Literature DB >> 24871862

Multilocular sinonasal malignant melanoma: a poor prognostic subgroup?

O Stanimirov Rossi1, Domenic Vital, M B Soyka, T N Roth, G F Huber, D Holzmann.   

Abstract

Clinical observations show that two subtypes of sinonasal malignant melanoma exist: uni- and multilocular melanoma. The aim of this retrospective study was to determine the prevalence and outcome of multilocular sinonasal malignant melanoma. All patients with sinonasal malignant melanoma treated at our institution between 1992 and 2011 were included. Survival and recurrence data were analyzed related to the distribution pattern of the tumors and other factors. Twenty-five patients were identified and included in the analysis. Seven patients (28 %) suffered from multilocular, the remaining 18 patients (72 %) from unilocular sinonasal malignant melanoma. The first group showed a significantly worse disease-free survival, whereas disease-specific and overall survival did not differ between the two subtypes. Multilocular sinonasal malignant melanoma is associated with an unfavorable disease-free survival compared to its unilocular counterpart.

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Mesh：

Year:  2014        PMID： 24871862     DOI： 10.1007/s00405-014-3098-z

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN： 0937-4477            Impact factor:   2.503


  31 in total

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4.  Clinicopathologic differences in malignant melanoma arising in oral squamous and sinonasal respiratory mucosa of the upper aerodigestive tract.

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5.  The role of postoperative adjuvant radiation therapy in the treatment of mucosal melanomas of the head and neck region.

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Journal:  Arch Otolaryngol Head Neck Surg       Date:  2003-08

6.  Sinonasal melanoma: a clinicopathologic review of 61 cases.

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7.  Primary mucosal melanoma of the head and neck. Comparison of clinical presentation and histopathologic features of oral and sinonasal melanoma.

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  5 in total

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2.  Amelanotic Malignant Mucosal Melanoma of the Nasal Cavity: Case Report and Literature Review.

Authors:  Ilias Tahiri; Othman El Houari; Amal Hajjij; Mohammed Zalagh; Fouad Benariba
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3.  Melanoma of the Sinonasal Tract: Value of a Septate Pattern on Precontrast T1-Weighted MR Imaging.

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Journal:  AJNR Am J Neuroradiol       Date:  2018-01-25       Impact factor: 3.825

Review 4.  Update on primary head and neck mucosal melanoma.

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5.  Intratumoral Heterogeneity of MAGE-C1/CT7 and MAGE-C2/CT10 Expression in Mucosal Melanoma.

Authors:  A Curioni-Fontecedro; R Pitocco; N L Schoenewolf; D Holzmann; D Soldini; R Dummer; S Calvieri; H Moch; D Mihic-Probst; A Fitsche
Journal:  Biomed Res Int       Date:  2015-06-16       Impact factor: 3.411
  5 in total

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