Literature DB >> 22623628

A bioresorbable osteosynthesis device can induce an earlier sternal fusion after median sternotomy.

Tomohiro Tsunekawa1, Akihiko Usui, Hideki Oshima, Shinnichi Mizutani, Yoshimori Araki, Noritaka Okada, Yuichi Ueda.   

Abstract

OBJECTIVES: We examined the impact of the bioresorbable osteosynthesis sternal pin (Super Fixsorb 30) on sternal healing after median sternotomy.
METHODS: Sixty-three patients who underwent aortic surgery through median sternotomy between January 2006 and March 2009 were analysed. Sternal pins were utilized in 36 patients in addition to the standard closure of the sternum with Ethibond sutures (Group A), and 27 patients received no pins with the standard Ethibond sternal closure (Group B). The occurrence of transverse sternal dehiscence, anterior-posterior displacement and complete fusion of the sternum were evaluated by a computed tomography scan. The cross-sectional cortical bone density area (CBDA) of the sternum was examined to evaluate the osteoconductivity of the sternal pin over a 12-month period.
RESULTS: There was no sternal displacement (0%) observed in Group A at discharge. Meanwhile, five displacements (18.5%) were observed in Group B (P = 0.007). The complete sternal fusion rates at 12 months postoperatively were 100% in Group A, and 21.6% in Group B (P < 0.001). A significant increase in the CBDA was observed in Group A (P < 0.001; between CBDA at discharge and 12 months postoperatively).
CONCLUSIONS: The Super Fixsorb 30 sternal pin reduced an anterior-posterior sternal displacement and facilitated an earlier sternal fusion. The pin may have the potential to promote osteogenesis.

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Year:  2012        PMID: 22623628      PMCID: PMC3422921          DOI: 10.1093/icvts/ivs151

Source DB:  PubMed          Journal:  Interact Cardiovasc Thorac Surg        ISSN: 1569-9285


  10 in total

1.  Sternal instability after midline sternotomy.

Authors:  F Robicsek; A Fokin; J Cook; D Bhatia
Journal:  Thorac Cardiovasc Surg       Date:  2000-02       Impact factor: 1.827

2.  Bioresorbable devices made of forged composites of hydroxyapatite (HA) particles and poly-L-lactide (PLLA): Part I. Basic characteristics.

Authors:  Y Shikinami; M Okuno
Journal:  Biomaterials       Date:  1999-05       Impact factor: 12.479

3.  Sternal closure with reabsorbable pin and cord in pediatric-less invasive cardiac surgery.

Authors:  Hiroshi Oiwa; Ryoichi Ishida; Kenichi Sudo
Journal:  Ann Thorac Surg       Date:  2004-07       Impact factor: 4.330

4.  Effective median sternotomy closure in high-risk open heart patients.

Authors:  Eugene L Bek; Kwok L Yun; Gary S Kochamba; Thomas A Pfeffer
Journal:  Ann Thorac Surg       Date:  2010-04       Impact factor: 4.330

5.  The complete process of bioresorption and bone replacement using devices made of forged composites of raw hydroxyapatite particles/poly l-lactide (F-u-HA/PLLA).

Authors:  Yasuo Shikinami; Yoshitaka Matsusue; Takashi Nakamura
Journal:  Biomaterials       Date:  2005-09       Impact factor: 12.479

6.  Clinical studies of bioabsorbable poly-L-lactide sternal coaptation pins.

Authors:  T Tanaka; Y Okawa; N Ishida; M Toyama; M Hashimoto; K Matsumoto
Journal:  J Cardiovasc Surg (Torino)       Date:  2001-12       Impact factor: 1.888

7.  Bioresorbable devices made of forged composites of hydroxyapatite (HA) particles and poly L-lactide (PLLA). Part II: practical properties of miniscrews and miniplates.

Authors:  Y Shikinami; M Okuno
Journal:  Biomaterials       Date:  2001-12       Impact factor: 12.479

8.  Reinforced closure of the sternum with absorbable pins for high-risk patients.

Authors:  Masatsugu Hamaji; Yasuto Sakaguchi; Mitsuhiko Matsuda; Satoshi Kono
Journal:  Interact Cardiovasc Thorac Surg       Date:  2009-07-02

9.  Usefulness of osteosynthesis device made of hydroxyapatite-poly-L-lactide composites in port-access cardiac surgery.

Authors:  Tsutomu Ito; Mikihiko Kudo; Ryohei Yozu
Journal:  Ann Thorac Surg       Date:  2008-12       Impact factor: 4.330

10.  Primary sternal plating in high-risk patients prevents mediastinitis.

Authors:  David H Song; Robert F Lohman; John D Renucci; Valluvan Jeevanandam; Jai Raman
Journal:  Eur J Cardiothorac Surg       Date:  2004-08       Impact factor: 4.191

  10 in total
  6 in total

1.  A comparative study of two types of sternal pins used for sternal closure: poly-L-lactide sternal pins versus uncalcined hydroxyapatite poly-L-lactide sternal pins.

Authors:  Xian-ming Fu; Hideki Oshima; Yoshimori Araki; Yuji Narita; Masato Mutsuga; Noritaka Okada; Tomohiro Tsunekawa; Akihiko Usui
Journal:  J Artif Organs       Date:  2013-08-31       Impact factor: 1.731

Review 2.  Sternal wound closure in the current era: the need of a tailored approach.

Authors:  Antonio Nenna; Francesco Nappi; Jennifer Dougal; Umberto Satriano; Camilla Chello; Ciro Mastroianni; Mario Lusini; Massimo Chello; Cristiano Spadaccio
Journal:  Gen Thorac Cardiovasc Surg       Date:  2019-09-17

3.  Sternal closure with absorbable pins and cords in general thoracic surgery.

Authors:  Mitsuaki Kawashima; Atsushi Sano; Makoto Tanaka
Journal:  Surg Today       Date:  2014-11-29       Impact factor: 2.549

4.  Reabsorbable Pins can Reinforce an Early Sternal Stability After Median Sternotomy in Young Children with Congenital Heart Disease.

Authors:  Chengming Fan; Mi Tang; Sijie Wu; Shuwen Yuan; Anton V Borovjagin; Jinfu Yang
Journal:  Pediatr Cardiol       Date:  2019-09-23       Impact factor: 1.655

5.  Successful Surgical Fixation Using Bio-Absorbable Plates for Frail Chest in a Severe Osteoporotic Octogenarian.

Authors:  Ryuichi Waseda; Isao Matsumoto; Yasuhiko Tatsuzawa; Akinori Iwasaki
Journal:  Ann Thorac Cardiovasc Surg       Date:  2018-03-22       Impact factor: 1.520

6.  Clinical assessment of efficacy of poly-L-lactide sternal pin on sternal stability and post-operative pain: a prospective randomized trial in cardiovascular surgery.

Authors:  Shingo Takahara; Konosuke Sasaki; Takeshi Saito; Kei Sakuma; Hidenori Fujiwara; Ichiro Yoshioka; Kiichiro Kumagai; Wenyu Sun; Kei Takase; Yoshikatsu Saiki
Journal:  J Thorac Dis       Date:  2022-01       Impact factor: 2.895

  6 in total

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