Literature DB >> 22589667

Interesting asian plants: their compounds and effects on electrophysiology and behaviour.

Jafri Malin Abdullah1.   

Abstract

There have been numerous non-scientific reports on the behavioural effects of Asian plants in humans who consumed these plants wholly or part thereof. Knowledge passed from generation to generation informs us of plants that increase effort and stamina, such as during paddy planting after the ingestion of Mitragyna speciosa Korth (ketum) as a tea supplement. Centella asiatica and Myristica fragrans are used as herbs to improve memory and to treat epilepsy, respectively. Zizyphus mauritiana is used to treat headache and burn pain, acts as an antitussive, and reduces rigor mortis immediately after death. These plants, which have been identified to exhibit analgaesic, muscle-relaxing, and nootropic effects, may contain important bio-compounds for medicinal chemistry and pharmaceutical research in Malaysia. The electrophysiology properties of these plants and their effects on epilepsy, behaviour, and pain will lead Malaysia to future new drug discoveries.

Entities:  

Keywords:  GABA; behaviour; electrophysiology; long-term potentiation; medicinal chemistry; neurosciences; plants

Year:  2011        PMID: 22589667      PMCID: PMC3328943     

Source DB:  PubMed          Journal:  Malays J Med Sci        ISSN: 1394-195X


  4 in total

1.  Effects of asiatic acid on passive and active avoidance task in male Spraque-Dawley rats.

Authors:  M N Nasir; M Habsah; I Zamzuri; G Rammes; J Hasnan; J Abdullah
Journal:  J Ethnopharmacol       Date:  2010-12-15       Impact factor: 4.360

2.  Evaluation of anxiolytic properties of Gotukola--(Centella asiatica) extracts and asiaticoside in rat behavioral models.

Authors:  P Wijeweera; J T Arnason; D Koszycki; Z Merali
Journal:  Phytomedicine       Date:  2006-02-20       Impact factor: 5.340

3.  Inhibitory effect of mitragynine, an analgesic alkaloid from Thai herbal medicine, on neurogenic contraction of the vas deferens.

Authors:  Kenjiro Matsumoto; Leonardo T Yamamoto; Kazuo Watanabe; Shingo Yano; Jie Shan; Peter K T Pang; Dhavadee Ponglux; Hiromitsu Takayama; Syunji Horie
Journal:  Life Sci       Date:  2005-08-16       Impact factor: 5.037

4.  Automated fast perfusion of Xenopus oocytes for drug screening.

Authors:  I Baburin; S Beyl; S Hering
Journal:  Pflugers Arch       Date:  2006-09-05       Impact factor: 3.657

  4 in total
  4 in total

1.  The Effect of 4-hydroxybenzaldehyde on the γ-aminobutyric Acid Type A Receptor.

Authors:  Jingli Zhang; Habsah Mohamad; Jia Hui Wong; Muhammad Bilal; Abdul Hadi Bin Ismail; Amelia Jane Lloyd; Abdul Aziz Mohamed Yusoff; Hasnah Osman; Kok Tong Wong; Zamzuri Idris; Jafri Malin Abdullah
Journal:  Malays J Med Sci       Date:  2017-04-14

2.  Effects of the Aqueous Extract of Anethum graveolens Leaves on Seizure Induced by Pentylenetetrazole in Mice.

Authors:  Akaberi Arash; Mohammad-Zadeh Mohammad; Mirmoosavi Seyed Jamal; Tazari Ali Mohammad; Abarashi Azam
Journal:  Malays J Med Sci       Date:  2013-10

3.  The Effects of 4-Hydroxybenzoic Acid Identified from Bamboo (Dendrocalamus asper) Shoots on Kv1.4 Channel.

Authors:  Jingli Zhang; Fatin H Mohamad; Jia Hui Wong; Habsah Mohamad; Abdul Hadi Ismail; Abdul Aziz Mohamed Yusoff; Hasnah Osman; Kok Tong Wong; Zamzuri Idris; Jafri Malin Abdullah
Journal:  Malays J Med Sci       Date:  2018-02-28

4.  Insights from zebrafish and mouse models on the activity and safety of ar-turmerone as a potential drug candidate for the treatment of epilepsy.

Authors:  Adriana Monserrath Orellana-Paucar; Tatiana Afrikanova; Joice Thomas; Yelaman K Aibuldinov; Wim Dehaen; Peter A M de Witte; Camila V Esguerra
Journal:  PLoS One       Date:  2013-12-13       Impact factor: 3.240

  4 in total

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