Literature DB >> 22583390

Skin and subcutaneous thickness at injecting sites in children with diabetes: ultrasound findings and recommendations for giving injection.

Donatella Lo Presti1, Carmela Ingegnosi, Kenneth Strauss.   

Abstract

BACKGROUND: Children who inject insulin need clear guidelines as to the length of needle best for them. We studied the distance from surface to muscle in children in order to make needle choices which are evidence-based.
METHODS: One hundred one children with type 1 diabetes were divided into three groups according to age: 2-6, 7-13, and 14-17 yr. The thickness of skin and subcutaneous (SC) tissue was measured by ultrasound in all injection sites.
RESULTS: Skin thickness varied from 1.58 mm in the arm of the youngest children to 2.29 mm in the buttocks of the adolescents. Values decreased progressively based on age (2-6 < 7-13 < 14-17) and on body site (arm < thigh < abdomen < buttocks). Skin + SC thickness varied in a similar fashion. The skin surface to muscle distances were <4 mm in nearly 10% of children, especially in the 2-6 yr group. In this group, the rate of intramuscular (IM) injections using the 4-mm pen needle when a pinch-up is not used would be 20.2%. This rate of IM injections doubles when using the 5-mm needle, and when injections are given under similar conditions it triples using the 6-mm needle.
CONCLUSIONS: It seems medically appropriate for all children to use short needles where possible to minimize inadvertent IM injections which may increase glycemic variability. Currently, the safest needle for all children appears to be the 4-mm pen needle. However, when used in children aged 2-6 yr, it should be used with a pinched skin fold.
© 2012 John Wiley & Sons A/S.

Entities:  

Mesh:

Year:  2012        PMID: 22583390     DOI: 10.1111/j.1399-5448.2012.00865.x

Source DB:  PubMed          Journal:  Pediatr Diabetes        ISSN: 1399-543X            Impact factor:   4.866


  24 in total

1.  Randomized trial of infusion set function: steel versus teflon.

Authors:  Parul J Patel; Kari Benasi; Gina Ferrari; Mark G Evans; Satya Shanmugham; Darrell M Wilson; Bruce A Buckingham
Journal:  Diabetes Technol Ther       Date:  2013-10-03       Impact factor: 6.118

2.  Evaluating the Impact of Human Factors and Pen Needle Design on Insulin Pen Injection.

Authors:  Christopher Rini; Bruce C Roberts; Didier Morel; Rick Klug; Benjamin Selvage; Ronald J Pettis
Journal:  J Diabetes Sci Technol       Date:  2019-03-17

Review 3.  Diabetes in Childhood and Adolescence.

Authors:  Ralph Ziegler; Andreas Neu
Journal:  Dtsch Arztebl Int       Date:  2018-03-02       Impact factor: 5.594

4.  Paediatric type 1 diabetes 2018: Clinical and research insights.

Authors:  Stephen J Zborovski; Farid H Mahmud
Journal:  Paediatr Child Health       Date:  2018-03-28       Impact factor: 2.253

Review 5.  Forum for Injection Technique (FIT), India: The Indian recommendations 2.0, for best practice in Insulin Injection Technique, 2015.

Authors:  Nikhil Tandon; Sanjay Kalra; Yatan Pal Singh Balhara; Manash P Baruah; Manoj Chadha; Hemraj B Chandalia; Subhankar Chowdhury; Kesavadev Jothydev; Prasanna K M Kumar; Madhu S V; Ambrish Mithal; Sonal Modi; Shailesh Pitale; Rakesh Sahay; Rishi Shukla; Annamalai Sundaram; Ambika G Unnikrishnan; Subhash K Wangnoo
Journal:  Indian J Endocrinol Metab       Date:  2015 May-Jun

6.  The appropriateness of the length of insulin needles based on determination of skin and subcutaneous fat thickness in the abdomen and upper arm in patients with type 2 diabetes.

Authors:  Kang Hee Sim; Moon Sook Hwang; Sun Young Kim; Hye Mi Lee; Ji Yeun Chang; Moon Kyu Lee
Journal:  Diabetes Metab J       Date:  2014-04-18       Impact factor: 5.376

7.  A comparison study of patient ratings and safety of 32- and 34-gauge insulin pen needles.

Authors:  Satoru Yamada; Yoshifumi Yamada; Yoko Tsukamoto; Mitsuhisa Tabata; Junichiro Irie
Journal:  Diabetol Int       Date:  2015-10-28

8.  Forum for injection techniques, India: the first Indian recommendations for best practice in insulin injection technique.

Authors:  Sanjay Kalra; Yatan Pal Singh Balhara; Manash P Baruah; Manoj Chadha; Hemraj B Chandalia; Subhankar Chowdhury; K M Prasanna Kumar; Sonal Modi; Shailesh Pitale; Rishi Shukla; Rakesh Sahay; Annamalai Sundaram; Ambika G Unnikrishnan; Subhash K Wangnoo
Journal:  Indian J Endocrinol Metab       Date:  2012-11

9.  Poorer glycaemic control is associated with increased skin thickness at injection sites in children with type 1 diabetes.

Authors:  José G B Derraik; Marius Rademaker; Wayne S Cutfield; Jane M Peart; Craig Jefferies; Paul L Hofman
Journal:  Int J Pediatr Endocrinol       Date:  2014-02-27

10.  Effects of age, gender, BMI, and anatomical site on skin thickness in children and adults with diabetes.

Authors:  José G B Derraik; Marius Rademaker; Wayne S Cutfield; Teresa E Pinto; Sheryl Tregurtha; Ann Faherty; Jane M Peart; Paul L Drury; Paul L Hofman
Journal:  PLoS One       Date:  2014-01-21       Impact factor: 3.240

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.