Literature DB >> 22647379

VEGF-A engages at least three tyrosine kinases to activate PI3K/Akt.

Guo-Xiang Ruan, Andrius Kazlauskas.   

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Year:  2012        PMID： 22647379      PMCID： PMC3368856          DOI： 10.4161/cc.20535

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  10 in total

Review 1.  VEGF receptor signalling - in control of vascular function.

Authors:  Anna-Karin Olsson; Anna Dimberg; Johan Kreuger; Lena Claesson-Welsh
Journal:  Nat Rev Mol Cell Biol       Date:  2006-05       Impact factor: 94.444

2.  Grb-2-associated binder 1 (Gab1) regulates postnatal ischemic and VEGF-induced angiogenesis through the protein kinase A-endothelial NOS pathway.

Authors:  Yao Lu; Yan Xiong; Yingqing Huo; Jingyan Han; Xiao Yang; Rongli Zhang; De-Sheng Zhu; Stefan Klein-Hessling; Jun Li; Xiaoyu Zhang; Xiaofan Han; Yanli Li; Bin Shen; Yulong He; Masabumi Shibuya; Gen-Sheng Feng; Jincai Luo
Journal:  Proc Natl Acad Sci U S A       Date:  2011-01-31       Impact factor: 11.205

3.  The scaffolding adapter Gab1 mediates vascular endothelial growth factor signaling and is required for endothelial cell migration and capillary formation.

Authors:  Mélanie Laramée; Catherine Chabot; Monikca Cloutier; Raphaëlle Stenne; Marina Holgado-Madruga; Albert J Wong; Isabelle Royal
Journal:  J Biol Chem       Date:  2006-12-17       Impact factor: 5.157

4.  SH2 domains recognize specific phosphopeptide sequences.

Authors:  Z Songyang; S E Shoelson; M Chaudhuri; G Gish; T Pawson; W G Haser; F King; T Roberts; S Ratnofsky; R J Lechleider
Journal:  Cell       Date:  1993-03-12       Impact factor: 41.582

Review 5.  Signal transduction by vascular endothelial growth factor receptors.

Authors:  Sina Koch; Sònia Tugues; Xiujuan Li; Laura Gualandi; Lena Claesson-Welsh
Journal:  Biochem J       Date:  2011-07-15       Impact factor: 3.857

6.  R428, a selective small molecule inhibitor of Axl kinase, blocks tumor spread and prolongs survival in models of metastatic breast cancer.

Authors:  Sacha J Holland; Alison Pan; Christian Franci; Yuanming Hu; Betty Chang; Weiqun Li; Matt Duan; Allan Torneros; Jiaxin Yu; Thilo J Heckrodt; Jing Zhang; Pingyu Ding; Ayodele Apatira; Joanne Chua; Ralf Brandt; Polly Pine; Dane Goff; Rajinder Singh; Donald G Payan; Yasumichi Hitoshi
Journal:  Cancer Res       Date:  2010-02-09       Impact factor: 12.701

7.  The adaptor protein Gab1 couples the stimulation of vascular endothelial growth factor receptor-2 to the activation of phosphoinositide 3-kinase.

Authors:  Marie Dance; Alexandra Montagner; Armelle Yart; Bernard Masri; Yves Audigier; Bertrand Perret; Jean-Pierre Salles; Patrick Raynal
Journal:  J Biol Chem       Date:  2006-06-20       Impact factor: 5.157

Review 8.  Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases.

Authors:  Peter Carmeliet; Rakesh K Jain
Journal:  Nat Rev Drug Discov       Date:  2011-06       Impact factor: 84.694

Review 9.  Molecular mechanisms and clinical applications of angiogenesis.

