Literature DB >> 22654326

Clinico-Microbiological Aspects of Necrotising Fasciitis in Type II Diabetes Mellitus.

Asayas Bosco Chandra Kumar1, S G Subramanyam, Arun B Kilpadi.   

Abstract

Necrotising fasciitis is insidiously advancing soft tissue infection, characterized by widespread fascial necrosis. One of the most common conditions encountered in the clinical practice and which required clinical suspicion in patients who have less resistance to these infections. Especially in diabetic patients who are more prone for such infection due to low immunity and other reasons like early detection of these infections helps these patients to have a better recovery by aggressive surgical management and other measures required for the same. Literature has enough evidence on how serious this entity. Hence this study is designed in that aspect to help in early diagnosis and appropriate treatment. This study will help to determine the clinical presentation, the polymicrobial involved. The organisms most closely linked to necrotizing fasciitis are group A beta-hemolytic streptococci, although the disease may also be caused by other bacteria and their sensitivity patterns will help us to install appropriate antibiotics with the surgical management. And to compare our mortality rate with the other studies. A prospective descriptive study including all type II diabetic patients with necrotizing fasciitis over 3 years. Patients were evaluated in detail with respect to patient's history, examination, culture sensitivity and chart reviews and followed up using standard evaluation tools to measure the various outcomes. In 62 patients, the commonest clinical presentation was necrotic patch of skin and cellulites. The organisms cultured being beta hemolytic streptococci and E.Coli. The culture sensitivity pattern is to broad-spectrum antibiotics. The average stay in the hospital was about 13.74 days for the study group and the time delay in presentation is 6 days. Wagner's score is a useful tool for aiding the diagnosis. Patients without foot care had extensive lesions. And a mortality rate of 1.6 % in these patients. In an acutely swollen limb in a diabetic patient a high degree of suspicion of necrotizing fasciitis is required. A detailed foot care is warranted in these patients. An early extensive debridement is mandatory and key for a favorable outcome. And to start on broad- spectrum antibiotics is advisable. Wagner's scoring is helpful to predict the chances of a second surgery. With the above entities in mind the mortality rate of necrotizing fasciitis in type ii diabetes mellitus can be contained.

Entities:  

Keywords:  NF - Necrotizing fasciitis; Polybacterial infections; Type II diabetes mellitus

Year:  2011        PMID: 22654326      PMCID: PMC3087059          DOI: 10.1007/s12262-010-0116-2

Source DB:  PubMed          Journal:  Indian J Surg        ISSN: 0973-9793            Impact factor:   0.656


  14 in total

1.  The microbiology of necrotizing soft tissue infections.

Authors:  D Elliott; J A Kufera; R A Myers
Journal:  Am J Surg       Date:  2000-05       Impact factor: 2.565

2.  Necrotizing fasciitis.

Authors:  W J Rea; W J Wyrick
Journal:  Ann Surg       Date:  1970-12       Impact factor: 12.969

3.  Necrotizing fasciitis of the head and neck: an analysis of 47 cases.

Authors:  C Lin; F L Yeh; J T Lin; H Ma; C H Hwang; B H Shen; R H Fang
Journal:  Plast Reconstr Surg       Date:  2001-06       Impact factor: 4.730

4.  A simple model to help distinguish necrotizing fasciitis from nonnecrotizing soft tissue infection.

Authors:  D B Wall; S R Klein; S Black; C de Virgilio
Journal:  J Am Coll Surg       Date:  2000-09       Impact factor: 6.113

5.  Zygomycotic necrotizing fasciitis in immunocompetent patients: a series of 18 cases.

Authors:  Deepali Jain; Yashwant Kumar; Rakesh K Vasishta; Logasundaram Rajesh; Sanjib K Pattari; Arunaloke Chakrabarti
Journal:  Mod Pathol       Date:  2006-06-02       Impact factor: 7.842

6.  Necrotizing fasciitis: report of 39 pediatric cases.

Authors:  Antonio Fustes-Morales; Pedro Gutierrez-Castrellon; Carola Duran-Mckinster; Luz Orozco-Covarrubias; Lourdes Tamayo-Sanchez; Ramon Ruiz-Maldonado
Journal:  Arch Dermatol       Date:  2002-07

7.  Necrotizing fasciitis: clinical presentation, microbiology, and determinants of mortality.

Authors:  Chin-Ho Wong; Haw-Chong Chang; Shanker Pasupathy; Lay-Wai Khin; Jee-Lim Tan; Cheng-Ooi Low
Journal:  J Bone Joint Surg Am       Date:  2003-08       Impact factor: 5.284

8.  Fulminant group A streptococcal necrotizing fasciitis: clinical and pathologic findings in 7 patients.

Authors:  Patrick R Dahl; Charles Perniciaro; Kristina A Holmkvist; Mary I O'Connor; Lawrence E Gibson
Journal:  J Am Acad Dermatol       Date:  2002-10       Impact factor: 11.527

9.  Progressive necrotizing surgical infections--a unified approach.

Authors:  R E Kaiser; F B Cerra
Journal:  J Trauma       Date:  1981-05

Review 10.  Necrotizing fasciitis: a clinical, microbiologic, and histopathologic study of 14 patients.

Authors:  I J Umbert; R K Winkelmann; G F Oliver; M S Peters
Journal:  J Am Acad Dermatol       Date:  1989-05       Impact factor: 11.527

View more
  1 in total

1.  Distribution and drug sensitivity of pathogenic bacteria in diabetic foot ulcer patients with necrotizing fasciitis at a diabetic foot center in China.

Authors:  Xuemei Li; Zhipeng Du; Ziwei Tang; Qin Wen; Qingfeng Cheng; Yunhua Cui
Journal:  BMC Infect Dis       Date:  2022-04-22       Impact factor: 3.667

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.