Literature DB >> 22575675

Out-of-field dose studies with an anthropomorphic phantom: comparison of X-rays and particle therapy treatments.

Chiara La Tessa1, Thomas Berger, Robert Kaderka, Dieter Schardt, Christine Körner, Ulla Ramm, Jörg Licher, Nakahiro Matsufuji, Christina Vallhagen Dahlgren, Tony Lomax, Günther Reitz, Marco Durante.   

Abstract

BACKGROUND AND
PURPOSE: Characterization of the out-of-field dose profile following irradiation of the target with a 3D treatment plan delivered with modern techniques.
METHODS: An anthropomorphic RANDO phantom was irradiated with a treatment plan designed for a simulated 5 × 2 × 5 cm(3) tumor volume located in the center of the head. The experiment was repeated with all most common radiation treatment types (photons, protons and carbon ions) and delivery techniques (Intensity Modulated Radiation Therapy, passive modulation and spot scanning). The measurements were performed with active diamond detector and passive thermoluminescence (TLD) detectors to investigate the out-of-field dose both inside and outside the phantom.
RESULTS: The highest out-of-field dose values both on the surface and inside the phantom were measured during the treatment with 25 MV photons. In the proximity of the Planned Target Volume (PTV), the lowest lateral dose profile was observed for passively modulated protons mainly because of the presence of the collimator in combination with the chosen volume shape. In the far out-of-field region (above 100mm from the PTV), passively modulated ions were characterized by a less pronounced dose fall-off in comparison with scanned beams. Overall, the treatment with scanned carbon ions delivered the lowest dose outside the target volume.
CONCLUSIONS: For the selected PTV, the use of the collimator in proton therapy drastically reduced the dose deposited by ions or photons nearby the tumor. Scanning modulation represents the optimal technique for achieving the highest dose reduction far-out-of-field.
Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

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Year:  2012        PMID: 22575675     DOI: 10.1016/j.radonc.2012.04.004

Source DB:  PubMed          Journal:  Radiother Oncol        ISSN: 0167-8140            Impact factor:   6.280


  6 in total

1.  EURADOS strategic research agenda: vision for dosimetry of ionising radiation.

Authors:  W Rühm; E Fantuzzi; R Harrison; H Schuhmacher; F Vanhavere; J Alves; J F Bottollier Depois; P Fattibene; Ž Knežević; M A Lopez; S Mayer; S Miljanić; S Neumaier; P Olko; H Stadtmann; R Tanner; C Woda
Journal:  Radiat Prot Dosimetry       Date:  2015-03-09       Impact factor: 0.972

2.  Measurement and modeling of out-of-field doses from various advanced post-mastectomy radiotherapy techniques.

Authors:  Jihyung Yoon; David Heins; Xiaodong Zhao; Mary Sanders; Rui Zhang
Journal:  Phys Med Biol       Date:  2017-11-13       Impact factor: 3.609

Review 3.  Charged particle therapy--optimization, challenges and future directions.

Authors:  Jay S Loeffler; Marco Durante
Journal:  Nat Rev Clin Oncol       Date:  2013-05-21       Impact factor: 66.675

4.  New Ions for Therapy.

Authors:  Francesco Tommasino; Emanuele Scifoni; Marco Durante
Journal:  Int J Part Ther       Date:  2016-02-09

5.  Modelling and measurements of distributions in an adult human phantom undergoing proton scanning beam radiotherapy: lung- and prostate-located tumours.

Authors:  Monika Puchalska
Journal:  Radiat Environ Biophys       Date:  2021-03-02       Impact factor: 1.925

6.  Peripheral dose measurements with diode and thermoluminescence dosimeters for intensity modulated radiotherapy delivered with conventional and un-conventional linear accelerator.

Authors:  Rajesh Kinhikar; Poonam Gamre; Chandrashekhar Tambe; Sudarshan Kadam; George Biju; C S Magai; Dipak Dhote; Shyam Shrivastava; Deepak Deshpande
Journal:  J Med Phys       Date:  2013-01
  6 in total

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