Literature DB >> 22676254

Language development in school-age girls with fragile X syndrome.

A Sterling1, L Abbeduto.   

Abstract

BACKGROUND: Girls with fragile X syndrome (FXS) have a wide range of cognitive and language abilities. The range of language outcomes experienced by girls with FXS, however, has been relatively unexplored. The purpose of this exploratory study was to examine receptive and expressive language, with a focus on vocabulary and syntax, in a group of school-age girls with FXS.
METHOD: Twenty-one girls with FXS aged 7-15 years participated in the study. The girls completed a receptive vocabulary test, non-verbal IQ test and an expressive language sample.
RESULTS: The mean IQ for this group of girls was at the cut-off for intellectual disability. Vocabulary was an area of strength relative to non-verbal cognition. Age and non-verbal IQ were significant predictors of vocabulary performance.
CONCLUSIONS: The data suggest that a substantial portion of the sample would qualify for speech and language services. This study highlights the need for continued research in the area of language and cognitive development in girls with the full mutation of fragile X.
© 2012 The Authors. Journal of Intellectual Disability Research © 2012 Blackwell Publishing Ltd.

Entities:  

Mesh:

Year:  2012        PMID: 22676254      PMCID: PMC3627376          DOI: 10.1111/j.1365-2788.2012.01578.x

Source DB:  PubMed          Journal:  J Intellect Disabil Res        ISSN: 0964-2633


  28 in total

1.  Variability in FMRP and early development in males with fragile X syndrome.

Authors:  D B Bailey; D D Hatton; F Tassone; M Skinner; A K Taylor
Journal:  Am J Ment Retard       Date:  2001-01

2.  The fragile X prevalence paradox.

Authors:  Paul J Hagerman
Journal:  J Med Genet       Date:  2008-04-15       Impact factor: 6.318

3.  Profiles of receptive and expressive language abilities in boys with comorbid fragile X syndrome and autism.

Authors:  Andrea McDuffie; Sara Kover; Leonard Abbeduto; Pamela Lewis; Ted Brown
Journal:  Am J Intellect Dev Disabil       Date:  2012-01

Review 4.  Theoretical perspectives on language and communication problems in mental retardation and developmental disabilities.

Authors:  L Abbeduto; J Evans; T Dolan
Journal:  Ment Retard Dev Disabil Res Rev       Date:  2001

5.  Language use in females with fragile X or Turner syndrome during brief initial social interactions.

Authors:  Michèle M M Mazzocco; Laurie Thompson; Vicki Sudhalter; Richard C Belser; Katarzyna Lesniak-Karpiak; Judith L Ross
Journal:  J Dev Behav Pediatr       Date:  2006-08       Impact factor: 2.225

Review 6.  Language development and fragile X syndrome: profiles, syndrome-specificity, and within-syndrome differences.

Authors:  Leonard Abbeduto; Nancy Brady; Sara T Kover
Journal:  Ment Retard Dev Disabil Res Rev       Date:  2007

7.  Discourse processing in women with fragile x syndrome: evidence for a deficit establishing coherence.

Authors:  J A Simon; J M Keenan; B F Pennington; A K Taylor; R J Hagerman
Journal:  Cogn Neuropsychol       Date:  2001-02-01       Impact factor: 2.468

Review 8.  The fragile X mental retardation protein, FMRP, recognizes G-quartets.

Authors:  Jennifer C Darnell; Stephen T Warren; Robert B Darnell
Journal:  Ment Retard Dev Disabil Res Rev       Date:  2004

Review 9.  Identifying neurocognitive phenotypes in autism.

Authors:  Helen Tager-Flusberg; Robert M Joseph
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2003-02-28       Impact factor: 6.237

10.  Receptive vocabulary, expressive vocabulary, and speech production of boys with fragile X syndrome in comparison to boys with down syndrome.

Authors:  Joanne Roberts; Johanna Price; Elizabeth Barnes; Lauren Nelson; Margaret Burchinal; Elizabeth A Hennon; Lauren Moskowitz; Anne Edwards; Cheryl Malkin; Kathleen Anderson; Jan Misenheimer; Stephen R Hooper
Journal:  Am J Ment Retard       Date:  2007-05
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  16 in total

1.  A Description of the Educational Setting Among Individuals With Fragile X Syndrome.

Authors:  Rebecca Nash; Catharine Riley; Pangaja Paramsothy; Kendra Gilbertson; Melissa Raspa; Anne Wheeler; Eric J Dziuban; Georgina Peacock
Journal:  Am J Intellect Dev Disabil       Date:  2019-01

2.  Growth of Expressive Syntax in Children With Fragile X Syndrome.

Authors:  Rouzana Komesidou; Nancy C Brady; Kandace Fleming; Amy Esplund; Steven F Warren
Journal:  J Speech Lang Hear Res       Date:  2017-02-01       Impact factor: 2.297

Review 3.  Public Health Literature Review of Fragile X Syndrome.

Authors:  Melissa Raspa; Anne C Wheeler; Catharine Riley
Journal:  Pediatrics       Date:  2017-06       Impact factor: 7.124

4.  Maternal Responsiveness to Gestures in Children With Down Syndrome.

Authors:  Emily Lorang; Audra Sterling; Bianca Schroeder
Journal:  Am J Speech Lang Pathol       Date:  2018-08-06       Impact factor: 2.408

5.  Noncomprehension Signaling in Males and Females With Fragile X Syndrome.

Authors:  Angela John Thurman; Sara T Kover; W Ted Brown; Danielle J Harvey; Leonard Abbeduto
Journal:  J Speech Lang Hear Res       Date:  2017-06-10       Impact factor: 2.297

6.  Signaling of noncomprehension in communication breakdowns in fragile X syndrome, Down syndrome, and autism spectrum disorder.

Authors:  Gary E Martin; Jamie Barstein; Jane Hornickel; Sara Matherly; Genna Durante; Molly Losh
Journal:  J Commun Disord       Date:  2017-01-26       Impact factor: 2.288

7.  Language comprehension profiles of young adolescents with fragile X syndrome.

Authors:  Ashley Oakes; Sara T Kover; Leonard Abbeduto
Journal:  Am J Speech Lang Pathol       Date:  2013-06-28       Impact factor: 2.408

8.  An investigation into maternal use of telegraphic input to children with Down syndrome.

Authors:  Emily Lorang; Courtney E Venker; Audra Sterling
Journal:  J Child Lang       Date:  2019-10-07

9.  Syntactic Ability of Girls With Fragile X Syndrome: Phonological Memory and Discourse Demands on Complex Sentence Use.

Authors:  Sara T Kover; Leonard Abbeduto
Journal:  Am J Intellect Dev Disabil       Date:  2019-11

10.  The impact of autism spectrum disorder symptoms on gesture use in fragile X syndrome and Down syndrome.

Authors:  Emily Lorang; Audra Sterling
Journal:  Autism Dev Lang Impair       Date:  2017-12-25
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