Literature DB >> 22583604

A system for continual quality improvement of normal tissue delineation for radiation therapy treatment planning.

Jennifer Breunig1, Sophy Hernandez, Jeffrey Lin, Stacy Alsager, Christine Dumstorf, Jennifer Price, Jennifer Steber, Richard Garza, Suneel Nagda, Edward Melian, Bahman Emami, John C Roeske.   

Abstract

PURPOSE: To implement the "plan-do-check-act" (PDCA) cycle for the continual quality improvement of normal tissue contours used for radiation therapy treatment planning. METHODS AND MATERIALS: The CT scans of patients treated for tumors of the brain, head and neck, thorax, pancreas and prostate were selected for this study. For each scan, a radiation oncologist and a diagnostic radiologist, outlined the normal tissues ("gold" contours) using Radiation Therapy Oncology Group (RTOG) guidelines. A total of 30 organs were delineated. Independently, 5 board-certified dosimetrists and 1 trainee then outlined the same organs. Metrics used to compare the agreement between the dosimetrists' contours and the gold contours included the Dice Similarity Coefficient (DSC), and a penalty function using distance to agreement. Based on these scores, dosimetrists were re-trained on those organs in which they did not receive a passing score, and they were subsequently re-tested.
RESULTS: Passing scores were achieved on 19 of 30 organs evaluated. These scores were correlated to organ volume. For organ volumes <8 cc, the average DSC was 0.61 vs organ volumes ≥8 cc, for which the average DSC was 0.91 (P=.005). Normal tissues that had the lowest scores included the lenses, optic nerves, chiasm, cochlea, and esophagus. Of the 11 organs that were considered for re-testing, 10 showed improvement in the average score, and statistically significant improvement was noted in more than half of these organs after education and re-assessment.
CONCLUSIONS: The results of this study indicate the feasibility of applying the PDCA cycle to assess competence in the delineation of individual organs, and to identify areas for improvement. With testing, guidance, and re-evaluation, contouring consistency can be obtained across multiple dosimetrists. Our expectation is that continual quality improvement using the PDCA approach will ensure more accurate treatments and dose assessment in radiotherapy treatment planning and delivery.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID: 22583604     DOI: 10.1016/j.ijrobp.2012.02.003

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


  10 in total

1.  Simulation as More Than a Treatment-Planning Tool: A Systematic Review of the Literature on Radiation Oncology Simulation-Based Medical Education.

Authors:  Michael K Rooney; Fan Zhu; Erin F Gillespie; Jillian R Gunther; Ryan P McKillip; Matthew Lineberry; Ara Tekian; Daniel W Golden
Journal:  Int J Radiat Oncol Biol Phys       Date:  2018-06-06       Impact factor: 7.038

2.  Fully automatic multi-organ segmentation for head and neck cancer radiotherapy using shape representation model constrained fully convolutional neural networks.

Authors:  Nuo Tong; Shuiping Gou; Shuyuan Yang; Dan Ruan; Ke Sheng
Journal:  Med Phys       Date:  2018-09-19       Impact factor: 4.071

3.  Automatic multiorgan segmentation in thorax CT images using U-net-GAN.

Authors:  Xue Dong; Yang Lei; Tonghe Wang; Matthew Thomas; Leonardo Tang; Walter J Curran; Tian Liu; Xiaofeng Yang
Journal:  Med Phys       Date:  2019-03-22       Impact factor: 4.071

4.  Quantifying the dosimetric impact of organ-at-risk delineation variability in head and neck radiation therapy in the context of patient setup uncertainty.

Authors:  Eric Aliotta; Hamidreza Nourzadeh; Jeffrey Siebers
Journal:  Phys Med Biol       Date:  2019-07-05       Impact factor: 3.609

Review 5.  Esophageal cancer management controversies: Radiation oncology point of view.

Authors:  Patricia Tai; Edward Yu
Journal:  World J Gastrointest Oncol       Date:  2014-08-15

6.  Delineating brachial plexus, cochlea, pharyngeal constrictor muscles and optic chiasm in head and neck radiotherapy: a CT-based model atlas.

Authors:  Domenico Genovesi; Francesca Perrotti; Marianna Trignani; Angelo Di Pilla; Annamaria Vinciguerra; Antonietta Augurio; Monica Di Tommaso; Massimo Caulo; Massimo Savastano; Armando Tartaro; Antonio Raffaele Cotroneo; Giampiero Ausili Cèfaro
Journal:  Radiol Med       Date:  2014-08-05       Impact factor: 3.469

Review 7.  A review of deep learning based methods for medical image multi-organ segmentation.

Authors:  Yabo Fu; Yang Lei; Tonghe Wang; Walter J Curran; Tian Liu; Xiaofeng Yang
Journal:  Phys Med       Date:  2021-05-13       Impact factor: 2.685

8.  From prospective biobanking to precision medicine: BIO-RAIDs - an EU study protocol in cervical cancer.

Authors:  Charlotte Ngo; Sanne Samuels; Ksenia Bagrintseva; Andrea Slocker; Philippe Hupé; Gemma Kenter; Marina Popovic; Nina Samet; Patricia Tresca; Heiko von der Leyen; Eric Deutsch; Roman Rouzier; Lisa Belin; Maud Kamal; Suzy Scholl
Journal:  BMC Cancer       Date:  2015-11-04       Impact factor: 4.430

9.  Expertise Affects Inter-Observer Agreement at Peripheral Locations within a Brain Tumor.

Authors:  Emily M Crowe; William Alderson; Jonathan Rossiter; Christopher Kent
Journal:  Front Psychol       Date:  2017-09-20

10.  Contrast enhanced oesophageal avoidance for stereotactic body radiotherapy: Barium vs. Gastrografin.

Authors:  Katrina Woodford; Vanessa Panettieri; Jeremy D Ruben; Sidney Davis; Esther Sim; Trieumy Tran Le; Sashendra Senthi
Journal:  Tech Innov Patient Support Radiat Oncol       Date:  2019-12-16
  10 in total

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