Literature DB >> 22673844

What the emergency radiologist needs to know about treatment-related complications from conventional chemotherapy and newer molecular targeted agents.

Sona A Chikarmane1, Bharti Khurana, Katherine M Krajewski, Atul B Shinagare, Stephanie Howard, Aaron Sodickson, Jyothi Jagannathan, Nikhil Ramaiya.   

Abstract

Emergency departments (ED) are increasingly utilized by oncology patients for disease- and treatment-related issues. With the increased use of new molecular targeted therapy (MTT) and conventional chemotherapeutic regimens, oncology patients present with a range of adverse treatment effects, some of which reveal characteristic injury patterns and imaging appearances. Knowledge of these imaging findings is critically important for early detection and prompt management in oncology patients. In this article, we present a brief review of conventional chemotherapeutic and new MTT regimens as well as address adverse reactions that bring oncology patients to the ED.

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Year:  2012        PMID: 22673844     DOI: 10.1007/s10140-012-1052-1

Source DB:  PubMed          Journal:  Emerg Radiol        ISSN: 1070-3004


  37 in total

Review 1.  Subtrochanteric femoral insufficiency fractures related to the use of long-term bisphosphonates: a pictorial review.

Authors:  Nanda Venkatanarasimha; Gemma Miles; Priya Suresh
Journal:  Emerg Radiol       Date:  2010-07-20

2.  Pneumatosis intestinalis: a variant of bevacizumab related perforation possibly associated with chemotherapy related GI toxicity.

Authors:  Timothy R Asmis; Ki Y Chung; Jerrold B Teitcher; David P Kelsen; Manish A Shah
Journal:  Invest New Drugs       Date:  2007-10-26       Impact factor: 3.850

Review 3.  Practical management of tyrosine kinase inhibitor-associated side effects in GIST.

Authors:  Heikki Joensuu; Jonathan C Trent; Peter Reichardt
Journal:  Cancer Treat Rev       Date:  2010-05-31       Impact factor: 12.111

Review 4.  Drug-associated pancreatitis: facts and fiction.

Authors:  M Rünzi; P Layer
Journal:  Pancreas       Date:  1996-07       Impact factor: 3.327

5.  Nonoperative versus prophylactic treatment of bisphosphonate-associated femoral stress fractures.

Authors:  Michael B Banffy; Mark S Vrahas; John E Ready; John A Abraham
Journal:  Clin Orthop Relat Res       Date:  2011-02-25       Impact factor: 4.176

6.  Case report of pneumatosis intestinalis secondary to sunitinib treatment for refractory gastrointestinal stromal tumor.

Authors:  Anthony Jarkowski; Ryan Hare; Valerie Francescutti; Neal Wilkinson; Nikhil Khushalani
Journal:  Anticancer Res       Date:  2011-10       Impact factor: 2.480

7.  Venous thromboembolic events with chemotherapy plus bevacizumab: a pooled analysis of patients in randomized phase II and III studies.

Authors:  Herbert I Hurwitz; Leonard B Saltz; Eric Van Cutsem; James Cassidy; Jonas Wiedemann; Florin Sirzén; Gary H Lyman; Ulrich-Peter Rohr
Journal:  J Clin Oncol       Date:  2011-03-21       Impact factor: 44.544

8.  Transient leukoencephalopathy after intrathecal methotrexate mimicking stroke.

Authors:  Amit Agarwal; Kanupriya Vijay; Krishnamoorthy Thamburaj; Tao Ouyang
Journal:  Emerg Radiol       Date:  2011-01-18

9.  Phase II study to investigate the efficacy, safety, and pharmacokinetics of sorafenib in Japanese patients with advanced renal cell carcinoma.

Authors:  Hideyuki Akaza; Taiji Tsukamoto; Masaru Murai; Keiko Nakajima; Seiji Naito
Journal:  Jpn J Clin Oncol       Date:  2007-10-19       Impact factor: 3.019

Review 10.  Gastrointestinal stromal tumor: role of CT in diagnosis and in response evaluation and surveillance after treatment with imatinib.

Authors:  Xie Hong; Haesun Choi; Evelyne M Loyer; Robert S Benjamin; Jonathan C Trent; Chusilp Charnsangavej
Journal:  Radiographics       Date:  2006 Mar-Apr       Impact factor: 5.333

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  5 in total

1.  Atypical reversible posterior leukoencephalopathy syndrome (RPLS) induced by cediranib in a patient with metastatic rectal cancer.

Authors:  Christina A K Kim; Julie Price-Hiller; Quincy S Chu; Keith Tankel; Ron Hennig; Michael B Sawyer; Jennifer L Spratlin
Journal:  Invest New Drugs       Date:  2014-05-23       Impact factor: 3.850

Review 2.  Update on the management of gastroenteropancreatic neuroendocrine tumors with emphasis on the role of imaging.

Authors:  Kyung Won Kim; Katherine M Krajewski; Mizuki Nishino; Jyothi P Jagannathan; Atul B Shinagare; Sree Harsha Tirumani; Nikhil H Ramaiya
Journal:  AJR Am J Roentgenol       Date:  2013-10       Impact factor: 3.959

Review 3.  Update on the role of imaging in management of metastatic colorectal cancer.

Authors:  Sree Harsha Tirumani; Kyung Won Kim; Mizuki Nishino; Stephanie A Howard; Katherine M Krajewski; Jyothi P Jagannathan; James M Cleary; Nikhil H Ramaiya; Atul B Shinagare
Journal:  Radiographics       Date:  2014 Nov-Dec       Impact factor: 5.333

Review 4.  Clinical problem solving: utility of sonography in oncologic patients.

Authors:  Christine Cooley; Mizuki Nishino; Jyothi Jagannathan; Nikhil Ramaiya; Donald Di Salvo; Katherine M Krajewski
Journal:  J Ultrasound Med       Date:  2014-01       Impact factor: 2.153

Review 5.  Molecular targeted therapies in non-GIST soft tissue sarcomas: what the radiologist needs to know.

Authors:  Sree Harsha Tirumani; Jyothi P Jagannathan; Kevin O'Regan; Kyung Won Kim; Atul B Shinagare; Katherine M Krajewski; Nikhil H Ramaiya
Journal:  Cancer Imaging       Date:  2013-05-02       Impact factor: 3.909

  5 in total

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