Literature DB >> 22641371

PABPN1 shuts down alternative poly(A) sites.

Martine Simonelig1.   

Abstract

Although overlooked for many years, alternative cleavage and polyadenylation (APA) is now emerging as a major mechanism of gene regulation. A recent study identifies poly(A)-binding protein nuclear 1 (PABPN1), a general factor of polyadenylation, as a suppressor of alternative poly(A) sites.

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Year:  2012        PMID： 22641371      PMCID： PMC3463261          DOI： 10.1038/cr.2012.86

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


  14 in total

1.  Stimulation of poly(A) polymerase through a direct interaction with the nuclear poly(A) binding protein allosterically regulated by RNA.

Authors:  Yvonne Kerwitz; Uwe Kühn; Hauke Lilie; Anne Knoth; Till Scheuermann; Henning Friedrich; Elisabeth Schwarz; Elmar Wahle
Journal:  EMBO J       Date:  2003-07-15       Impact factor: 11.598

2.  Poly(A) tail length is controlled by the nuclear poly(A)-binding protein regulating the interaction between poly(A) polymerase and the cleavage and polyadenylation specificity factor.

Authors:  Uwe Kühn; Miriam Gündel; Anne Knoth; Yvonne Kerwitz; Sabine Rüdel; Elmar Wahle
Journal:  J Biol Chem       Date:  2009-06-09       Impact factor: 5.157

3.  Levels of polyadenylation factor CstF-64 control IgM heavy chain mRNA accumulation and other events associated with B cell differentiation.

Authors:  Y Takagaki; J L Manley
Journal:  Mol Cell       Date:  1998-12       Impact factor: 17.970

Review 4.  Ending the message: poly(A) signals then and now.

Authors:  Nick J Proudfoot
Journal:  Genes Dev       Date:  2011-09-01       Impact factor: 11.361

5.  The polyadenylation factor CstF-64 regulates alternative processing of IgM heavy chain pre-mRNA during B cell differentiation.

Authors:  Y Takagaki; R L Seipelt; M L Peterson; J L Manley
Journal:  Cell       Date:  1996-11-29       Impact factor: 41.582

6.  Short GCG expansions in the PABP2 gene cause oculopharyngeal muscular dystrophy.

Authors:  B Brais; J P Bouchard; Y G Xie; D L Rochefort; N Chrétien; F M Tomé; R G Lafrenière; J M Rommens; E Uyama; O Nohira; S Blumen; A D Korczyn; P Heutink; J Mathieu; A Duranceau; F Codère; M Fardeau; G A Rouleau; A D Korcyn
Journal:  Nat Genet       Date:  1998-02       Impact factor: 38.330

7.  Tissue-specific autoregulation of Drosophila suppressor of forked by alternative poly(A) site utilization leads to accumulation of the suppressor of forked protein in mitotically active cells.

Authors:  F Juge; A Audibert; B Benoit; M Simonelig
Journal:  RNA       Date:  2000-11       Impact factor: 4.942

8.  Global patterns of tissue-specific alternative polyadenylation in Drosophila.

Authors:  Peter Smibert; Pedro Miura; Jakub O Westholm; Sol Shenker; Gemma May; Michael O Duff; Dayu Zhang; Brian D Eads; Joe Carlson; James B Brown; Robert C Eisman; Justen Andrews; Thomas Kaufman; Peter Cherbas; Susan E Celniker; Brenton R Graveley; Eric C Lai
Journal:  Cell Rep       Date:  2012-03-29       Impact factor: 9.423

9.  The nuclear poly(A)-binding protein interacts with the exosome to promote synthesis of noncoding small nucleolar RNAs.

Authors:  Jean-François Lemay; Annie D'Amours; Caroline Lemieux; Daniel H Lackner; Valérie G St-Sauveur; Jürg Bähler; François Bachand
Journal:  Mol Cell       Date:  2010-01-15       Impact factor: 17.970

10.  Autoregulation at the level of mRNA 3' end formation of the suppressor of forked gene of Drosophila melanogaster is conserved in Drosophila virilis.

Authors:  A Audibert; M Simonelig
Journal:  Proc Natl Acad Sci U S A       Date:  1998-11-24       Impact factor: 11.205
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  8 in total

Review 1.  Implications of polyadenylation in health and disease.

Authors:  Ana Curinha; Sandra Oliveira Braz; Isabel Pereira-Castro; Andrea Cruz; Alexandra Moreira
Journal:  Nucleus       Date:  2014-10-31       Impact factor: 4.197

2.  A decline in PABPN1 induces progressive muscle weakness in oculopharyngeal muscle dystrophy and in muscle aging.

Authors:  Seyed Yahya Anvar; Yotam Raz; Nisha Verway; Barbara van der Sluijs; Andrea Venema; Jelle J Goeman; John Vissing; Silvère M van der Maarel; Peter A C 't Hoen; Baziel G M van Engelen; Vered Raz
Journal:  Aging (Albany NY)       Date:  2013-06       Impact factor: 5.682

3.  Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair.

Authors:  Michal Gavish-Izakson; Bhagya Bhavana Velpula; Ran Elkon; Rosario Prados-Carvajal; Georgina D Barnabas; Alejandro Pineiro Ugalde; Reuven Agami; Tamar Geiger; Pablo Huertas; Yael Ziv; Yosef Shiloh
Journal:  Nucleic Acids Res       Date:  2018-01-25       Impact factor: 16.971

4.  Cleavage and polyadenylation: Ending the message expands gene regulation.

Authors:  Jonathan Neve; Radhika Patel; Zhiqiao Wang; Alastair Louey; André Martin Furger
Journal:  RNA Biol       Date:  2017-04-28       Impact factor: 4.652

5.  Regulation of Kv11.1 Isoform Expression by Polyadenylate Binding Protein Nuclear 1.

Authors:  Matthew R Stump; Rachel T Nguyen; Rachel H Drgastin; Delaney Search; Qiuming Gong; Zhengfeng Zhou
Journal:  Int J Mol Sci       Date:  2021-01-16       Impact factor: 5.923

Review 6.  Implications of Poly(A) Tail Processing in Repeat Expansion Diseases.

Authors:  Paweł Joachimiak; Adam Ciesiołka; Grzegorz Figura; Agnieszka Fiszer
Journal:  Cells       Date:  2022-02-15       Impact factor: 6.600

7.  Deep sequencing reveals a novel class of bidirectional promoters associated with neuronal genes.

Authors:  Hai Yang Hu; Liu He; Philipp Khaitovich
Journal:  BMC Genomics       Date:  2014-06-10       Impact factor: 3.969

8.  Differential genome-wide profiling of alternative polyadenylation sites in nasopharyngeal carcinoma by high-throughput sequencing.

Authors:  Ya-Fei Xu; Ying-Qing Li; Na Liu; Qing-Mei He; Xin-Ran Tang; Xin Wen; Xiao-Jing Yang; Ying Sun; Jun Ma; Ling-Long Tang
Journal:  J Biomed Sci       Date:  2018-10-23       Impact factor: 8.410
  8 in total

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