Literature DB >> 22610943

Burden of cancers in the valley of Kashmir: 5 year epidemiological study reveals a different scenario.

Arshad A Pandith1, Mushtaq A Siddiqi.   

Abstract

Cancer is a major burden worldwide but there are marked geographical variations in frequency and incidence overall. The aim of this study was to find the frequency and distribution of commonly occurring cancers in Kashmir, with particular emphasis on urinary bladder cancer. A total of 4,407 cases of histologically confirmed new cancer cases were registered at the Medical Records Department (MRD) of SKIMS from a period between January, 2005 and April 2010. Among 4407 cancers, 2,457 (55.7 %) were men and 1,950 (44.3 %) were women. Stomach cancer is the leading one with an average frequency of 19.2 % followed by esophagus and lung as 16.5 % and 14.6 %, respectively. Stomach (23 %) and lung (21 %) are the leading cancers in men while as esophageal cancer tops (18.3 %) in women followed by breast cancer (16.6 %). This distribution of cancer types is strikingly different from that in the rest of India where oropharyngeal cancer is most common form. Among urinogenital cancers, bladder cancer was observed to primarily affect Kashmiri population (5.9 %) followed by prostate cancer (2.1 %) and renal carcinoma (1.1 %). We conclude that Kashmir is a very high risk area of most commonly occurring cancers particularly cancers of gastrointestinal tract which comprise more than half the frequency of all the cancers.

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Year:  2012        PMID: 22610943     DOI: 10.1007/s13277-012-0418-z

Source DB:  PubMed          Journal:  Tumour Biol        ISSN: 1010-4283


  20 in total

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Journal:  Cancer Lett       Date:  1988-02       Impact factor: 8.679

5.  Activated H-ras gene mutations in transitional cell carcinoma of urinary bladder in a Kashmiri population.

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  14 in total

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4.  Quantitative assessment of the association between glutathione S-transferase P1 Ile105Val polymorphism and bladder cancer risk.

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5.  MGMT gene silencing by promoter hypermethylation in gastric cancer in a high incidence area.

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6.  The prognostic value of Smad4 mRNA in patients with prostate cancer.

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Authors:  Hongtuan Zhang; Qiang Wei; Ranlu Liu; Shiyong Qi; Peihe Liang; Can Qi; Andi Wang; Bin Sheng; Liang Li; Yong Xu
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8.  Epidemiology of Cancers in Kashmir, India: An Analysis of Hospital Data.

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10.  Prognostic Implication of BCR-ABL Fusion Transcript Variants in Chronic Myeloid Leukemia (CML) Treated with Imatinib.zzm321990A First of Its Kind Study on CML Patients of Kashmir

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