Literature DB >> 22553676

Application of ultrasound contrast in identification and diagnosis of ocular spaceoccupying lesions.

Jia-Ying Yuan1, Jian-Hua Zhang, Chong Tang, Jing-Zhi Zhao, Chao Pang, Xin-Chun Ren, Hong Zhu, Yun-Tao Zhang.   

Abstract

AIM: To analyze the application significance of ultrasound contrast agent in identification and diagnosis of ocular spaceoccupying lesions, and mainly analyze its advantages and problems.
METHODS: Thirty-two representative literatures about the application of ultrasound contrast agent in diagnosis of spaceoccupying lesions at home and abroad were collected after focused on sorting the literature reporting the application of ultrasound contrast diagnostic technology in the diagnosis and identification of ocular spaceoccupying lesions in recent years. Its advantages and problems were retrospectively analyzed, and reasonable assessment on existing problems was made and possible solutions to the problems were proposed.
RESULTS: As a new imaging diagnostic technique, the contrast-enhanced ultrasound, which can enhance the display of tumor microcirculation vessels and improve the tumor's ultrasound diagnostic capability, was analyzed. Through sorting and comprehensively analyzing the collected literatures, the positive rate of ocular spaceoccupying lesion diagnosis could be significantly improved with ultrasound contrast technology. Thus, the vascular perfusion in normal tissues and lesions was reflected objectively. According to the lesion's perfusion characteristics of the contrast agent plus with the performance features of two-dimensional ultrasound, the ocular spaceoccupying lesions can be accurately diagnosed, and this could provide clinicians with reliable research basis in this field.
CONCLUSION: Ultrasound contrast examination is a new testing method, and ultrasound contrast agent can significantly enhance the ultrasonic detection signal, clearly show the blood perfusion in vessels and tissues, increase the image contrast resolution, and improve the lesion's detection capability in the microcirculation perfusion level, especially its important value in the diagnosis of ocular tumor.

Entities:  

Keywords:  differential diagnosis; new microbubble contrast agent; ocular spaceoccupying lesion; ultrasound contrast

Year:  2011        PMID: 22553676      PMCID: PMC3340855          DOI: 10.3980/j.issn.2222-3959.2011.04.02

Source DB:  PubMed          Journal:  Int J Ophthalmol        ISSN: 2222-3959            Impact factor:   1.779


  9 in total

1.  Echoscintigraphy: a new imaging modality for the reduction of color blooming and acoustic shadowing in contrast sonography.

Authors:  Thomas Schlosser; Christoph Pohl; Stefanie Kuntz-Hehner; Heyder Omran; Harald Becher; Klaus Tiemann
Journal:  Ultrasound Med Biol       Date:  2003-07       Impact factor: 2.998

2.  Human pharmacokinetics and safety evaluation of SonoVue, a new contrast agent for ultrasound imaging.

Authors:  D R Morel; I Schwieger; L Hohn; J Terrettaz; J B Llull; Y A Cornioley; M Schneider
Journal:  Invest Radiol       Date:  2000-01       Impact factor: 6.016

3.  High-frequency contrast harmonic imaging of ophthalmic tumor perfusion.

Authors:  Klaus Schlottmann; Barbara Fuchs-Koelwel; Martina Demmler-Hackenberg; Veit-Peter Gabel; Jürgen Schölmerich
Journal:  AJR Am J Roentgenol       Date:  2005-02       Impact factor: 3.959

4.  Contrast-enhanced color Doppler sonography of uveal melanomas.

Authors:  A J Lemke; N Hosten; M Richter; N E Bechrakis; P Foerster; R Puls; M Gutberlet; R Felix
Journal:  J Clin Ultrasound       Date:  2001-05       Impact factor: 0.910

5.  [Doppler color ultrasonography with contrast media in the study of eye and orbit neoplasms].

Authors:  V Coppola; G Vallone; D Verrengia; M Alfinito; V Molese; L Brunese; F Smaltino
Journal:  Radiol Med       Date:  1997-04       Impact factor: 3.469

6.  Clinical safety of SonoVue, a new contrast agent for ultrasound imaging, in healthy volunteers and in patients with chronic obstructive pulmonary disease.

Authors:  D Bokor; J B Chambers; P J Rees; T G Mant; F Luzzani; A Spinazzi
Journal:  Invest Radiol       Date:  2001-02       Impact factor: 6.016

7.  Multi-centre clinical study evaluating the efficacy of SonoVue (BR1), a new ultrasound contrast agent in Doppler investigation of focal hepatic lesions.

Authors:  E Leen; W J Angerson; S Yarmenitis; G Bongartz; M Blomley; A Del Maschio; V Summaria; G Maresca; C Pezzoli; J B Llull
Journal:  Eur J Radiol       Date:  2002-03       Impact factor: 3.528

8.  Echographic examination with new generation contrast agent of choroidal malignant melanomas.

Authors:  R Forte; G Cennamo; S Staibano; G De Rosa
Journal:  Acta Ophthalmol Scand       Date:  2005-06

9.  Significance of angiogenesis and microvascular invasion in renal cell carcinoma.

Authors:  Yoram Dekel; Rumelia Koren; Valentina Kugel; Pinhas M Livne; Rivka Gal
Journal:  Pathol Oncol Res       Date:  2002       Impact factor: 3.201

  9 in total

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