Literature DB >> 22647779

Rheumatoid arthritis. Evidence for a genetic component to disease severity in RA.

Eli A Stahl1, Soumya Raychaudhuri.   

Abstract

Rheumatoid arthritis (RA) is partly heritable; genetic and serological markers are known to confer risk of developing pathology. But given clinical heterogeneity in RA, can we predict who will develop severe disease? Substantial heritability of erosive progression rates has now been identified, but better prognostic biomarkers remain wanting.

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Year:  2012        PMID： 22647779      PMCID： PMC3668790          DOI： 10.1038/nrrheum.2012.74

Source DB:  PubMed          Journal:  Nat Rev Rheumatol        ISSN： 1759-4790            Impact factor:   20.543


  9 in total

1.  Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins.

Authors:  A J MacGregor; H Snieder; A S Rigby; M Koskenvuo; J Kaprio; K Aho; A J Silman
Journal:  Arthritis Rheum       Date:  2000-01

2.  Genetic studies on rheumatoid arthritis.

Authors:  J S LAWRENCE; J BALL
Journal:  Ann Rheum Dis       Date:  1958-06       Impact factor: 19.103

3.  Genetic predisposition of the severity of joint destruction in rheumatoid arthritis: a population-based study.

Authors:  Rachel Knevel; Gerður Gröndal; Tom W J Huizinga; A Willemien Visser; Helgi Jónsson; Arnór Víkingsson; Arni Jón Geirsson; Kristján Steinsson; Annette H M van der Helm-van Mil
Journal:  Ann Rheum Dis       Date:  2012-01-04       Impact factor: 19.103

4.  Variation in radiologic joint destruction in rheumatoid arthritis differs between monozygotic and dizygotic twins and pairs of unrelated patients.

Authors:  Annette H M van der Helm-van Mil; M Kern; Peter K Gregersen; Tom W J Huizinga
Journal:  Arthritis Rheum       Date:  2006-06

Review 5.  Genetic influences modulating the radiological severity of rheumatoid arthritis.

Authors:  I Marinou; J R Maxwell; A G Wilson
Journal:  Ann Rheum Dis       Date:  2010-02-02       Impact factor: 19.103

6.  Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid arthritis.

Authors:  Floris A van Gaalen; Jill van Aken; Tom W J Huizinga; Geziena M Th Schreuder; Ferdinand C Breedveld; Eric Zanelli; Walther J van Venrooij; Cornelis L Verweij; René E M Toes; René R P de Vries
Journal:  Arthritis Rheum       Date:  2004-07

7.  Prognostic laboratory markers of joint damage in rheumatoid arthritis.

Authors:  E Lindqvist; K Eberhardt; K Bendtzen; D Heinegård; T Saxne
Journal:  Ann Rheum Dis       Date:  2004-09-30       Impact factor: 19.103

8.  Assumption-free estimation of heritability from genome-wide identity-by-descent sharing between full siblings.

Authors:  Peter M Visscher; Sarah E Medland; Manuel A R Ferreira; Katherine I Morley; Gu Zhu; Belinda K Cornes; Grant W Montgomery; Nicholas G Martin
Journal:  PLoS Genet       Date:  2006-03-24       Impact factor: 5.917

Review 9.  The need for prognosticators in rheumatoid arthritis. Biological and clinical markers: where are we now?

Authors:  Josef S Smolen; Daniel Aletaha; Johannes Grisar; Kurt Redlich; Günter Steiner; Oswald Wagner
Journal:  Arthritis Res Ther       Date:  2008-05-29       Impact factor: 5.156
  9 in total
  1 in total

Review 1.  Poor prognostic factors guiding treatment decisions in rheumatoid arthritis patients: a review of data from randomized clinical trials and cohort studies.

Authors:  Katinka Albrecht; Angela Zink
Journal:  Arthritis Res Ther       Date:  2017-03-23       Impact factor: 5.156
  1 in total

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