Literature DB >> 22596150

Structural biology: How opioid drugs bind to receptors.

Marta Filizola, Lakshmi A Devi.   

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Year:  2012        PMID： 22596150      PMCID： PMC3589518          DOI： 10.1038/485314a

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  12 in total

1.  Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists.

Authors:  Beili Wu; Ellen Y T Chien; Clifford D Mol; Gustavo Fenalti; Wei Liu; Vsevolod Katritch; Ruben Abagyan; Alexei Brooun; Peter Wells; F Christopher Bi; Damon J Hamel; Peter Kuhn; Tracy M Handel; Vadim Cherezov; Raymond C Stevens
Journal:  Science       Date:  2010-10-07       Impact factor: 47.728

2.  Morphine-like opiates selectively antagonize receptor-arrestin interactions.

Authors:  Paola Molinari; Vanessa Vezzi; Maria Sbraccia; Cristina Grò; Daniela Riitano; Caterina Ambrosio; Ida Casella; Tommaso Costa
Journal:  J Biol Chem       Date:  2010-02-26       Impact factor: 5.157

3.  Two distinct conformations of helix 6 observed in antagonist-bound structures of a beta1-adrenergic receptor.

Authors:  Rouslan Moukhametzianov; Tony Warne; Patricia C Edwards; Maria J Serrano-Vega; Andrew G W Leslie; Christopher G Tate; Gebhard F X Schertler
Journal:  Proc Natl Acad Sci U S A       Date:  2011-05-03       Impact factor: 11.205

4.  Recent progress in the structure determination of GPCRs, a membrane protein family with high potential as pharmaceutical targets.

Authors:  Vadim Cherezov; Enrique Abola; Raymond C Stevens
Journal:  Methods Mol Biol       Date:  2010

5.  Structure of a beta1-adrenergic G-protein-coupled receptor.

Authors:  Tony Warne; Maria J Serrano-Vega; Jillian G Baker; Rouslan Moukhametzianov; Patricia C Edwards; Richard Henderson; Andrew G W Leslie; Christopher G Tate; Gebhard F X Schertler
Journal:  Nature       Date:  2008-06-25       Impact factor: 49.962

6.  GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function.

Authors:  Daniel M Rosenbaum; Vadim Cherezov; Michael A Hanson; Søren G F Rasmussen; Foon Sun Thian; Tong Sun Kobilka; Hee-Jung Choi; Xiao-Jie Yao; William I Weis; Raymond C Stevens; Brian K Kobilka
Journal:  Science       Date:  2007-10-25       Impact factor: 47.728

7.  Receptor heteromerization and drug discovery.

Authors:  Raphael Rozenfeld; Lakshmi A Devi
Journal:  Trends Pharmacol Sci       Date:  2010-01-07       Impact factor: 14.819

8.  Crystal structure of the µ-opioid receptor bound to a morphinan antagonist.

Authors:  Aashish Manglik; Andrew C Kruse; Tong Sun Kobilka; Foon Sun Thian; Jesper M Mathiesen; Roger K Sunahara; Leonardo Pardo; William I Weis; Brian K Kobilka; Sébastien Granier
Journal:  Nature       Date:  2012-03-21       Impact factor: 49.962

9.  Structure of the human κ-opioid receptor in complex with JDTic.

Authors:  Huixian Wu; Daniel Wacker; Mauro Mileni; Vsevolod Katritch; Gye Won Han; Eyal Vardy; Wei Liu; Aaron A Thompson; Xi-Ping Huang; F Ivy Carroll; S Wayne Mascarella; Richard B Westkaemper; Philip D Mosier; Bryan L Roth; Vadim Cherezov; Raymond C Stevens
Journal:  Nature       Date:  2012-03-21       Impact factor: 49.962

10.  Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic.

