Literature DB >> 22639144

Functions, applications and production of 2-O-D-glucopyranosyl-L-ascorbic acid.

Ruizhi Han1, Long Liu, Jianghua Li, Guocheng Du, Jian Chen.   

Abstract

Vitamin C (VC) is an essential nutrient that cannot be synthesized by the human body. Due to its extreme instability, various VC derivatives have been developed in an attempt to improve stability while retaining the same biological activity. One of the most important VC derivatives, 2-O-D-glucopyranosyl-L-ascorbic acid (AA-2G), has attracted increasing attention in recent years with a wide range of applications in cosmetics, food, and medicine. In this mini-review, we first introduce the types and properties of different VC glycosyl derivatives. Next, we provide an overview of the functions and applications of AA-2G. Finally, we discuss in-depth the current status and future prospects of AA-2G production by biotransformation.

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Year:  2012        PMID: 22639144     DOI: 10.1007/s00253-012-4150-9

Source DB:  PubMed          Journal:  Appl Microbiol Biotechnol        ISSN: 0175-7598            Impact factor:   4.813


  12 in total

1.  Fusion of self-assembling amphipathic oligopeptides with cyclodextrin glycosyltransferase improves 2-O-D-glucopyranosyl-L-ascorbic acid synthesis with soluble starch as the glycosyl donor.

Authors:  Ruizhi Han; Jianghua Li; Hyun-dong Shin; Rachel R Chen; Long Liu; Guocheng Du; Jian Chen
Journal:  Appl Environ Microbiol       Date:  2014-08       Impact factor: 4.792

2.  Systems engineering of tyrosine 195, tyrosine 260, and glutamine 265 in cyclodextrin glycosyltransferase from Paenibacillus macerans to enhance maltodextrin specificity for 2-O-(D)-glucopyranosyl-(L)-ascorbic acid synthesis.

Authors:  Ruizhi Han; Long Liu; Hyun-Dong Shin; Rachel R Chen; Jianghua Li; Guocheng Du; Jian Chen
Journal:  Appl Environ Microbiol       Date:  2012-11-16       Impact factor: 4.792

3.  Enhanced production of α-cyclodextrin glycosyltransferase in Escherichia coli by systematic codon usage optimization.

Authors:  Hua Liu; Jianghua Li; Guocheng Du; Jingwen Zhou; Jian Chen
Journal:  J Ind Microbiol Biotechnol       Date:  2012-08-17       Impact factor: 3.346

4.  Iterative saturation mutagenesis of -6 subsite residues in cyclodextrin glycosyltransferase from Paenibacillus macerans to improve maltodextrin specificity for 2-O-D-glucopyranosyl-L-ascorbic acid synthesis.

Authors:  Ruizhi Han; Long Liu; Hyun-Dong Shin; Rachel R Chen; Jianghua Li; Guocheng Du; Jian Chen
Journal:  Appl Environ Microbiol       Date:  2013-09-27       Impact factor: 4.792

5.  Carbohydrate-binding module-cyclodextrin glycosyltransferase fusion enables efficient synthesis of 2-O-d-glucopyranosyl-l-ascorbic acid with soluble starch as the glycosyl donor.

Authors:  Ruizhi Han; Jianghua Li; Hyun-Dong Shin; Rachel R Chen; Guocheng Du; Long Liu; Jian Chen
Journal:  Appl Environ Microbiol       Date:  2013-03-15       Impact factor: 4.792

Review 6.  Targeting the redox balance in inflammatory skin conditions.

Authors:  Frank A D T G Wagener; Carine E Carels; Ditte M S Lundvig
Journal:  Int J Mol Sci       Date:  2013-04-26       Impact factor: 5.923

7.  Application of Transgalactosylation Activity of β-Galactosidase from Kluyveromyces lactis for the Synthesis of Ascorbic Acid Galactoside.

Authors:  Aleksandra Wojciechowska; Robert Klewicki; Michał Sójka; Katarzyna Grzelak-Błaszczyk
Journal:  Appl Biochem Biotechnol       Date:  2017-07-13       Impact factor: 2.926

8.  Heterologous expression of cyclodextrin glycosyltransferase from Paenibacillus macerans in Escherichia coli and its application in 2-O-α-D-glucopyranosyl-L-ascorbic acid production.

Authors:  Yujia Jiang; Jie Zhou; Ruofan Wu; Fengxue Xin; Wenming Zhang; Yan Fang; Jiangfeng Ma; Weiliang Dong; Min Jiang
Journal:  BMC Biotechnol       Date:  2018-08-31       Impact factor: 2.563

9.  Enhanced Antioxidant Activity under Biomimetic Settings of Ascorbic Acid Included in Halloysite Nanotubes.

Authors:  Andrea Baschieri; Riccardo Amorati; Tiziana Benelli; Laura Mazzocchetti; Emanuele D'Angelo; Luca Valgimigli
Journal:  Antioxidants (Basel)       Date:  2019-01-27

Review 10.  Comprehensive study on transglycosylation of CGTase from various sources.

Authors:  Chin Hui Lim; Babak Rasti; Joko Sulistyo; Mansoor Abdul Hamid
Journal:  Heliyon       Date:  2021-02-20
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