| Literature DB >> 22638841 |
Abstract
Chronic urticaria is defined as case of spontaneous wheals and/or angioedema persisting for a period of at least six weeks. The disease has an average duration of three to five years and is strongly associated with a decrease of quality of life and performance. Current international guidelines recommend the use of non-sedating antihistamines as the first choice in therapy and up-dosing these up to fourfold in cases of non-response. Alternative treatments for the afflicted who do not respond to antihistamine-treatment are also available but are not approved for use on urticaria.Entities:
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Year: 2012 PMID: 22638841 DOI: 10.1007/s11882-012-0270-7
Source DB: PubMed Journal: Curr Allergy Asthma Rep ISSN: 1529-7322 Impact factor: 4.806