Literature DB >> 22667683

A novel device to apply controlled flexion and extension to the rat knee following anterior cruciate ligament reconstruction.

Mark E Stasiak1, Dan Wiznia, Saif Alzoobaee, Michael C Ciccotti, Carl W Imhauser, Clifford Voigt, Peter A Torzilli, Xiang-Hua Deng, Scott A Rodeo.   

Abstract

We designed and validated a novel device for applying flexion-extension cycles to a rat knee in an in vivo model of anterior cruciate ligament reconstruction (ACL-R). Our device is intended to simulate rehabilitation motion and exercise post ACL-R to optimize physical rehabilitation treatments for the improved healing of tendon graft ligament reconstructions. The device was validated for repeatability of the knee kinematic motion by measuring the force versus angular rotation response from repeated trials using cadaver rats. The average maximum force required for rotating an ACL reconstructed rat knee through 100 degrees of flexion-extension was 0.4 N with 95% variability for all trials within ±0.1 N.

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Year:  2012        PMID： 22667683      PMCID： PMC3650617          DOI： 10.1115/1.4006341

Source DB:  PubMed          Journal:  J Biomech Eng        ISSN： 0148-0731            Impact factor:   2.097


  16 in total

1.  Effect of early and delayed mechanical loading on tendon-to-bone healing after anterior cruciate ligament reconstruction.

Authors:  Asheesh Bedi; David Kovacevic; Alice J S Fox; Carl W Imhauser; Mark Stasiak; Jonathan Packer; Robert H Brophy; Xiang-Hua Deng; Scott A Rodeo
Journal:  J Bone Joint Surg Am       Date:  2010-10-20       Impact factor: 5.284

2.  Anterior cruciate ligament revision reconstruction: two-year results from the MOON cohort.

Authors:  Rick W Wright; Warren R Dunn; Annunziato Amendola; Jack T Andrish; David C Flanigan; Morgan Jones; Christopher C Kaeding; Robert G Marx; Matthew J Matava; Eric C McCarty; Richard D Parker; Armando Vidal; Michelle Wolcott; Brian R Wolf; Kurt P Spindler
Journal:  J Knee Surg       Date:  2007-10       Impact factor: 2.757

Review 3.  "Biological failure" of the anterior cruciate ligament graft.

Authors:  J Ménétrey; V B Duthon; T Laumonier; D Fritschy
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2008-01-09       Impact factor: 4.342

Review 4.  Ipsilateral graft and contralateral ACL rupture at five years or more following ACL reconstruction: a systematic review.

Authors:  Rick W Wright; Robert A Magnussen; Warren R Dunn; Kurt P Spindler
Journal:  J Bone Joint Surg Am       Date:  2011-06-15       Impact factor: 5.284

5.  Effect of short-duration low-magnitude cyclic loading versus immobilization on tendon-bone healing after ACL reconstruction in a rat model.

Authors:  Robert H Brophy; David Kovacevic; Carl W Imhauser; Mark Stasiak; Asheesh Bedi; Alice J S Fox; Xiang-Hua Deng; Scott A Rodeo
Journal:  J Bone Joint Surg Am       Date:  2011-02-16       Impact factor: 5.284

6.  A Novel In Vivo Joint Loading System to Investigate the Effect of Daily Mechanical Load on a Healing Anterior Cruciate Ligament Reconstruction.

Authors:  Mark Stasiak; Carl Imhauser; Jonathan Packer; Asheesh Bedi; Robert Brophy; David Kovacevic; Kent Jackson; Xiang-Hua Deng; Scott Rodeo; Peter Torzilli
Journal:  J Med Device       Date:  2010       Impact factor: 0.582

7.  Tendon healing in a bone tunnel differs at the tunnel entrance versus the tunnel exit: an effect of graft-tunnel motion?

Authors:  Scott A Rodeo; Sumito Kawamura; Hyon-Jeong Kim; Christian Dynybil; Liang Ying
Journal:  Am J Sports Med       Date:  2006-07-21       Impact factor: 6.202

8.  Development and validation of a motion and loading system for a rat knee joint in vivo.

Authors:  Xiang Ian Gu; Daniel J Leong; Francisco Guzman; Rashal Mahamud; Yong Hui Li; Robert J Majeska; Mitchell B Schaffler; Hui Bin Sun; Luis Cardoso
Journal:  Ann Biomed Eng       Date:  2009-12-16       Impact factor: 3.934

Review 9.  A systematic review of anterior cruciate ligament reconstruction rehabilitation: part I: continuous passive motion, early weight bearing, postoperative bracing, and home-based rehabilitation.

Authors:  Rick W Wright; Emily Preston; Braden C Fleming; Annunziato Amendola; Jack T Andrish; John A Bergfeld; Warren R Dunn; Chris Kaeding; John E Kuhn; Robert G Marx; Eric C McCarty; Richard C Parker; Kurt P Spindler; Michelle Wolcott; Brian R Wolf; Glenn N Williams
Journal:  J Knee Surg       Date:  2008-07       Impact factor: 2.757

10.  Tendon-healing in a bone tunnel. A biomechanical and histological study in the dog.

Authors:  S A Rodeo; S P Arnoczky; P A Torzilli; C Hidaka; R F Warren
Journal:  J Bone Joint Surg Am       Date:  1993-12       Impact factor: 5.284
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  1 in total

1.  Athymic rat model for evaluation of engineered anterior cruciate ligament grafts.

Authors:  Natalie L Leong; Nima Kabir; Armin Arshi; Azadeh Nazemi; Ben M Wu; David R McAllister; Frank A Petrigliano
Journal:  J Vis Exp       Date:  2015-03-26       Impact factor: 1.355
  1 in total

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