BACKGROUND: This study examined stability of remission in patients who were abstainers and non-problem users at 1-year after entering private, outpatient alcohol and drug treatment. We examined: (a) How does risk of relapse change over time? (b) What was the risk of relapse for non-problem users versus abstainers? (c) What individual, treatment, and extra-treatment characteristics predicted time to relapse, and did these differ by non-problem use versus abstinence? METHODS: The sample consisted of 684 adults in remission (i.e., abstainers or non-problem users) 1 year following treatment intake. Participants were interviewed at intake, and 1, 5, 7, 9, and 11 years after intake. We used discrete-time survival analysis to examine when relapse is most likely to occur and predictors of relapse. RESULTS: Relapse was most likely at 5-year, and least likely at 11-year follow-up. Non-problem users had twice the odds of relapse compared to abstainers. Younger individuals and those with fewer 12-step meetings and shorter index treatment had higher odds of relapse than others. We found no significant interactions between non-problem use and the other covariates suggesting that significant predictors of outcome did not differ for non-problem users. CONCLUSIONS: Non-problem use is not an optimal 1-year outcome for those in an abstinence-oriented, heterogeneous substance use treatment program. Future research should examine whether these results are found in harm reduction treatment and self-help models, or in those with less severe problems. Results suggest treatment retention and 12-step participation are prognostic markers of long-term positive outcomes for those achieving remission at 1 year.
BACKGROUND: This study examined stability of remission in patients who were abstainers and non-problem users at 1-year after entering private, outpatientalcohol and drug treatment. We examined: (a) How does risk of relapse change over time? (b) What was the risk of relapse for non-problem users versus abstainers? (c) What individual, treatment, and extra-treatment characteristics predicted time to relapse, and did these differ by non-problem use versus abstinence? METHODS: The sample consisted of 684 adults in remission (i.e., abstainers or non-problem users) 1 year following treatment intake. Participants were interviewed at intake, and 1, 5, 7, 9, and 11 years after intake. We used discrete-time survival analysis to examine when relapse is most likely to occur and predictors of relapse. RESULTS: Relapse was most likely at 5-year, and least likely at 11-year follow-up. Non-problem users had twice the odds of relapse compared to abstainers. Younger individuals and those with fewer 12-step meetings and shorter index treatment had higher odds of relapse than others. We found no significant interactions between non-problem use and the other covariates suggesting that significant predictors of outcome did not differ for non-problem users. CONCLUSIONS: Non-problem use is not an optimal 1-year outcome for those in an abstinence-oriented, heterogeneous substance use treatment program. Future research should examine whether these results are found in harm reduction treatment and self-help models, or in those with less severe problems. Results suggest treatment retention and 12-step participation are prognostic markers of long-term positive outcomes for those achieving remission at 1 year.
Authors: Constance Weisner; G Thomas Ray; Jennifer R Mertens; Derek D Satre; Charles Moore Journal: Drug Alcohol Depend Date: 2003-09-10 Impact factor: 4.492
Authors: Andrea H Kline-Simon; Felicia W Chi; Jennifer R Mertens; Constance Weisner Journal: Am J Drug Alcohol Abuse Date: 2017-02-16 Impact factor: 3.829
Authors: Erin J Stringfellow; Theresa W Kim; Adam J Gordon; David E Pollio; Richard A Grucza; Erika L Austin; N Kay Johnson; Stefan G Kertesz Journal: Subst Abus Date: 2016-02-25 Impact factor: 3.716
Authors: Katherine E Watkins; Allison J Ober; Karen Lamp; Mimi Lind; Claude Setodji; Karen Chan Osilla; Sarah B Hunter; Colleen M McCullough; Kirsten Becker; Praise O Iyiewuare; Allison Diamant; Keith Heinzerling; Harold Alan Pincus Journal: JAMA Intern Med Date: 2017-10-01 Impact factor: 21.873
Authors: Vivia V McCutcheon; Marc A Schuckit; John R Kramer; Grace Chan; Howard J Edenberg; Tom L Smith; Annah K Bender; Victor Hesselbrock; Michie Hesselbrock; Kathleen K Bucholz Journal: Addiction Date: 2017-07-06 Impact factor: 6.526