OBJECTIVE: To investigate the degree of calcification of fresh autologous pericardium applied for posterior mitral annuloplasty and its influence on the repaired mitral valve. METHODS: Thirty-nine patients (31 degenerative and 8 infective endocarditis; mean age at surgery: 62 ± 11 years) were enrolled in this study. Sixteen-slice multi-detector computed tomography was performed to identify calcification of autologous pericardium. The mean clinical follow-up was 4.6 ± 2.6 years (maximum 8.8 years) and the mean computed tomography follow-up period was 3.6 ± 2.5 years (maximum 7.6 years) after surgery. RESULTS: Pericardial calcification was detected in 15 patients. The earliest detection of calcification was 2.5 years after surgery. There was a weak correlation between pericardial calcification and postoperative years (Pearson's product correlation coefficient: 0.476; p = 0.0019). However, severe calcification of autologous pericardium did not occur in any case. There was no association between pericardial calcification and recurrent mitral regurgitation (p = 0.1145). The mean mitral valve orifice area and the mean transmitral pressure gradient in the 15 patients with calcification were 3.0 ± 0.6 cm(2) and 2.1 ± 1.0 mmHg, respectively. CONCLUSIONS: Calcification of the fresh autologous pericardium increased with postoperative years. It had no adverse effects on repaired mitral valve in the short-term follow-up period. We will report the findings once again when the follow-up reaches 10 years.
OBJECTIVE: To investigate the degree of calcification of fresh autologous pericardium applied for posterior mitral annuloplasty and its influence on the repaired mitral valve. METHODS: Thirty-nine patients (31 degenerative and 8 infective endocarditis; mean age at surgery: 62 ± 11 years) were enrolled in this study. Sixteen-slice multi-detector computed tomography was performed to identify calcification of autologous pericardium. The mean clinical follow-up was 4.6 ± 2.6 years (maximum 8.8 years) and the mean computed tomography follow-up period was 3.6 ± 2.5 years (maximum 7.6 years) after surgery. RESULTS:Pericardial calcification was detected in 15 patients. The earliest detection of calcification was 2.5 years after surgery. There was a weak correlation between pericardial calcification and postoperative years (Pearson's product correlation coefficient: 0.476; p = 0.0019). However, severe calcification of autologous pericardium did not occur in any case. There was no association between pericardial calcification and recurrent mitral regurgitation (p = 0.1145). The mean mitral valve orifice area and the mean transmitral pressure gradient in the 15 patients with calcification were 3.0 ± 0.6 cm(2) and 2.1 ± 1.0 mmHg, respectively. CONCLUSIONS:Calcification of the fresh autologous pericardium increased with postoperative years. It had no adverse effects on repaired mitral valve in the short-term follow-up period. We will report the findings once again when the follow-up reaches 10 years.
Authors: E Braunberger; A Deloche; A Berrebi; F Abdallah; J A Celestin; P Meimoun; G Chatellier; S Chauvaud; J N Fabiani; A Carpentier Journal: Circulation Date: 2001-09-18 Impact factor: 29.690
Authors: A M Gillinov; D M Cosgrove; B W Lytle; P C Taylor; R W Stewart; P M McCarthy; N G Smedira; D D Muehrcke; C Apperson-Hansen; F D Loop Journal: J Thorac Cardiovasc Surg Date: 1997-03 Impact factor: 5.209
Authors: S Chauvaud; V Jebara; J C Chachques; B el Asmar; S Mihaileanu; P Perier; G Dreyfus; J Relland; J P Couetil; A Carpentier Journal: J Thorac Cardiovasc Surg Date: 1991-08 Impact factor: 5.209
Authors: A Marc Gillinov; Kriangkrai Tantiwongkosri; Eugene H Blackstone; Penny L Houghtaling; Edward R Nowicki; Joseph F Sabik; Douglas R Johnston; Lars G Svensson; Tomislav Mihaljevic Journal: Ann Thorac Surg Date: 2009-07 Impact factor: 4.330