Literature DB >> 2257903

Low threshold calcium spikes in medial vestibular nuclei neurones in vitro: a role in the generation of the vestibular nystagmus quick phase in vivo?

M Serafin1, A Khateb, C de Waele, P P Vidal, M Mühlethaler.   

Abstract

Intracellular recordings were obtained from medial vestibular nuclei neurones in guinea-pig brainstem slices. A subpopulation of neurones in this nucleus was found to have burst firing properties. Using ionic channel blockers the underlying mechanism was shown to be a low threshold calcium spike. It is speculated that this property could be implicated in the generation of the quick phase of the vestibular nystagmus in the behaving guinea-pig.

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Year:  1990        PMID: 2257903     DOI: 10.1007/bf00230850

Source DB:  PubMed          Journal:  Exp Brain Res        ISSN: 0014-4819            Impact factor:   1.972


  22 in total

1.  [The activity of single neurons in the region of vestibular nuclei in horizontal acceleration, with special reference to vestibular nystagmus].

Authors:  F DUENSING; K P SCHAEFER
Journal:  Arch Psychiatr Nervenkr Z Gesamte Neurol Psychiatr       Date:  1958

Review 2.  The intrinsic electrophysiological properties of mammalian neurons: insights into central nervous system function.

Authors:  R R Llinás
Journal:  Science       Date:  1988-12-23       Impact factor: 47.728

3.  Neuronal activity in the contralateral medial vestibular nucleus of the guinea pig following unilateral labyrinthectomy.

Authors:  P F Smith; I S Curthoys
Journal:  Brain Res       Date:  1988-03-22       Impact factor: 3.252

4.  Neuronal activity in the ipsilateral medial vestibular nucleus of the guinea pig following unilateral labyrinthectomy.

Authors:  P F Smith; I S Curthoys
Journal:  Brain Res       Date:  1988-03-22       Impact factor: 3.252

5.  Nature of synaptic events in cat abducens motoneurons at slow and quick phase of vestibular nystagmus.

Authors:  M Maeda; H Shimazu; Y Shinoda
Journal:  J Neurophysiol       Date:  1972-05       Impact factor: 2.714

6.  Excitatory premotor burst neurons in the cat pontine reticular formation related to the quick phase of vestibular nystagmus.

Authors:  Y Igusa; S Sasaki; H Shimazu
Journal:  Brain Res       Date:  1980-01-27       Impact factor: 3.252

7.  Reticulovestibular organization participating in generation of horizontal fast eye movement.

Authors:  S Sasaki; H Shimazu
Journal:  Ann N Y Acad Sci       Date:  1981       Impact factor: 5.691

8.  Functional organization of premotor neurons in the cat medial vestibular nucleus related to slow and fast phases of nystagmus.

Authors:  S Nakao; S Sasaki; R H Schor; H Shimazu
Journal:  Exp Brain Res       Date:  1982       Impact factor: 1.972

9.  Eye, head and body movements of the guinea pig in response to optokinetic stimulation and sinusoidal oscillation in yaw.

Authors:  M A Gresty
Journal:  Pflugers Arch       Date:  1975       Impact factor: 3.657

10.  Electrophysiology of guinea-pig cerebellar nuclear cells in the in vitro brain stem-cerebellar preparation.

Authors:  R Llinás; M Mühlethaler
Journal:  J Physiol       Date:  1988-10       Impact factor: 5.182

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  16 in total

1.  Intrinsic firing dynamics of vestibular nucleus neurons.

Authors:  Chris Sekirnjak; Sascha du Lac
Journal:  J Neurosci       Date:  2002-03-15       Impact factor: 6.167

2.  Medial vestibular nucleus in the guinea-pig. I. Intrinsic membrane properties in brainstem slices.

Authors:  M Serafin; C de Waele; A Khateb; P P Vidal; M Mühlethaler
Journal:  Exp Brain Res       Date:  1991       Impact factor: 1.972

Review 3.  Excitatory amino acid receptors in normal and abnormal vestibular function.

Authors:  P F Smith; C de Waele; P P Vidal; C L Darlington
Journal:  Mol Neurobiol       Date:  1991       Impact factor: 5.590

4.  Medial vestibular nucleus in the guinea-pig. II. Ionic basis of the intrinsic membrane properties in brainstem slices.

Authors:  M Serafin; C de Waele; A Khateb; P P Vidal; M Mühlethaler
Journal:  Exp Brain Res       Date:  1991       Impact factor: 1.972

Review 5.  Molecular mechanisms of brainstem plasticity. The vestibular compensation model.

Authors:  C L Darlington; H Flohr; P F Smith
Journal:  Mol Neurobiol       Date:  1991       Impact factor: 5.590

6.  Medial vestibular nucleus in the guinea-pig: histaminergic receptors. I. An in vitro study.

Authors:  M Serafin; A Khateb; N Vibert; P P Vidal; M Mühlethaler
Journal:  Exp Brain Res       Date:  1993       Impact factor: 1.972

7.  Medial vestibular nucleus in the guinea-pig: histaminergic receptors. II. An in vivo study.

Authors:  T Yabe; C de Waele; M Serafin; N Vibert; J M Arrang; M Mühlethaler; P P Vidal
Journal:  Exp Brain Res       Date:  1993       Impact factor: 1.972

8.  The horizontal vestibulo-ocular reflex in the hemilabyrinthectomized guinea-pig.

Authors:  N Vibert; C de Waele; M Escudero; P P Vidal
Journal:  Exp Brain Res       Date:  1993       Impact factor: 1.972

9.  Neuropharmacology of vestibular system disorders.

Authors:  Enrique Soto; Rosario Vega
Journal:  Curr Neuropharmacol       Date:  2010-03       Impact factor: 7.363

10.  Postsynaptic mechanisms underlying the excitatory action of histamine on medial vestibular nucleus neurons in rats.

Authors:  Xiao-Yang Zhang; Lei Yu; Qian-Xing Zhuang; Shi-Yu Peng; Jing-Ning Zhu; Jian-Jun Wang
Journal:  Br J Pharmacol       Date:  2013-09       Impact factor: 8.739

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