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Literature DB >> 22596190

Teaching the design principles of metabolism.

Joshua D Rabinowitz¹, Livia Vastag.

Abstract

Entities: Chemical Disease Gene Species

Mesh：

Substances：
Pyruvate Kinase
Glucose

Year: 2012 PMID： 22596190 PMCID： PMC4084555 DOI： 10.1038/nchembio.969

Source DB: PubMed Journal: Nat Chem Biol ISSN： 1552-4450 Impact factor: 15.040

× No keyword cloud information.

21 in total

1. A sampling of the yeast proteome.

Authors: B Futcher; G I Latter; P Monardo; C S McLaughlin; J I Garrels
Journal: Mol Cell Biol Date: 1999-11 Impact factor: 4.272

Review 2. Metabolomics--the link between genotypes and phenotypes.

Authors: Oliver Fiehn
Journal: Plant Mol Biol Date: 2002-01 Impact factor: 4.076

3. Escherichia coli K-12 undergoes adaptive evolution to achieve in silico predicted optimal growth.

Authors: Rafael U Ibarra; Jeremy S Edwards; Bernhard O Palsson
Journal: Nature Date: 2002-11-14 Impact factor: 49.962

4. Global reconstruction of the human metabolic network based on genomic and bibliomic data.

Authors: Natalie C Duarte; Scott A Becker; Neema Jamshidi; Ines Thiele; Monica L Mo; Thuy D Vo; Rohith Srivas; Bernhard Ø Palsson
Journal: Proc Natl Acad Sci U S A Date: 2007-01-31 Impact factor: 11.205

Review 5. The growing scope of applications of genome-scale metabolic reconstructions using Escherichia coli.

Authors: Adam M Feist; Bernhard Ø Palsson
Journal: Nat Biotechnol Date: 2008-06 Impact factor: 54.908

6. The game of the pentose phosphate cycle: a mathematical approach to study the optimization in design of metabolic pathways during evolution.

Authors: E Meléndez-Hevia
Journal: Biomed Biochim Acta Date: 1990

Review 7. Functions of the gene products of Escherichia coli.

Authors: M Riley
Journal: Microbiol Rev Date: 1993-12

8. The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth.

Authors: Heather R Christofk; Matthew G Vander Heiden; Marian H Harris; Arvind Ramanathan; Robert E Gerszten; Ru Wei; Mark D Fleming; Stuart L Schreiber; Lewis C Cantley
Journal: Nature Date: 2008-03-13 Impact factor: 49.962

Review 9. Understanding the Warburg effect: the metabolic requirements of cell proliferation.

Authors: Matthew G Vander Heiden; Lewis C Cantley; Craig B Thompson
Journal: Science Date: 2009-05-22 Impact factor: 47.728

10. Impact of limited solvent capacity on metabolic rate, enzyme activities, and metabolite concentrations of S. cerevisiae glycolysis.

Authors: Alexei Vazquez; Marcio A de Menezes; Albert-László Barabási; Zoltan N Oltvai
Journal: PLoS Comput Biol Date: 2008-10-10 Impact factor: 4.475

7 in total

Teaching the design principles of metabolism.

1. A sampling of the yeast proteome.

Review 2. Metabolomics--the link between genotypes and phenotypes.

3. Escherichia coli K-12 undergoes adaptive evolution to achieve in silico predicted optimal growth.

4. Global reconstruction of the human metabolic network based on genomic and bibliomic data.

Review 5. The growing scope of applications of genome-scale metabolic reconstructions using Escherichia coli.

6. The game of the pentose phosphate cycle: a mathematical approach to study the optimization in design of metabolic pathways during evolution.

Review 7. Functions of the gene products of Escherichia coli.

8. The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth.

Review 9. Understanding the Warburg effect: the metabolic requirements of cell proliferation.

10. Impact of limited solvent capacity on metabolic rate, enzyme activities, and metabolite concentrations of S. cerevisiae glycolysis.

1. Optimizing genome-scale network reconstructions.

2. Metabolism: A new layer of glycolysis.

3. Searching for principles of microbial physiology.

4. Glycolytic Metabolism Plays a Functional Role in Regulating Human Pluripotent Stem Cell State.

5. New concepts in feedback regulation of glucose metabolism.

6. Flux-dependent graphs for metabolic networks.

7. Analysis of steady-state carbon tracer experiments using akaike information criteria.