549          DOI： 10.1007/s10555-012-9368-6

Source DB:  PubMed          Journal:  Cancer Metastasis Rev        ISSN： 0167-7659            Impact factor:   9.264


  127 in total

1.  Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models.

Authors:  Huiping Liu; Manishkumar R Patel; Jennifer A Prescher; Antonia Patsialou; Dalong Qian; Jiahui Lin; Susanna Wen; Ya-Fang Chang; Michael H Bachmann; Yohei Shimono; Piero Dalerba; Maddalena Adorno; Neethan Lobo; Janet Bueno; Frederick M Dirbas; Sumanta Goswami; George Somlo; John Condeelis; Christopher H Contag; Sanjiv Sam Gambhir; Michael F Clarke
Journal:  Proc Natl Acad Sci U S A       Date:  2010-10-04       Impact factor: 11.205

2.  Concurrent suppression of integrin alpha5, radixin, and RhoA phenocopies the effects of miR-31 on metastasis.

Authors:  Scott Valastyan; Amelia Chang; Nathan Benaich; Ferenc Reinhardt; Robert A Weinberg
Journal:  Cancer Res       Date:  2010-06-08       Impact factor: 12.701

3.  miR-21 and miR-31 converge on TIAM1 to regulate migration and invasion of colon carcinoma cells.

Authors:  Charisa L Cottonham; Satoshi Kaneko; Lan Xu
Journal:  J Biol Chem       Date:  2010-09-07       Impact factor: 5.157

4.  MicroRNA-21 promotes the cell proliferation, invasion and migration abilities in ovarian epithelial carcinomas through inhibiting the expression of PTEN protein.

Authors:  Yanhui Lou; Xingsheng Yang; Fuling Wang; Zhumei Cui; Yu Huang
Journal:  Int J Mol Med       Date:  2010-12       Impact factor: 4.101

5.  The use of hsa-miR-21, hsa-miR-181b and hsa-miR-106a as prognostic indicators of astrocytoma.

Authors:  Feng Zhi; Xi Chen; Suinuan Wang; Xiwei Xia; Yimin Shi; Wei Guan; Naiyuan Shao; Hongtao Qu; Changchun Yang; Yi Zhang; Qiang Wang; Rong Wang; Ke Zen; Chen-Yu Zhang; Junfeng Zhang; Yilin Yang
Journal:  Eur J Cancer       Date:  2010-03-08       Impact factor: 9.162

6.  miR-661 expression in SNAI1-induced epithelial to mesenchymal transition contributes to breast cancer cell invasion by targeting Nectin-1 and StarD10 messengers.

Authors:  G Vetter; A Saumet; M Moes; L Vallar; A Le Béchec; C Laurini; M Sabbah; K Arar; C Theillet; C-H Lecellier; E Friederich
Journal:  Oncogene       Date:  2010-06-14       Impact factor: 9.867

7.  MicroRNA-10b induced by Epstein-Barr virus-encoded latent membrane protein-1 promotes the metastasis of human nasopharyngeal carcinoma cells.

Authors:  Gang Li; Zhengrong Wu; Ying Peng; Xiong Liu; Juan Lu; Lu Wang; Qiuhui Pan; Min-Liang He; Xiang-Ping Li
Journal:  Cancer Lett       Date:  2010-08-21       Impact factor: 8.679

8.  A MicroRNA targeting dicer for metastasis control.

Authors:  Graziano Martello; Antonio Rosato; Francesco Ferrari; Andrea Manfrin; Michelangelo Cordenonsi; Sirio Dupont; Elena Enzo; Vincenza Guzzardo; Maria Rondina; Thomas Spruce; Anna R Parenti; Maria Grazia Daidone; Silvio Bicciato; Stefano Piccolo
Journal:  Cell       Date:  2010-06-25       Impact factor: 41.582

9.  OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma.

Authors:  Pedro P Medina; Mona Nolde; Frank J Slack
Journal:  Nature       Date:  2010-08-08       Impact factor: 49.962

10.  A coding-independent function of gene and pseudogene mRNAs regulates tumour biology.

Authors:  Laura Poliseno; Leonardo Salmena; Jiangwen Zhang; Brett Carver; William J Haveman; Pier Paolo Pandolfi
Journal:  Nature       Date:  2010-06-24       Impact factor: 49.962
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  119 in total

1.  MicroRNA-218 inhibits gastrointestinal stromal tumor cell and invasion by targeting KIT.

Authors:  Rong Fan; Jie Zhong; Sichang Zheng; Zhengting Wang; Ying Xu; Shuyi Li; Jie Zhou; Fei Yuan
Journal:  Tumour Biol       Date:  2013-12-29

Review 2.  The emerging molecular machinery and therapeutic targets of metastasis.

