Literature DB >> 22618269

Prevalence of osteoporotic fracture risk factors and antiosteoporotic treatments in the Valencia region, Spain. The baseline characteristics of the ESOSVAL cohort.

J Sanfélix-Genovés1, G Sanfélix-Gimeno, S Peiró, I Hurtado, C Fluixà, A Fuertes, J C Campos, V Giner, C Baixauli.   

Abstract

UNLABELLED: This study provides information on the prevalence of the most important risk factors for osteoporosis and osteoporotic fracture in a large sample of women and men from the Valencia region and also provides the FRAX 10-year major and hip fracture risks for this population, as well as data about the use of diagnostic tests and antiosteoporotic treatments.
INTRODUCTION: The purpose of this study was to describe demographic characteristics, osteoporosis risk factors, the 10-year risk of osteoporotic fracture, and the use of densitometry and antiosteoporotic treatments in the Valencia region, Spain.
METHODS: A cross-sectional study using the ESOSVAL cohort baseline data was conducted. We analyze the data from 5,310 women and 5,725 men aged 50 and over who attended to 272 collaborating primary care centers in 2009-2010. We collected the demographic, anthropometric, clinical, and pharmacy data from the electronic medical record.
RESULTS: The mean age of participants was 64.3 years old for women and 65.6 years old for men. The most frequent fracture risk factors were sedentary life (22.2 %) and previous fracture (15.8 %) in women and low calcium intake (21.4 %) and current smoker (20.9 %) in men. According to FRAX(®), the 10-year risk of presenting a major fracture was 5.5 % for the women and 2.8 % for the men. The 10-year risk for hip fracture was 1.9 and 1.1 % for the women and the men, respectively; 23.8 % of the women and 5.2 % of the men had a densitometry test, 27.7 % of the women and 3.5 % of the men were taking calcium and/or vitamin D supplements, and 28.2 % of the women (22.0 % in the 50-64 age group) and 2.3 % of the men were taking antiosteoporotic drugs.
CONCLUSIONS: The prevalence of certain fracture risk factors not included in the FRAX tool (sedentary life, falls, low calcium intake) is high. In young women, their low risks estimated by FRAX contrast with the high figures for densitometry testing and treatment.

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Year:  2012        PMID: 22618269     DOI: 10.1007/s00198-012-2018-6

Source DB:  PubMed          Journal:  Osteoporos Int        ISSN: 0937-941X            Impact factor:   4.507


  38 in total

1.  2010 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada: summary.

Authors:  Alexandra Papaioannou; Suzanne Morin; Angela M Cheung; Stephanie Atkinson; Jacques P Brown; Sidney Feldman; David A Hanley; Anthony Hodsman; Sophie A Jamal; Stephanie M Kaiser; Brent Kvern; Kerry Siminoski; William D Leslie
Journal:  CMAJ       Date:  2010-10-12       Impact factor: 8.262

2.  Joint Official Positions of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX(®). Executive Summary of the 2010 Position Development Conference on Interpretation and use of FRAX® in clinical practice.

Authors:  Didier B Hans; John A Kanis; Sanford Baim; John P Bilezikian; Neil Binkley; Jane A Cauley; Juliet E Compston; Cyrus Cooper; Bess Dawson-Hughes; Ghada El-Hajj Fuleihan; William D Leslie; E Michael Lewiecki; Marjorie M Luckey; Eugene V McCloskey; Socrates E Papapoulos; Catalina Poiana; René Rizzoli
Journal:  J Clin Densitom       Date:  2011 Jul-Sep       Impact factor: 2.617

3.  American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the diagnosis and treatment of postmenopausal osteoporosis.

Authors:  Nelson B Watts; John P Bilezikian; Pauline M Camacho; Susan L Greenspan; Steven T Harris; Stephen F Hodgson; Michael Kleerekoper; Marjorie M Luckey; Michael R McClung; Rachel Pessah Pollack; Steven M Petak
Journal:  Endocr Pract       Date:  2010 Nov-Dec       Impact factor: 3.443

4.  [Usefulness of FRAX tool for the management of osteoporosis in the Spanish female population].

Authors:  Rafael Azagra Ledesma; Daniel Prieto-Alhambra; Gloria Encabo Duró; Enrique Casado Burgos; Amada Aguyé Batista; Adolfo Díez-Pérez
Journal:  Med Clin (Barc)       Date:  2011-02-24       Impact factor: 1.725

5.  An assessment tool for predicting fracture risk in postmenopausal women.

Authors:  D M Black; M Steinbuch; L Palermo; P Dargent-Molina; R Lindsay; M S Hoseyni; O Johnell
Journal:  Osteoporos Int       Date:  2001       Impact factor: 4.507

6.  Assessment of individual fracture risk: FRAX and beyond.

Authors:  Joop P W van den Bergh; Tineke A C M van Geel; Willem F Lems; Piet P Geusens
Journal:  Curr Osteoporos Rep       Date:  2010-09       Impact factor: 5.096

7.  Impact of a multifaceted intervention to improve the clinical management of osteoporosis. The ESOSVAL-F study.

Authors:  José Sanfélix-Genovés; Salvador Peiró; Gabriel Sanfélix-Gimeno; Isabel Hurtado; Manuel Pascual de la Torre; José Luis Trillo-Mata; Vicente Giner-Ruiz
Journal:  BMC Health Serv Res       Date:  2010-10-21       Impact factor: 2.655

8.  FRAX and the assessment of fracture probability in men and women from the UK.

Authors:  J A Kanis; O Johnell; A Oden; H Johansson; E McCloskey
Journal:  Osteoporos Int       Date:  2008-02-22       Impact factor: 4.507

9.  Adherence to and appropriateness of anti-osteoporotic treatments in patients aged 50 and over in the Valencia Region (Spain). The ESOSVAL-AD study.

