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Literature DB >> 22644704

Mechanism and stem-cell activity of 5-carboxycytosine decarboxylation determined by isotope tracing.

Stefan Schiesser¹, Benjamin Hackner, Toni Pfaffeneder, Markus Müller, Christian Hagemeier, Matthias Truss, Thomas Carell.

Abstract

Eraserhead: Stem cells seem to erase epigenetic information by decarboxylation of the newly discovered epigenetic base 5-carboxycytosine (caC; see picture). This reaction is likely to involve a nucleophilic attack of the C5-C6 double bond.

Entities: Chemical

Mesh：

Substances：

Year: 2012 PMID： 22644704 DOI： 10.1002/anie.201202583

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

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Cited

54 in total

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Journal: Cell Res Date: 2013-08-06 Impact factor: 25.617

Review 2. Toward pluripotency by reprogramming: mechanisms and application.

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Journal: Protein Cell Date: 2013-11 Impact factor: 14.870

3. Reversing DNA methylation: mechanisms, genomics, and biological functions.

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Review 4. Mechanism and function of oxidative reversal of DNA and RNA methylation.

Authors: Li Shen; Chun-Xiao Song; Chuan He; Yi Zhang
Journal: Annu Rev Biochem Date: 2014 Impact factor: 23.643

Review 5. Transcriptional and epigenetic mechanisms of cellular reprogramming to induced pluripotency.

Authors: Mark van den Hurk; Gunter Kenis; Cedric Bardy; Daniel L van den Hove; Fred H Gage; Harry W Steinbusch; Bart P Rutten
Journal: Epigenomics Date: 2016-07-15 Impact factor: 4.778

6. 5-Formylcytosine to cytosine conversion by C-C bond cleavage in vivo.

Authors: Katharina Iwan; René Rahimoff; Angie Kirchner; Fabio Spada; Arne S Schröder; Olesea Kosmatchev; Shqiponja Ferizaj; Jessica Steinbacher; Edris Parsa; Markus Müller; Thomas Carell
Journal: Nat Chem Biol Date: 2017-11-27 Impact factor: 15.040

Review 7. Genomics and epigenomics in rheumatic diseases: what do they provide in terms of diagnosis and disease management?

Authors: Patricia Castro-Santos; Roberto Díaz-Peña
Journal: Clin Rheumatol Date: 2017-07-20 Impact factor: 2.980