BACKGROUND: It is controversial whether cerebral deficits other than frank stroke develop after total aortic arch replacement using hypothermic circulatory arrest (HCA) with antegrade selective cerebral perfusion (SCP). OBJECTIVES: We investigated neuropsychological functions in patients who received total aortic arch replacement using deep HCA with SCP. METHODS: Eleven patients who underwent elective total arch replacement using deep HCA with antegrade SCP were included. Cognitive functions of the patients were evaluated at baseline, and 3 weeks and 6 months after the aortic arch surgery. RESULTS: The performance of cognitive tests did not change 3 weeks after surgery, except for the attention/calculation task of the Mini-Mental State Examination (MMSE). Six months after surgery, the decline in score for the attention/calculation task in the MMSE had reversed and the score for this task as well as for all other tests had returned to baseline levels. CONCLUSION: Long-lasting cognitive deficits other than frank stroke may not develop after total arch replacement surgery using deep HCA with SCP.
BACKGROUND: It is controversial whether cerebral deficits other than frank stroke develop after total aortic arch replacement using hypothermic circulatory arrest (HCA) with antegrade selective cerebral perfusion (SCP). OBJECTIVES: We investigated neuropsychological functions in patients who received total aortic arch replacement using deep HCA with SCP. METHODS: Eleven patients who underwent elective total arch replacement using deep HCA with antegrade SCP were included. Cognitive functions of the patients were evaluated at baseline, and 3 weeks and 6 months after the aortic arch surgery. RESULTS: The performance of cognitive tests did not change 3 weeks after surgery, except for the attention/calculation task of the Mini-Mental State Examination (MMSE). Six months after surgery, the decline in score for the attention/calculation task in the MMSE had reversed and the score for this task as well as for all other tests had returned to baseline levels. CONCLUSION: Long-lasting cognitive deficits other than frank stroke may not develop after total arch replacement surgery using deep HCA with SCP.
Authors: D L Reich; S Uysal; M Sliwinski; M A Ergin; R A Kahn; S N Konstadt; J McCullough; M R Hibbard; W A Gordon; R B Griepp Journal: J Thorac Cardiovasc Surg Date: 1999-01 Impact factor: 5.209
Authors: L G Svensson; E M Nadolny; D L Penney; J Jacobson; W A Kimmel; M H Entrup; R S D'Agostino Journal: Ann Thorac Surg Date: 2001-06 Impact factor: 4.330