Literature DB >> 22665553

Triple negative mixed metaplastic breast carcinoma with squamous and spindle cells in an 84-year-old woman: a rare entity with unclear management strategy and poor prognosis.

Srujitha Murukutla1, Vijaya Raj Bhatt, Abhirami Vivekanandarajah, Cynara Coomer, Shilpi Gupta.   

Abstract

Metaplastic carcinoma of the breast, a rare neoplasm, usually presents at an advanced stage, metastasises to distant sites more frequently, has higher Ki-67 expression and is more often triple negative compared with other invasive breast cancers. Here, the authors discuss a case of an 84-year-old woman with triple negative mixed metaplastic breast carcinoma treated with radical modified mastectomy, axillary lymph node dissection and radiation therapy. Because of the rarity of the disease, the pathogenesis and the management remain controversial, thus contributing to overall poor prognosis.

Entities:  

Mesh:

Year:  2012        PMID: 22665553      PMCID: PMC3291009          DOI: 10.1136/bcr.10.2011.5044

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  24 in total

1.  Twelve cases of metaplastic carcinoma of the breast: experience of the university hospital of Fez Morocco.

Authors:  Kaoutar Znati; Sanaa Chahbouni; Nawal Hammas; Sanaa Bennis; Fouad Abbas; Taoufiq Harmouch; Laila Chbani; Hind Elfatemi; Afaf Amarti
Journal:  Arch Gynecol Obstet       Date:  2010-05-08       Impact factor: 2.344

2.  Metaplastic breast carcinomas: are they of myoepithelial differentiation?: immunohistochemical profile of the sarcomatoid subtype using novel myoepithelial markers.

Authors:  Sebastian Leibl; Margit Gogg-Kammerer; Andrea Sommersacher; Helmut Denk; Farid Moinfar
Journal:  Am J Surg Pathol       Date:  2005-03       Impact factor: 6.394

3.  Squamous cell carcinoma of the breast.

Authors:  Bryan T Hennessy; Savitri Krishnamurthy; Sharon Giordano; Thomas A Buchholz; Shu W Kau; Zhigang Duan; Vicente Valero; Gabriel N Hortobagyi
Journal:  J Clin Oncol       Date:  2005-11-01       Impact factor: 44.544

4.  Characteristics and treatment of metaplastic breast cancer: analysis of 892 cases from the National Cancer Data Base.

Authors:  Christopher M Pezzi; Lina Patel-Parekh; Karin Cole; Jan Franko; V Suzanne Klimberg; Kirby Bland
Journal:  Ann Surg Oncol       Date:  2006-10-26       Impact factor: 5.344

5.  [Metaplastic carcinoma of the breast: magnetic resonance and radiophatologic correlation].

Authors:  A Massuet; S Fernández; J Rimola; F J Andreu; L Tortajada; M Sentís
Journal:  Radiologia       Date:  2006 May-Jun

6.  Metaplastic carcinomas of the breast.

Authors:  T C Chao; C S Wang; S C Chen; M F Chen
Journal:  J Surg Oncol       Date:  1999-08       Impact factor: 3.454

7.  Metaplastic breast carcinomas are negative for Her-2 but frequently express EGFR (Her-1): potential relevance to adjuvant treatment with EGFR tyrosine kinase inhibitors?

Authors:  S Leibl; F Moinfar
Journal:  J Clin Pathol       Date:  2005-07       Impact factor: 3.411

Review 8.  Metaplastic carcinoma of the breast, an unusual disease with worse prognosis: the experience of the European Institute of Oncology and review of the literature.

Authors:  Alberto Luini; Marisel Aguilar; Giovanna Gatti; Roberta Fasani; Edoardo Botteri; Jack Antonio Diaz Brito; Patrick Maisonneuve; Anna Rita Vento; Giuseppe Viale
Journal:  Breast Cancer Res Treat       Date:  2006-09-29       Impact factor: 4.872

9.  Metaplastic carcinoma of the breast clinical presentation, treatment results and prognostic factors.

Authors:  Adher D Al Sayed; Amr N El Weshi; Asma M Tulbah; Mohamed M Rahal; Adnan A Ezzat
Journal:  Acta Oncol       Date:  2006       Impact factor: 4.089

10.  Laminin 5 expression in metaplastic breast carcinomas.

Authors:  Philip M Carpenter; Jessica Wang-Rodriguez; Owen T M Chan; Sharon P Wilczynski
Journal:  Am J Surg Pathol       Date:  2008-03       Impact factor: 6.394

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