Literature DB >> 22647939

Molecular mechanisms underlying adhesion and migration of hematopoietic stem cells.

Aysegul Ocal Sahin1, Miranda Buitenhuis.   

Abstract

Hematopoietic stem cell transplantation is the most powerful treatment modality for a large number of hematopoietic malignancies, including leukemia. Successful hematopoietic recovery after transplantation depends on homing of hematopoietic stem cells to the bone marrow and subsequent lodging of those cells in specific niches in the bone marrow. Migration of hematopoietic stem cells to the bone marrow is a highly regulated process that requires correct regulation of the expression and activity of various molecules including chemoattractants, selectins and integrins. This review will discuss recent studies that have extended our understanding of the molecular mechanisms underlying adhesion, migration and bone marrow homing of hematopoietic stem cells.

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Year:  2012        PMID： 22647939      PMCID： PMC3364136          DOI： 10.4161/cam.18975

Source DB:  PubMed          Journal:  Cell Adh Migr        ISSN： 1933-6918            Impact factor:   3.405


  106 in total

1.  Rho GTPases control migration and polarization of adhesion molecules and cytoskeletal ERM components in T lymphocytes.

Authors:  M A del Pozo; M Vicente-Manzanares; R Tejedor; J M Serrador; F Sánchez-Madrid
Journal:  Eur J Immunol       Date:  1999-11       Impact factor: 5.532

2.  Stromal derived factor-1-induced chemokinesis of cord blood CD34(+) cells (long-term culture-initiating cells) through endothelial cells is mediated by E-selectin.

Authors:  A J Naiyer; D Y Jo; J Ahn; R Mohle; M Peichev; G Lam; R L Silverstein; M A Moore; S Rafii
Journal:  Blood       Date:  1999-12-15       Impact factor: 22.113

3.  Selective transendothelial migration of hematopoietic progenitor cells: a role in homing of progenitor cells.

Authors:  K Imai; M Kobayashi; J Wang; Y Ohiro; J Hamada; Y Cho; M Imamura; M Musashi; T Kondo; M Hosokawa; M Asaka
Journal:  Blood       Date:  1999-01-01       Impact factor: 22.113

4.  The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways.

Authors:  R K Ganju; S A Brubaker; J Meyer; P Dutt; Y Yang; S Qin; W Newman; J E Groopman
Journal:  J Biol Chem       Date:  1998-09-04       Impact factor: 5.157

5.  Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4.

Authors:  A Peled; I Petit; O Kollet; M Magid; T Ponomaryov; T Byk; A Nagler; H Ben-Hur; A Many; L Shultz; O Lider; R Alon; D Zipori; T Lapidot
Journal:  Science       Date:  1999-02-05       Impact factor: 47.728

6.  The chemokine SDF-1 stimulates integrin-mediated arrest of CD34(+) cells on vascular endothelium under shear flow.

Authors:  A Peled; V Grabovsky; L Habler; J Sandbank; F Arenzana-Seisdedos; I Petit; H Ben-Hur; T Lapidot; R Alon
Journal:  J Clin Invest       Date:  1999-11       Impact factor: 14.808

7.  CXCR4-transgene expression significantly improves marrow engraftment of cultured hematopoietic stem cells.

Authors:  Sebastian Brenner; Narda Whiting-Theobald; Toshinao Kawai; Gilda F Linton; Andrew G Rudikoff; Uimook Choi; Martin F Ryser; Philip M Murphy; Joan M G Sechler; Harry L Malech
Journal:  Stem Cells       Date:  2004       Impact factor: 6.277

8.  Endothelial selectins and vascular cell adhesion molecule-1 promote hematopoietic progenitor homing to bone marrow.

Authors:  P S Frenette; S Subbarao; I B Mazo; U H von Andrian; D D Wagner
Journal:  Proc Natl Acad Sci U S A       Date:  1998-11-24       Impact factor: 11.205

9.  Surface fucosylation of human cord blood cells augments binding to P-selectin and E-selectin and enhances engraftment in bone marrow.

Authors:  Lijun Xia; J Michael McDaniel; Tadayuki Yago; Andrea Doeden; Rodger P McEver
Journal:  Blood       Date:  2004-07-27       Impact factor: 22.113

10.  The sialomucin CD164 (MGC-24v) is an adhesive glycoprotein expressed by human hematopoietic progenitors and bone marrow stromal cells that serves as a potent negative regulator of hematopoiesis.