Authors:  Peter Carmeliet; Rakesh K Jain
Journal:  Nature       Date:  2011-05-19       Impact factor: 49.962

10.  Axl is essential for VEGF-A-dependent activation of PI3K/Akt.

Authors:  Guo-Xiang Ruan; Andrius Kazlauskas
Journal:  EMBO J       Date:  2012-02-10       Impact factor: 11.598
  10 in total
  14 in total

1.  Quercetin alleviates pulmonary angiogenesis in a rat model of hepatopulmonary syndrome.

Authors:  X Li; Y Chen; L Wang; G Shang; C Zhang; Z Zhao; H Zhang; A Liu
Journal:  Braz J Med Biol Res       Date:  2016-07-04       Impact factor: 2.590

2.  The Robo4 cytoplasmic domain is dispensable for vascular permeability and neovascularization.

Authors:  Feng Zhang; Claudia Prahst; Thomas Mathivet; Laurence Pibouin-Fragner; Jiasheng Zhang; Gael Genet; Raymond Tong; Alexandre Dubrac; Anne Eichmann
Journal:  Nat Commun       Date:  2016-11-24       Impact factor: 14.919

3.  Mathematical Model Predicts Effective Strategies to Inhibit VEGF-eNOS Signaling.

Authors:  Qianhui Wu; Stacey D Finley
Journal:  J Clin Med       Date:  2020-04-26       Impact factor: 4.241

4.  WNK1 Enhances Migration and Invasion in Breast Cancer Models.

Authors:  Ankita B Jaykumar; Ji-Ung Jung; Pravat Kumar Parida; Tuyen T Dang; Chonlarat Wichaidit; Ashari Rashmi Kannangara; Svetlana Earnest; Elizabeth J Goldsmith; Gray W Pearson; Srinivas Malladi; Melanie H Cobb
Journal:  Mol Cancer Ther       Date:  2021-07-12       Impact factor: 6.009

Review 5.  Neurovascular regulation in diabetic retinopathy and emerging therapies.

Authors:  Liyang Ji; Hong Tian; Keith A Webster; Wei Li
Journal:  Cell Mol Life Sci       Date:  2021-07-07       Impact factor: 9.207

6.  Activation of the PI3K/Akt/mTOR/p70S6K pathway is involved in S100A4-induced viability and migration in colorectal cancer cells.

Authors:  Haiyan Wang; Liang Duan; Zhengyu Zou; Huan Li; Shimei Yuan; Xian Chen; Yunyuan Zhang; Xueru Li; Hui Sun; He Zha; Yan Zhang; Lan Zhou
Journal:  Int J Med Sci       Date:  2014-06-08       Impact factor: 3.738

7.  β2-Glycoprotein I Inhibits Vascular Endothelial Growth Factor-Induced Angiogenesis by Suppressing the Phosphorylation of Extracellular Signal-Regulated Kinase 1/2, Akt, and Endothelial Nitric Oxide Synthase.

Authors:  Wen-Chin Chiu; Tzeon-Jye Chiou; Meng-Ju Chung; An-Na Chiang
Journal:  PLoS One       Date:  2016-08-31       Impact factor: 3.240

8.  Computer Simulation of TSP1 Inhibition of VEGF-Akt-eNOS: An Angiogenesis Triple Threat.

Authors:  Hojjat Bazzazi; Yu Zhang; Mohammad Jafarnejad; Jeffrey S Isenberg; Brian H Annex; Aleksander S Popel
Journal:  Front Physiol       Date:  2018-05-30       Impact factor: 4.566

Review 9.  Phosphoinositide 3-Kinase/Akt Signaling and Redox Metabolism in Cancer.

Authors:  Nikos Koundouros; George Poulogiannis
Journal:  Front Oncol       Date:  2018-05-15       Impact factor: 6.244

10.  miR-22/KAT6B axis is a chemotherapeutic determiner via regulation of PI3k-Akt-NF-kB pathway in tongue squamous cell carcinoma.

Authors:  Yixue Gu; Hao Liu; Fangren Kong; Jiahui Ye; Xiaoting Jia; Zhijie Zhang; Nan Li; Jiang Yin; Guopei Zheng; Zhimin He
Journal:  J Exp Clin Cancer Res       Date:  2018-07-24
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