Literature DB >> 22575446

ATP-citrate lyase: a mini-review.

Melanie Chypre1, Nousheen Zaidi, Karine Smans.   

Abstract

ATP-citrate lyase (ACLY) is a cytosolic enzyme that catalyzes generation of acetyl-CoA from citrate. Acetyl-CoA is a vital building block for the endogenous biosynthesis of fatty acids and cholesterol and is involved in isoprenoid-based protein modifications. Acetyl-CoA is also required for acetylation reactions that modify proteins such as histone acetylation. In the present review some of the known features of ACLY such as tissue distribution, subcellular localization, enzymatic properties, gene regulation and associated physiological conditions are highlighted.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID： 22575446     DOI： 10.1016/j.bbrc.2012.04.144

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  66 in total

1.  Polymorphisms, de novo lipogenesis, and plasma triglyceride response following fish oil supplementation.

Authors:  Annie Bouchard-Mercier; Iwona Rudkowska; Simone Lemieux; Patrick Couture; Marie-Claude Vohl
Journal:  J Lipid Res       Date:  2013-07-25       Impact factor: 5.922

2.  microRNA profiling: increased expression of miR-147a and miR-518e in progressive supranuclear palsy (PSP).

Authors:  Roman Tatura; Malte Buchholz; Dennis W Dickson; John van Swieten; Catriona McLean; Günter Höglinger; Ulrich Müller
Journal:  Neurogenetics       Date:  2016-04-06       Impact factor: 2.660

3.  Physiological characterization of ATP-citrate lyase in Aspergillus niger.

Authors:  Hong Chen; Xihong He; Hongran Geng; Hao Liu
Journal:  J Ind Microbiol Biotechnol       Date:  2014-02-25       Impact factor: 3.346

Review 4.  The vital role of ATP citrate lyase in chronic diseases.

Authors:  Amrita Devi Khwairakpam; Kishore Banik; Sosmitha Girisa; Bano Shabnam; Mehdi Shakibaei; Lu Fan; Frank Arfuso; Javadi Monisha; Hong Wang; Xinliang Mao; Gautam Sethi; Ajaikumar B Kunnumakkara
Journal:  J Mol Med (Berl)       Date:  2019-12-19       Impact factor: 4.599

5.  An allosteric mechanism for potent inhibition of human ATP-citrate lyase.

Authors:  Jia Wei; Silvana Leit; Jun Kuai; Eric Therrien; Salma Rafi; H James Harwood; Byron DeLaBarre; Liang Tong
Journal:  Nature       Date:  2019-04-03       Impact factor: 49.962

6.  Genome-wide identification of citrus ATP-citrate lyase genes and their transcript analysis in fruits reveals their possible role in citrate utilization.

Authors:  Xiao-Mei Hu; Cai-Yun Shi; Xiao Liu; Long-Fei Jin; Yong-Zhong Liu; Shu-Ang Peng
Journal:  Mol Genet Genomics       Date:  2014-08-13       Impact factor: 3.291

7.  Regulation of protein metabolism in cancer.

Authors:  Cecil Han; Xiongbin Lu; Deepak Nagrath
Journal:  Mol Cell Oncol       Date:  2018-05-10

8.  Cyclin E Associates with the Lipogenic Enzyme ATP-Citrate Lyase to Enable Malignant Growth of Breast Cancer Cells.

Authors:  Kimberly S Lucenay; Iman Doostan; Cansu Karakas; Tuyen Bui; Zhiyong Ding; Gordon B Mills; Kelly K Hunt; Khandan Keyomarsi
Journal:  Cancer Res       Date:  2016-02-29       Impact factor: 12.701

9.  Diacylglycerol kinase delta promotes lipogenesis.

Authors:  Yulia V Shulga; Dessi Loukov; Pavlina T Ivanova; Stephen B Milne; David S Myers; Grant M Hatch; G Umeh; Divyanshi Jalan; Morgan D Fullerton; Gregory R Steinberg; Matthew K Topham; H Alex Brown; Richard M Epand
Journal:  Biochemistry       Date:  2013-10-23       Impact factor: 3.162

10.  Glucose-dependent de novo lipogenesis in B lymphocytes: a requirement for atp-citrate lyase in lipopolysaccharide-induced differentiation.

Authors:  Fay J Dufort; Maria R Gumina; Nathan L Ta; Yongzhen Tao; Shannon A Heyse; David A Scott; Adam D Richardson; Thomas N Seyfried; Thomas C Chiles
Journal:  J Biol Chem       Date:  2014-01-27       Impact factor: 5.157
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