Literature DB >> 22567208

Epidemiological characteristics of corneal ulcers in South sharqiya region.

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Abstract

OBJECTIVES: To understand the epidemiology, predisposing factors, etiology and the outcome of management of corneal ulcers in South Sharqiya Region of Oman.
METHODS: 188 patients who presented to us in eye Ophthalmology Department of Sur regional hospital with corneal ulcers were analyzed retrospectively. The historical aspects including the systemic and local predisposing factors, clinical picture of the ulcer which was noted on slit lamp at the time of presentation, results of culture for which material was taken by scraping of the ulcer, and its sensitivity pattern, type of management, and its outcome, were noted and the results were interpreted.
RESULTS: 60.83% were males above the age of 60 years. Severe ulcers were seen in 36.17% of cases. 43.18% of cases showed positive culture of which 88.2% were bacteria and rest were fungal isolates. Of the bacteria 53.84% were pseudomonas, and 20% staphylococcus. 83.5% were put on fortified gentamycin and 68.61% were on cefuroxime in the initial dual therapy. 37.23% were on ciprofloxacin one time or another during the course of the ulcer. 69.14% of cases recovered fully and 9.57% improved. 54.25% needed hospitalization for less than 1 week and 34% for less than 2 weeks. 58.76% of cases recovered in less than 3 weeks. As local predisposing factors 45 cases (24%) were post surgery, and 29 cases (15.4%) were having CDK (climatic droplet keratopathy). Diabetes was seen in 8.5% of cases.
CONCLUSION: Corneal ulcer was seen predominantly in males above the age of 60 years, pseudomonas being the main etiological organism. Dual therapy was the commonest empirical therapy. No major systemic risk factor was identified. Post surgical and CDK were the predominant local risk factors.

Entities:  

Keywords:  corneal ulcer; dual therapy; pseudomonas

Year:  2008        PMID: 22567208      PMCID: PMC3338994     

Source DB:  PubMed          Journal:  Oman Med J        ISSN: 1999-768X


  12 in total

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2.  Microbial keratitis predisposing factors and morbidity.

Authors:  Lisa Keay; Katie Edwards; Thomas Naduvilath; Hugh R Taylor; Grant R Snibson; Kevin Forde; Fiona Stapleton
Journal:  Ophthalmology       Date:  2005-12-19       Impact factor: 12.079

3.  Ofloxacin monotherapy for the primary treatment of microbial keratitis: a double-masked, randomized, controlled trial with conventional dual therapy. The Ofloxacin Study Group.

Authors: 
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4.  Aetiology of suppurative corneal ulcers in Ghana and south India, and epidemiology of fungal keratitis.

Authors:  A K Leck; P A Thomas; M Hagan; J Kaliamurthy; E Ackuaku; M John; M J Newman; F S Codjoe; J A Opintan; C M Kalavathy; V Essuman; C A N Jesudasan; G J Johnson
Journal:  Br J Ophthalmol       Date:  2002-11       Impact factor: 4.638

5.  Epidemiological and microbiological diagnosis of suppurative keratitis in Gangetic West Bengal, eastern India.

Authors:  Samar K Basak; Sukumar Basak; Ayan Mohanta; Arup Bhowmick
Journal:  Indian J Ophthalmol       Date:  2005-03       Impact factor: 1.848

6.  Epidemiology and aetiological diagnosis of corneal ulceration in Madurai, south India.

Authors:  M Srinivasan; C A Gonzales; C George; V Cevallos; J M Mascarenhas; B Asokan; J Wilkins; G Smolin; J P Whitcher
Journal:  Br J Ophthalmol       Date:  1997-11       Impact factor: 4.638

7.  The role of smears, cultures, and antibiotic sensitivity testing in the management of suspected infectious keratitis.

Authors:  S D McLeod; A Kolahdouz-Isfahani; K Rostamian; C W Flowers; P P Lee; P J McDonnell
Journal:  Ophthalmology       Date:  1996-01       Impact factor: 12.079

8.  Epidemiological characteristics of microbiological results on patients with infectious corneal ulcers: a 13-year survey in Paraguay.

Authors:  Florentina Laspina; Margarita Samudio; Diógenes Cibils; Christopher N Ta; Norma Fariña; Ramona Sanabria; Volker Klauss; Herminia Miño de Kaspar
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2004-02-04       Impact factor: 3.117

9.  Epidemiologic characteristics, predisposing factors, and etiologic diagnosis of corneal ulceration in Nepal.

Authors:  M P Upadhyay; P C Karmacharya; S Koirala; N R Tuladhar; L E Bryan; G Smolin; J P Whitcher
Journal:  Am J Ophthalmol       Date:  1991-01-15       Impact factor: 5.258

10.  Decision-making in the management of microbial keratitis.

Authors:  D B Jones
Journal:  Ophthalmology       Date:  1981-08       Impact factor: 12.079

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  5 in total

1.  Microbiological profile of corneal ulcer cases diagnosed in a tertiary care ophthalmological institute in Nepal.

Authors:  Sharmila Suwal; Dinesh Bhandari; Pratigya Thapa; Mohan Krishna Shrestha; Jyoti Amatya
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2.  The epidemiology of nonviral microbial keratitis in a tertiary care center in Muscat, Oman.

Authors:  Alyaqdhan Al-Ghafri; Abdullatif Al-Raisi
Journal:  Oman J Ophthalmol       Date:  2018 Sep-Dec

Review 3.  Mycotic Keratitis-A Global Threat from the Filamentous Fungi.

Authors:  Jeremy J Hoffman; Matthew J Burton; Astrid Leck
Journal:  J Fungi (Basel)       Date:  2021-04-03

4.  Microbiological Profiles of Ocular Fungal Infection at an Ophthalmic Referral Hospital in Southern China: A Ten-Year Retrospective Study.

Authors:  Yinhui Pei; Xiaoling Chen; Yiwei Tan; Xiuping Liu; Fang Duan; Kaili Wu
Journal:  Infect Drug Resist       Date:  2022-06-22       Impact factor: 4.177

5.  Management of infective corneal ulcers in a high-income developing country.

Authors:  Tahra AlMahmoud; Mohamed Elhanan; Mohamed H Elshamsy; Hanan N Alshamsi; Fikri M Abu-Zidan
Journal:  Medicine (Baltimore)       Date:  2019-12       Impact factor: 1.889

  5 in total

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