Authors:  Gabriel Sanfélix-Gimeno; José Sanfélix-Genovés; Salvador Peiró; Isabel Hurtado; José Luis Trillo; Ruth Usó; Vicente Giner Ruiz; Manuel Pascual de la Torre; Inmaculada Ferreros
Journal:  BMC Musculoskelet Disord       Date:  2011-08-03       Impact factor: 2.362

10.  Prediction of absolute risk of fragility fracture at 10 years in a Spanish population: validation of the WHO FRAX ™ tool in Spain.

Authors:  Rafael Azagra; Genís Roca; Gloria Encabo; Daniel Prieto; Amada Aguyé; Marta Zwart; Sílvia Güell; Núria Puchol; Emili Gene; Enrique Casado; Pilar Sancho; Sílvia Solà; Pere Torán; Milagros Iglesias; Victòria Sabaté; Francesc López-Expósito; Sergio Ortiz; Yolanda Fernandez; Adolf Diez-Perez
Journal:  BMC Musculoskelet Disord       Date:  2011-01-28       Impact factor: 2.362

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  13 in total

1.  Cost-effectiveness of Virtual Bone Strength Testing in Osteoporosis Screening Programs for Postmenopausal Women in the United States.

Authors:  Christoph A Agten; Austin J Ramme; Stella Kang; Stephen Honig; Gregory Chang
Journal:  Radiology       Date:  2017-06-14       Impact factor: 11.105

2.  [If you find yourself in a hole the first thing to do is stop digging].

Authors:  Salvador Peiró
Journal:  Aten Primaria       Date:  2012-09-13       Impact factor: 1.137

3.  Prevalence of osteoporosis in the ESOSVAL cohort: reply to the comment by Pedrera-Zamorano et al.

Authors:  J Sanfélix-Genovés; I Hurtado; G Sanfélix-Gimeno; S Peiró
Journal:  Osteoporos Int       Date:  2012-09-29       Impact factor: 4.507

4.  Comment on Sanfélix-Genovés et al.: Prevalence of osteoporotic fracture risk factors and antiosteoporotic treatments in the Valencia region, Spain. The baseline characteristics of the ESOSVAL cohort.

Authors:  J D Pedrera-Zamorano; J M Lavado-Garcia; J M Moran
Journal:  Osteoporos Int       Date:  2012-09-29       Impact factor: 4.507

5.  Overuse and Underuse of Antiosteoporotic Treatments According to Highly Influential Osteoporosis Guidelines: A Population-Based Cross-Sectional Study in Spain.

Authors:  Gabriel Sanfélix-Gimeno; Isabel Hurtado; José Sanfélix-Genovés; Cristóbal Baixauli-Pérez; Clara L Rodríguez-Bernal; Salvador Peiró
Journal:  PLoS One       Date:  2015-08-28       Impact factor: 3.240

6.  Variation in Antiosteoporotic Drug Prescribing and Spending Across Spain. A Population-Based Ecological Cross-Sectional Study.

Authors:  Gabriel Sanfélix-Gimeno; Julián Librero-López; Gracia Modroño-Riaño; Salvador Peiró; Clara L Rodríguez-Bernal
Journal:  Front Pharmacol       Date:  2018-04-13       Impact factor: 5.810

7.  Variations in osteoporosis medication utilization. A population-based ecological cross-sectional study in the region of Valencia, Spain.

Authors:  Gabriel Sanfélix-Gimeno; María-Lirios Juliá-Sanchis; Julián Librero; Salvador Peiró; Aníbal García-Sempere
Journal:  PLoS One       Date:  2018-06-21       Impact factor: 3.240

8.  Metabolic bone disease in patients diagnosed with inflammatory bowel disease from Spain.

Authors:  José Miranda-Bautista; Cristina Verdejo; Alicia Díaz-Redondo; Irene Bretón; José M Bellón; María Dolores Pérez-Valderas; Aránzazu Caballero-Marcos; Marta de Dios-Lascuevas; Elena González-Río; Cristina García-Sánchez; Ignacio Marín-Jiménez; Rafael Bañares; Luis Menchén
Journal:  Therap Adv Gastroenterol       Date:  2019-07-31       Impact factor: 4.409

Review 9.  Identifying and managing patients at high risk for fractures: conclusions from the second Spanish multidisciplinary forum-parathyroid hormone use in osteoporotic patients at high risk for fractures.

Authors:  Esteban Jódar Gimeno
Journal:  Drugs R D       Date:  2012-12-01

10.  Rationale of the Spanish FRAX model in decision-making for predicting osteoporotic fractures: an update of FRIDEX cohort of Spanish women.

Authors:  Rafael Azagra; Marta Zwart; Gloria Encabo; Amada Aguyé; Juan Carlos Martin-Sánchez; Nuria Puchol-Ruiz; Paula Gabriel-Escoda; Sergio Ortiz-Alinque; Emilio Gené; Milagros Iglesias; David Moriña; Miguel Angel Diaz-Herrera; Mireia Utzet; Josep Maria Manresa
Journal:  BMC Musculoskelet Disord       Date:  2016-06-17       Impact factor: 2.362

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