| Literature DB >> 22633486 |
Abstract
RNA silencing requires assembly of an effector complex, RNA-induced silencing complex (RISC), composed of a small RNA and the Ago protein. In this issue of Molecular Cell, Liu et al. (2012) provide insights of miRNP/RISC assembly pathways in mammals, using an in vitro human RISC assembly assay programmed by pre-miRNAs.Entities:
Year: 2012 PMID: 22633486 DOI: 10.1016/j.molcel.2012.05.012
Source DB: PubMed Journal: Mol Cell ISSN: 1097-2765 Impact factor: 17.970