Literature DB >> 22575916

Manipulation and capture of Aβ amyloid fibrils and monomers by DC insulator gradient dielectrophoresis (DC-iGDEP).

Sarah J R Staton1, Paul V Jones, Ginger Ku, S Douglass Gilman, Indu Kheterpal, Mark A Hayes.   

Abstract

Here we report a novel method for the manipulation and concentration of Aβ amyloid fibrils, implicated in Alzheimer's disease, using DC insulating gradient dielectrophoresis (DC-iGDEP). Fibril enrichment was found to be ∼400%. Simulations suggest that capture of the full range of amyloid protein aggregates is possible with optimized device design.

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Year:  2012        PMID： 22575916     DOI： 10.1039/c2an35138b

Source DB:  PubMed          Journal:  Analyst        ISSN： 0003-2654            Impact factor:   4.616


  14 in total

1.  Differentiation of Escherichia coli serotypes using DC gradient insulator dielectrophoresis.

Authors:  Paul V Jones; Alexa F DeMichele; LaKeta Kemp; Mark A Hayes
Journal:  Anal Bioanal Chem       Date:  2013-11-08       Impact factor: 4.142

2.  Development of the resolution theory for gradient insulator-based dielectrophoresis.

Authors:  Paul V Jones; Mark A Hayes
Journal:  Electrophoresis       Date:  2015-05-05       Impact factor: 3.535

3.  Dielectrophoresis of proteins: experimental data and evolving theory.

Authors:  Mark A Hayes
Journal:  Anal Bioanal Chem       Date:  2020-04-21       Impact factor: 4.142

4.  Isolation and identification of Listeria monocytogenes utilizing DC insulator-based dielectrophoresis.

Authors:  Claire V Crowther; Shannon Huey Hilton; LaKeta Kemp; Mark A Hayes
Journal:  Anal Chim Acta       Date:  2019-03-12       Impact factor: 6.558

Review 5.  Protein dielectrophoresis and the link to dielectric properties.

Authors:  Fernanda Camacho-Alanis; Alexandra Ros
Journal:  Bioanalysis       Date:  2015       Impact factor: 2.681

6.  A mathematical model of dielectrophoretic data to connect measurements with cell properties.

Authors:  Shannon Huey Hilton; Mark A Hayes
Journal:  Anal Bioanal Chem       Date:  2019-03-16       Impact factor: 4.142

7.  Insulator-based dielectrophoresis with β-galactosidase in nanostructured devices.

Authors:  Asuka Nakano; Fernanda Camacho-Alanis; Alexandra Ros
Journal:  Analyst       Date:  2015-02-07       Impact factor: 4.616

8.  Refinement of insulator-based dielectrophoresis.

Authors:  Claire V Crowther; Mark A Hayes
Journal:  Analyst       Date:  2017-05-02       Impact factor: 4.616

Review 9.  Protein dielectrophoresis: advances, challenges, and applications.

Authors:  Asuka Nakano; Alexandra Ros
Journal:  Electrophoresis       Date:  2013-04       Impact factor: 3.535

10.  Biophysical separation of Staphylococcus epidermidis strains based on antibiotic resistance.

Authors:  Paul V Jones; Shannon Huey; Paige Davis; Ryan Yanashima; Ryan McLemore; Alex McLaren; Mark A Hayes
Journal:  Analyst       Date:  2015-08-07       Impact factor: 4.616
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