Literature DB >> 22583761

Assessing capacity for diagnosing tuberculosis in children in sub-Saharan African HIV care settings.

M J A Reid1, S Saito, R Fayorsey, R J Carter, E J Abrams.   

Abstract

Research on the prevalence of pediatric-specific tuberculosis (TB) diagnostics in sub-Saharan Africa is scarce. We assessed the availability of pediatric TB diagnostic tests at 651 pediatric human immunodeficiency virus care and treatment sites across nine African countries: 54% of the sites had access to sputum culture capacity and 51% to chest X-ray services. While 87% of sites had access to smear microscopy, only 6% had the capacity to perform sputum induction and 5% to perform gastric aspirate. These findings confirm that diagnostic resources for the accurate diagnosis of pediatric TB are limited. Capacity-building initiatives to improve sputum collection in children are urgently required.

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Year:  2012        PMID: 22583761      PMCID: PMC5920677          DOI: 10.5588/ijtld.11.0816

Source DB:  PubMed          Journal:  Int J Tuberc Lung Dis        ISSN: 1027-3719            Impact factor:   2.373


  6 in total

1.  Accuracy of the Xpert MTB/RIF test for the diagnosis of pulmonary tuberculosis in children admitted to hospital in Cape Town, South Africa: a descriptive study.

Authors:  Mark P Nicol; Lesley Workman; Washiefa Isaacs; Jacinta Munro; Faye Black; Brian Eley; Catharina C Boehme; Widaad Zemanay; Heather J Zar
Journal:  Lancet Infect Dis       Date:  2011-07-19       Impact factor: 25.071

2.  The pattern of tuberculosis in Queen Elizabeth Central Hospital, Blantyre, Malawi: 1986-1995.

Authors:  A D Harries; C Parry; L Nyongonya Mbewe; S M Graham; H M Daley; D Maher; F M Salaniponi; D S Nyangulu
Journal:  Int J Tuberc Lung Dis       Date:  1997-08       Impact factor: 2.373

3.  Induced sputum versus gastric lavage for microbiological confirmation of pulmonary tuberculosis in infants and young children: a prospective study.

Authors:  Heather J Zar; David Hanslo; Patricia Apolles; George Swingler; Gregory Hussey
Journal:  Lancet       Date:  2005 Jan 8-14       Impact factor: 79.321

Review 4.  A critical review of diagnostic approaches used in the diagnosis of childhood tuberculosis.

Authors:  A C Hesseling; H S Schaaf; R P Gie; J R Starke; N Beyers
Journal:  Int J Tuberc Lung Dis       Date:  2002-12       Impact factor: 2.373

Review 5.  Diagnostic and management challenges for childhood tuberculosis in the era of HIV.

Authors:  B J Marais; S M Graham; M F Cotton; N Beyers
Journal:  J Infect Dis       Date:  2007-08-15       Impact factor: 5.226

6.  Clinical presentation and outcome of tuberculosis in human immunodeficiency virus infected children on anti-retroviral therapy.

Authors:  Elisabetta Walters; Mark F Cotton; Helena Rabie; H Simon Schaaf; Lourens O Walters; Ben J Marais
Journal:  BMC Pediatr       Date:  2008-01-11       Impact factor: 2.125

  6 in total
  12 in total

Review 1.  Xpert MTB/RIF Ultra assay for tuberculosis disease and rifampicin resistance in children.

Authors:  Alexander W Kay; Tara Ness; Sabine E Verkuijl; Kerri Viney; Annemieke Brands; Tiziana Masini; Lucia González Fernández; Michael Eisenhut; Anne K Detjen; Anna M Mandalakas; Karen R Steingart; Yemisi Takwoingi
Journal:  Cochrane Database Syst Rev       Date:  2022-09-06

2.  Laboratory comparison of stool processing methods for Xpert® Ultra.

Authors:  C L Jasumback; Q Dlamini; J Kahari; G Maphalala; M G Dlamini; G S Dube; A DiNardo; H L Kirchner; A Mandalakas; A W Kay
Journal:  Public Health Action       Date:  2021-06-21

3.  Tuberculosis in Pediatric Antiretroviral Therapy Programs in Low- and Middle-Income Countries: Diagnosis and Screening Practices.