Authors:  A C Zannettino; H J Bühring; S Niutta; S M Watt; M A Benton; P J Simmons
Journal:  Blood       Date:  1998-10-15       Impact factor: 22.113
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  54 in total

1.  Cell Adhesion Molecule CD166 Drives Malignant Progression and Osteolytic Disease in Multiple Myeloma.

Authors:  Linlin Xu; Khalid S Mohammad; Hao Wu; Colin Crean; Bradley Poteat; Yinghua Cheng; Angelo A Cardoso; Christophe Machal; Helmut Hanenberg; Rafat Abonour; Melissa A Kacena; John Chirgwin; Attaya Suvannasankha; Edward F Srour
Journal:  Cancer Res       Date:  2016-09-07       Impact factor: 12.701

2.  Cannabinoid Receptor-2 Regulates Embryonic Hematopoietic Stem Cell Development via Prostaglandin E2 and P-Selectin Activity.

Authors:  Virginie Esain; Wanda Kwan; Kelli J Carroll; Mauricio Cortes; Sarah Y Liu; Gregory M Frechette; Lea M V Sheward; Sahar Nissim; Wolfram Goessling; Trista E North
Journal:  Stem Cells       Date:  2015-05-26       Impact factor: 6.277

3.  Migration against the direction of flow is LFA-1-dependent in human hematopoietic stem and progenitor cells.

Authors:  Alexander Buffone; Nicholas R Anderson; Daniel A Hammer
Journal:  J Cell Sci       Date:  2018-01-10       Impact factor: 5.285

4.  Fusing VE-cadherin to α-catenin impairs fetal liver hematopoiesis and lymph but not blood vessel formation.

Authors:  Nina Dartsch; Dörte Schulte; René Hägerling; Friedemann Kiefer; Dietmar Vestweber
Journal:  Mol Cell Biol       Date:  2014-02-24       Impact factor: 4.272

Review 5.  Current Understanding of the Pathways Involved in Adult Stem and Progenitor Cell Migration for Tissue Homeostasis and Repair.

Authors:  Polina Goichberg
Journal:  Stem Cell Rev Rep       Date:  2016-08       Impact factor: 5.739

Review 6.  Role of Liposomes-Based Stem Cell for Multimodal Cancer Therapy.

Authors:  Pankaj Mandpe; Bala Prabhakar; Pravin Shende
Journal:  Stem Cell Rev Rep       Date:  2020-02       Impact factor: 5.739

7.  α5β1 Integrin Promotes Anchoring and Integration of Transplanted Stem Cells to the Trabecular Meshwork in the Eye for Regeneration.

Authors:  Siqi Xiong; Yi Xu; Yiwen Wang; Ajay Kumar; Donna M Peters; Yiqin Du
Journal:  Stem Cells Dev       Date:  2020-01-20       Impact factor: 3.272

8.  A robust approach for the generation of functional hematopoietic progenitor cell lines to model leukemic transformation.

Authors:  Eszter Doma; Isabella Maria Mayer; Tania Brandstoetter; Barbara Maurer; Reinhard Grausenburger; Ingeborg Menzl; Markus Zojer; Andrea Hoelbl-Kovacic; Leif Carlsson; Gerwin Heller; Karoline Kollmann; Veronika Sexl
Journal:  Blood Adv       Date:  2021-01-12

9.  Conditioned Medium From Azurin-Expressing Human Mesenchymal Stromal Cells Demonstrates Antitumor Activity Against Breast and Lung Cancer Cell Lines.

Authors:  Marília Silva; Gabriel Amaro Monteiro; Arsenio M Fialho; Nuno Bernardes; Cláudia Lobato da Silva
Journal:  Front Cell Dev Biol       Date:  2020-07-09

10.  G protein-coupled receptors engage the mammalian Hippo pathway through F-actin: F-Actin, assembled in response to Galpha12/13 induced RhoA-GTP, promotes dephosphorylation and activation of the YAP oncogene.

Authors:  Laura Regué; Fan Mou; Joseph Avruch
Journal:  Bioessays       Date:  2013-03-01       Impact factor: 4.345
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