OBJECTIVE: To investigate demographic, socioeconomic, lifestyle, and medical factors that might predispose women to cervical human papillomavirus (HPV) infection. METHOD: A cross-sectional population-based study was performed. Women aged 18-64 years who attended selected obstetrics and gynecology or sexually transmitted disease (STD) clinics in mainland Portugal between February 2008 and March 2009 were recruited, according to an age-stratified sampling strategy. Liquid-based cytology samples were analyzed centrally for HPV genotype and for cytologic features. Univariate and multivariate logistic regression analyses identified risk factors for HPV infection. RESULTS: Among the 2326 women evaluated, the crude prevalence of HPV infection was 19.4%. Lifetime number of sexual partners was a strong predictor of HPV infection (odds ratio 5.44 for 5-10 partners versus 1 partner; P<0.001). Other risk factors were young age (particularly among women aged 20-24 years; P<0.001); country of birth other than mainland Portugal (P=0.002); education up to secondary school level (P=0.010); smoking history (≤ 10 years; P=0.004); and any STD in the past 12 months (P=0.052). CONCLUSION: Data from the present study may aid identification of women at increased risk of HPV infection and target prevention strategies. TRIAL REGISTRATION: National Commission of Data Protection (CNPD) registration number 5346/2007; Sanofi Pasteur MSD study number HPV-E05.
OBJECTIVE: To investigate demographic, socioeconomic, lifestyle, and medical factors that might predispose women to cervical human papillomavirus (HPV) infection. METHOD: A cross-sectional population-based study was performed. Women aged 18-64 years who attended selected obstetrics and gynecology or sexually transmitted disease (STD) clinics in mainland Portugal between February 2008 and March 2009 were recruited, according to an age-stratified sampling strategy. Liquid-based cytology samples were analyzed centrally for HPV genotype and for cytologic features. Univariate and multivariate logistic regression analyses identified risk factors for HPV infection. RESULTS: Among the 2326 women evaluated, the crude prevalence of HPV infection was 19.4%. Lifetime number of sexual partners was a strong predictor of HPV infection (odds ratio 5.44 for 5-10 partners versus 1 partner; P<0.001). Other risk factors were young age (particularly among women aged 20-24 years; P<0.001); country of birth other than mainland Portugal (P=0.002); education up to secondary school level (P=0.010); smoking history (≤ 10 years; P=0.004); and any STD in the past 12 months (P=0.052). CONCLUSION: Data from the present study may aid identification of women at increased risk of HPV infection and target prevention strategies. TRIAL REGISTRATION: National Commission of Data Protection (CNPD) registration number 5346/2007; Sanofi Pasteur MSD study number HPV-E05.
Authors: Karl Ulrich Petry; Alexander Luyten; Annika Justus; Angelika Iftner; Sarah Strehlke; Axel Reinecke-Lüthge; Elisabeth Grunwald; Renate Schulze-Rath; Thomas Iftner Journal: BMC Infect Dis Date: 2013-03-13 Impact factor: 3.090
Authors: Andréia Rodrigues Gonçalves Ayres; Gulnar Azevedo E Silva; Maria Teresa Bustamante Teixeira; Kristiane de Castro Dias Duque; Maria Lúcia Salim Miranda Machado; Carmen Justina Gamarra; José Eduardo Levi Journal: Rev Saude Publica Date: 2017-10-05 Impact factor: 2.106
Authors: Miguel Andujar; Esther Roura; Alejandra Torres; Begoña Vega; Marta Pavcovich; Miguel Angel Sanchez; Amina Lubrano; Jose Luis Trujillo; Lucia Almeida; Milagros Santana; Rosaura Hurtado; Octavio Arencibia; Virginia Benito; Norberto Medina; Sonia Carballo; Maria Del Carmen Camacho; Arancha Ruiz Del Pozo; Alfoso Quesada; Eduardo Salido; Silvia de Sanjosé; Laia Bruni Journal: BMJ Open Date: 2020-09-24 Impact factor: 2.692