Literature DB >> 22645087

The role of Eph receptors in lens function and disease.

Alexander I Son1, Jeong Eun Park, RenPing Zhou.   

Abstract

Cataract is the single largest contributor to blindness in the world, with the disease having a strong genetic component. In recent years the Eph family of receptor tyrosine kinases has been identified as a key regulator in lens clarity. In this review we discuss the roles of the Eph receptors in lens biology and cataract development.

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Year:  2012        PMID： 22645087      PMCID： PMC4026180          DOI： 10.1007/s11427-012-4318-7

Source DB:  PubMed          Journal:  Sci China Life Sci        ISSN： 1674-7305            Impact factor:   6.038


  105 in total

1.  Eph receptors and ephrins restrict cell intermingling and communication.

Authors:  G Mellitzer; Q Xu; D G Wilkinson
Journal:  Nature       Date:  1999-07-01       Impact factor: 49.962

Review 2.  Cell signaling by receptor tyrosine kinases.

Authors:  J Schlessinger
Journal:  Cell       Date:  2000-10-13       Impact factor: 41.582

Review 3.  Mechanisms and functions of Eph and ephrin signalling.

Authors:  Klas Kullander; Rüdiger Klein
Journal:  Nat Rev Mol Cell Biol       Date:  2002-07       Impact factor: 94.444

4.  Ectopic EphA4 receptor induces posterior protrusions via FGF signaling in Xenopus embryos.

Authors:  Eui Kyun Park; Neil Warner; Yong-Sik Bong; David Stapleton; Ryu Maeda; Tony Pawson; Ira O Daar
Journal:  Mol Biol Cell       Date:  2004-01-23       Impact factor: 4.138

5.  A novel syndrome of paediatric cataract, dysmorphism, ectodermal features, and developmental delay in Australian Aboriginal family maps to 1p35.3-p36.32.

Authors:  Kathryn Hattersley; Kate J Laurie; Jan E Liebelt; Jozef Gecz; Shane R Durkin; Jamie E Craig; Kathryn P Burdon
Journal:  BMC Med Genet       Date:  2010-11-19       Impact factor: 2.103

6.  Gap junctional coupling in lenses lacking alpha3 connexin.

Authors:  X Gong; G J Baldo; N M Kumar; N B Gilula; R T Mathias
Journal:  Proc Natl Acad Sci U S A       Date:  1998-12-22       Impact factor: 11.205

7.  Transmembrane control of cadherin-mediated cell adhesion: a 94 kDa protein functionally associated with a specific region of the cytoplasmic domain of E-cadherin.

Authors:  A Nagafuchi; M Takeichi
Journal:  Cell Regul       Date:  1989-11

8.  Bfsp2 mutation found in mouse 129 strains causes the loss of CP49 and induces vimentin-dependent changes in the lens fibre cell cytoskeleton.

Authors:  Aileen Sandilands; Xin Wang; Aileen M Hutcheson; John James; Alan R Prescott; Alfred Wegener; Milos Pekny; Xiahou Gong; Roy A Quinlan
Journal:  Exp Eye Res       Date:  2004-01       Impact factor: 3.467

9.  Characterization of the association of connexins and ZO-1 in the lens.

Authors:  P A Nielsen; A Baruch; B N Giepmans; N M Kumar
Journal:  Cell Commun Adhes       Date:  2001

10.  Tyrosine phosphorylation regulates the adhesions of ras-transformed breast epithelia.

Authors:  M S Kinch; G J Clark; C J Der; K Burridge
Journal:  J Cell Biol       Date:  1995-07       Impact factor: 10.539
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  7 in total

1.  N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis.

Authors:  Caitlin M Logan; Suren Rajakaruna; Caitlin Bowen; Glenn L Radice; Michael L Robinson; A Sue Menko
Journal:  Dev Biol       Date:  2017-05-26       Impact factor: 3.582

2.  Formation of persistent hyperplastic primary vitreous in ephrin-A5-/- mice.

Authors:  Alexander I Son; Michal Sheleg; Margaret A Cooper; Yuhai Sun; Norman J Kleiman; Renping Zhou
Journal:  Invest Ophthalmol Vis Sci       Date:  2014-03-19       Impact factor: 4.799

3.  Breakdown of interlocking domains may contribute to formation of membranous globules and lens opacity in ephrin-A5(-/-) mice.

Authors:  Sondip Biswas; Alexander Son; Qili Yu; Renping Zhou; Woo-Kuen Lo
Journal:  Exp Eye Res       Date:  2015-11-28       Impact factor: 3.467

4.  Further analysis of the lens of ephrin-A5-/- mice: development of postnatal defects.

Authors:  Alexander I Son; Margaret A Cooper; Michal Sheleg; Yuhai Sun; Norman J Kleiman; Renping Zhou
Journal:  Mol Vis       Date:  2013-02-03       Impact factor: 2.367

5.  Association of the ephreceptor tyrosinekinase-type A2 (EPHA2) gene polymorphism rs3754334 with age-related cataract risk: a meta-analysis.

Authors:  Jin Yang; Jianfeng Luo; Peng Zhou; Qi Fan; Yi Luo; Yi Lu
Journal:  PLoS One       Date:  2013-08-16       Impact factor: 3.240

Review 6.  BCR Signaling Inhibitors: an Overview of Toxicities Associated with Ibrutinib and Idelalisib in Patients with Chronic Lymphocytic Leukemia.

Authors:  Lorenzo Falchi; Jessica M Baron; Carrie Anne Orlikowski; Alessandra Ferrajoli
Journal:  Mediterr J Hematol Infect Dis       Date:  2016-02-10       Impact factor: 2.576

7.  Association between polymorphisms of OGG1, EPHA2 and age-related cataract risk: a meta-analysis.

Authors:  Hongxu Zhang; Jianguang Zhong; Zhenyu Bian; Xiang Fang; You Peng; Yongping Hu
Journal:  BMC Ophthalmol       Date:  2016-09-29       Impact factor: 2.209
  7 in total

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