Authors:  Aaron A Thompson; Wei Liu; Eugene Chun; Vsevolod Katritch; Huixian Wu; Eyal Vardy; Xi-Ping Huang; Claudio Trapella; Remo Guerrini; Girolamo Calo; Bryan L Roth; Vadim Cherezov; Raymond C Stevens
Journal:  Nature       Date:  2012-05-16       Impact factor: 49.962
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  19 in total

1.  Chemotype-selective modes of action of κ-opioid receptor agonists.

Authors:  Eyal Vardy; Philip D Mosier; Kevin J Frankowski; Huixian Wu; Vsevolod Katritch; Richard B Westkaemper; Jeffrey Aubé; Raymond C Stevens; Bryan L Roth
Journal:  J Biol Chem       Date:  2013-10-11       Impact factor: 5.157

2.  The triplet puzzle theory indicates extensive formation of heteromers between opioid and chemokine receptor subtypes.

Authors:  Alexander O Tarakanov; Kjell Fuxe
Journal:  J Neural Transm (Vienna)       Date:  2015-07-02       Impact factor: 3.575

3.  Design, syntheses, and pharmacological characterization of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3'-carboxamido)morphinan analogues as opioid receptor ligands.

Authors:  Yunyun Yuan; Saheem A Zaidi; David L Stevens; Krista L Scoggins; Philip D Mosier; Glen E Kellogg; William L Dewey; Dana E Selley; Yan Zhang
Journal:  Bioorg Med Chem       Date:  2015-03-06       Impact factor: 3.641

4.  Computational insights into the subtype selectivity and "message-address-efficacy" mechanisms of opioid receptors through JDTic binding and unbinding.

Authors:  Jian-Xin Cheng; Tao Cheng; Wei-Hua Li; Gui-Xia Liu; Wei-Liang Zhu; Yun Tang
Journal:  Acta Pharmacol Sin       Date:  2017-10-19       Impact factor: 6.150

5.  Computational insights into the G-protein-biased activation and inactivation mechanisms of the μ opioid receptor.

Authors:  Jian-Xin Cheng; Tao Cheng; Wei-Hua Li; Gui-Xia Liu; Wei-Liang Zhu; Yun Tang
Journal:  Acta Pharmacol Sin       Date:  2017-11-30       Impact factor: 6.150

6.  A novel mechanism for cytoprotection against hypoxic injury: δ-opioid receptor-mediated increase in Nrf2 translocation.

Authors:  Shan Cao; Dongman Chao; Honghao Zhou; Gianfranco Balboni; Ying Xia
Journal:  Br J Pharmacol       Date:  2015-02-10       Impact factor: 8.739

Review 7.  Investigational peptide and peptidomimetic μ and δ opioid receptor agonists in the relief of pain.

Authors:  Aswini Kumar Giri; Victor J Hruby
Journal:  Expert Opin Investig Drugs       Date:  2013-12-13       Impact factor: 6.206

8.  Synthesis of ent-ketorfanol via a C-H alkenylation/torquoselective 6π electrocyclization cascade.

Authors:  Eric M Phillips; Tehetena Mesganaw; Ashay Patel; Simon Duttwyler; Brandon Q Mercado; Kendall N Houk; Jonathan A Ellman
Journal:  Angew Chem Int Ed Engl       Date:  2015-08-17       Impact factor: 15.336

9.  High- and low-affinity sites for sodium in δ-OR-Gi1α (Cys (351)-Ile (351)) fusion protein stably expressed in HEK293 cells; functional significance and correlation with biophysical state of plasma membrane.

Authors:  Miroslava Vošahlíková; Piotr Jurkiewicz; Lenka Roubalová; Martin Hof; Petr Svoboda
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2014-03-01       Impact factor: 3.000

10.  A Dynamic Picture of the Early Events in Nociceptin Binding to the NOP Receptor by Metadynamics.

Authors:  Stefano Della Longa; Alessandro Arcovito
Journal:  Biophys J       Date:  2016-09-20       Impact factor: 4.033
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