| Literature DB >> 22548480 |
Gui-Hua Tang1, Yu Zhang, Yu-Cheng Gu, Shi-Fei Li, Ying-Tong Di, Yue-Hu Wang, Cui-Xian Yang, Guo-Ying Zuo, Shun-Lin Li, Hong-Ping He, Xiao-Jiang Hao.
Abstract
Trigoflavidols A (1) and B (2), tetranorditerpenoid dimers possessing a rearrangement skeleton with a spiroketal core moiety, and trigoflavidol C (3), a hexanorditerpenoid, have been isolated from Trigonostemon flavidus along with two known compounds. Compounds 1 and 2 showed moderate antimicrobial activities (MIC values: 3.12-6.25 μg/mL) against Staphylococcus aureus, 8(#)MRSA, and 82(#)MRSA, and 1, 2, and 5 showed weak activities (IC(50) values: 3.75-28.99 μM) against various human tumor cell lines.Entities:
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Year: 2012 PMID： 22548480 DOI： 10.1021/np3001128
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050