Authors:  Marie Ballif; Lorna Renner; Jean Claude Dusingize; Valeriane Leroy; Samuel Ayaya; Kara Wools-Kaloustian; Claudia P Cortes; Catherine C McGowan; Claire Graber; Anna M Mandalakas; Lynne M Mofenson; Matthias Egger; Ketut Dewi Kumara Wati; Revathy Nallusamy; Gary Reubenson; Mary-Ann Davies; Lukas Fenner
Journal:  J Pediatric Infect Dis Soc       Date:  2014-03-28       Impact factor: 3.164

4.  Stool Xpert MTB/RIF and urine lipoarabinomannan for the diagnosis of tuberculosis in hospitalized HIV-infected children.

Authors:  Sylvia M LaCourse; Patricia B Pavlinac; Lisa M Cranmer; Irene N Njuguna; Cyrus Mugo; John Gatimu; Joshua Stern; Judd L Walson; Elizabeth Maleche-Obimbo; Julius Oyugi; Dalton Wamalwa; Grace John-Stewart
Journal:  AIDS       Date:  2018-01-02       Impact factor: 4.177

5.  Feasibility of the string test for tuberculosis diagnosis in children between 4 and 14 years old.

Authors:  Karla T Tafur; Julia Coit; Segundo R Leon; Cynthia Pinedo; Silvia S Chiang; Carmen Contreras; Roger Calderon; Milagros J Mendoza; Leonid Lecca; Molly F Franke
Journal:  BMC Infect Dis       Date:  2018-11-15       Impact factor: 3.090

6.  Time-varying age- and CD4-stratified rates of mortality and WHO stage 3 and stage 4 events in children, adolescents and youth 0 to 24 years living with perinatally acquired HIV, before and after antiretroviral therapy initiation in the paediatric IeDEA Global Cohort Consortium.

Authors:  Sophie Desmonde; Anne M Neilan; Beverly Musick; Gabriela Patten; Kulkanya Chokephaibulkit; Andrew Edmonds; Stephany N Duda; Karen Malateste; Kara Wools-Kaloustian; Andrea L Ciaranello; Mary-Ann Davies; Valériane Leroy
Journal:  J Int AIDS Soc       Date:  2020-10       Impact factor: 5.396

7.  Variable Diagnostic Performance of Stool Xpert in Pediatric Tuberculosis: A Systematic Review and Meta-analysis.

Authors:  Meseret Gebre; Lindsay Hatzenbuehler Cameron; Getachew Tadesse; Yohannes Woldeamanuel; Liya Wassie
Journal:  Open Forum Infect Dis       Date:  2020-12-28       Impact factor: 3.835

8.  Xpert MTB/RIF and Xpert MTB/RIF Ultra assays for active tuberculosis and rifampicin resistance in children.

Authors:  Alexander W Kay; Lucia González Fernández; Yemisi Takwoingi; Michael Eisenhut; Anne K Detjen; Karen R Steingart; Anna M Mandalakas
Journal:  Cochrane Database Syst Rev       Date:  2020-08-27

9.  Tuberculosis among Children and Adolescents at HIV Treatment Centers in Sub-Saharan Africa.

Authors:  Anna M Mandalakas; Alexander W Kay; Jason M Bacha; Tara Devezin; Rachel Golin; Katherine R Simon; Dilsher Dhillon; Sandile Dlamini; Andrew DiNardo; Mogo Matshaba; Jill Sanders; Lineo Thahane; Pauline M Amuge; Saeed Ahmed; Moorine P Sekadde; Neway G Fida; Bhekumusa Lukhele; Nodumo Chidah; David Damba; Joseph Mhango; Moses Chodota; Makhorong Matsoso; Angelina Kayabu; Richard S Wanless; Gordon E Schutze
Journal:  Emerg Infect Dis       Date:  2020-12       Impact factor: 6.883

10.  Predictors of unsuccessful tuberculosis treatment outcomes in children from a prospective cohort study in Pakistan.

Authors:  Meredith B Brooks; Amyn Malik; Salman Khan; Junaid F Ahmed; Sara Siddiqui; Maria Jaswal; Saniya Saleem; Farhana Amanullah; Mercedes C Becerra; Hamidah Hussain
Journal:  J Glob Health       Date:  2021-02-11       Impact factor: 4.413

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