Authors:  Yutong Sun; Li Ma
Journal:  Trends Pharmacol Sci       Date:  2015-05-01       Impact factor: 14.819

3.  A ZEB1-miR-375-YAP1 pathway regulates epithelial plasticity in prostate cancer.

Authors:  L A Selth; R Das; S L Townley; I Coutinho; A R Hanson; M M Centenera; N Stylianou; K Sweeney; C Soekmadji; L Jovanovic; C C Nelson; A Zoubeidi; L M Butler; G J Goodall; B G Hollier; P A Gregory; W D Tilley
Journal:  Oncogene       Date:  2016-06-06       Impact factor: 9.867

Review 4.  Regulation of epithelial-mesenchymal and mesenchymal-epithelial transitions by microRNAs.

Authors:  Samy Lamouille; Deepa Subramanyam; Robert Blelloch; Rik Derynck
Journal:  Curr Opin Cell Biol       Date:  2013-02-20       Impact factor: 8.382

5.  Inactivation of the Wnt/β-catenin signaling pathway underlies inhibitory role of microRNA-129-5p in epithelial-mesenchymal transition and angiogenesis of prostate cancer by targeting ZIC2.

Authors:  Zhenming Jiang; Yuxi Zhang; Xi Chen; Pingeng Wu; Dong Chen
Journal:  Cancer Cell Int       Date:  2019-10-21       Impact factor: 5.722

6.  A novel microRNA regulator of prostate cancer epithelial-mesenchymal transition.

Authors:  Nathan Bucay; Divya Bhagirath; Kirandeep Sekhon; Thao Yang; Shinichiro Fukuhara; Shahana Majid; Varahram Shahryari; ZLaura Tabatabai; Kirsten L Greene; Yutaka Hashimoto; Marisa Shiina; Soichiro Yamamura; Yuichiro Tanaka; Guoren Deng; Rajvir Dahiya; Sharanjot Saini
Journal:  Cell Death Differ       Date:  2017-05-12       Impact factor: 15.828

7.  Anti-invasive effect of Cyclamen pseudibericum extract on A549 non-small cell lung carcinoma cells via inhibition of ZEB1 mediated by miR-200c.

Authors:  Ege Riza Karagur; Cennet Ozay; Ramazan Mammadov; Hakan Akca
Journal:  J Nat Med       Date:  2018-03-19       Impact factor: 2.343

8.  Ablation of miR-10b Suppresses Oncogene-Induced Mammary Tumorigenesis and Metastasis and Reactivates Tumor-Suppressive Pathways.

Authors:  Jongchan Kim; Ashley N Siverly; Dahu Chen; Min Wang; Yuan Yuan; Yumeng Wang; Hyemin Lee; Jinsong Zhang; William J Muller; Han Liang; Boyi Gan; Xianbin Yang; Yutong Sun; M James You; Li Ma
Journal:  Cancer Res       Date:  2016-08-28       Impact factor: 12.701

Review 9.  Bioinformatic approaches to augment study of epithelial-to-mesenchymal transition in lung cancer.

Authors:  Tim N Beck; Adaeze J Chikwem; Nehal R Solanki; Erica A Golemis
Journal:  Physiol Genomics       Date:  2014-08-05       Impact factor: 3.107

10.  microRNA-218 suppresses the proliferation, invasion and promotes apoptosis of pancreatic cancer cells by targeting HMGB1.

Authors:  Zhe Liu; Yuanhong Xu; Jin Long; Kejian Guo; Chunlin Ge; Ruixia Du
Journal:  Chin J Cancer Res       Date:  2015-06       Impact factor: 5.087
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