OBJECTIVES/HYPOTHESIS: The first International Union Against Cancer (UICC) TNM classification for aerodigestive malignant mucosal melanoma was not published until 2009, and since then, only a few studies have evaluated the accuracy of this staging system. Our aim was to evaluate the accuracy of this UICC staging system for sinonasal malignant mucosal melanoma (SMMM) in a nationwide survey. STUDY DESIGN: Retrospective, population-based, multicenter study. METHODS: The hospital surgical and discharge registries were used to identify the patients. A database including demographic and clinicopathologic variable was created. RESULTS: Altogether, 50 SMMM patients diagnosed in Finland from 1990 to 2004 were evaluated. Three- and 5-year overall survival rates were 44% and 27%, respectively. Significant differences in overall survival according to T classification (P = .028, log rank) and stage (P = .02, log rank) were found. Tumor extension to the sphenoid sinus had a significant negative impact on survival (n = 11, P = .03, log rank). CONCLUSIONS: The current UICC staging system for mucosal melanoma provides a useful format for staging SMMMs in clinical settings.
OBJECTIVES/HYPOTHESIS: The first International Union Against Cancer (UICC) TNM classification for aerodigestive malignant mucosal melanoma was not published until 2009, and since then, only a few studies have evaluated the accuracy of this staging system. Our aim was to evaluate the accuracy of this UICC staging system for sinonasal malignant mucosal melanoma (SMMM) in a nationwide survey. STUDY DESIGN: Retrospective, population-based, multicenter study. METHODS: The hospital surgical and discharge registries were used to identify the patients. A database including demographic and clinicopathologic variable was created. RESULTS: Altogether, 50 SMMM patients diagnosed in Finland from 1990 to 2004 were evaluated. Three- and 5-year overall survival rates were 44% and 27%, respectively. Significant differences in overall survival according to T classification (P = .028, log rank) and stage (P = .02, log rank) were found. Tumor extension to the sphenoid sinus had a significant negative impact on survival (n = 11, P = .03, log rank). CONCLUSIONS: The current UICC staging system for mucosal melanoma provides a useful format for staging SMMMs in clinical settings.
Authors: Stephanie Flukes; Shivangi Lohia; Christopher A Barker; Jennifer R Cracchiolo; Ian Ganly; Snehal G Patel; Benjamin R Roman; Jatin P Shah; Alexander N Shoushtari; Viviane Tabar; Akash Shah; Marc A Cohen Journal: Head Neck Date: 2020-08-01 Impact factor: 3.147
Authors: O Stanimirov Rossi; Domenic Vital; M B Soyka; T N Roth; G F Huber; D Holzmann Journal: Eur Arch Otorhinolaryngol Date: 2014-05-29 Impact factor: 2.503
Authors: Fernando López; Juan P Rodrigo; Antonio Cardesa; Asterios Triantafyllou; Kenneth O Devaney; William M Mendenhall; Missak Haigentz; Primož Strojan; Phillip K Pellitteri; Carol R Bradford; Ashok R Shaha; Jennifer L Hunt; Remco de Bree; Robert P Takes; Alessandra Rinaldo; Alfio Ferlito Journal: Head Neck Date: 2015-05-22 Impact factor: 3.147
Authors: Robert M Samstein; Richard D Carvajal; Michael A Postow; Margaret K Callahan; Alexander N Shoushtari; Snehal G Patel; Nancy Y Lee; Christopher A Barker Journal: Head Neck Date: 2016-04-04 Impact factor: 3.147
Authors: K Luna-Ortiz; M Aguilar-Romero; V Villavicencio-Valencia; E Zepeda-Castilla; H Vidrio-Morgado; N Peteuil; A Mosqueda-Taylor Journal: Med Oral Patol Oral Cir Bucal Date: 2016-07-01
Authors: Anna Hafström; Eva Brun; Simon Persson; Johanna Sjövall; Peter Wahlberg; Lennart Greiff Journal: Laryngoscope Investig Otolaryngol Date: 2019-11-22