| Literature DB >> 22583648 |
Francine Novack Victoria1, Eder João Lenardão, Lucielli Savegnago, Gelson Perin, Raquel Guimarães Jacob, Diego Alves, Wladimir Padilha da Silva, Amanda de Souza da Motta, Patricia da Silva Nascente.
Abstract
Essential oil (EO) of the leaves of Eugenia uniflora L. (Brazilian cherry tree) was evaluated for its antioxidant, antibacterial and antifungal properties. The acute toxicity of the EO administered by oral route was also evaluated in mice. The EO exhibited antioxidant activity in the DPPH, ABTS and FRAP assays and reduced lipid peroxidation in the kidney of mice. The EO also showed antimicrobial activity against two important pathogenic bacteria, Staphylococcus aureus and Listeria monocytogenes, and against two fungi of the Candida species, C. lipolytica and C. guilliermondii. Acute administration of the EO by the oral route did not cause lethality or toxicological effects in mice. These findings suggest that the EO of the leaves of E. uniflora may have the potential for use in the pharmaceutical industry.Entities:
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Year: 2012 PMID： 22583648 DOI： 10.1016/j.fct.2012.05.002
Source DB: PubMed Journal: Food Chem Toxicol ISSN： 0278-6915 Impact factor: 6.023