SETTING: Basic epidemiological information on childhood cancer in Western Kenya is lacking. This deficit obstructs efforts to improve the care and survival rates of children in this part of the world. OBJECTIVE: Our study provides an overview of childhood cancer patients presenting for treatment in Western Kenya. DESIGN: A retrospective analysis of childhood cancer patients presenting for treatment in Western Kenya was carried out using information from three separate databases at the Moi Teaching and Referral Hospital in Eldoret. All patients aged 0-19 years first presenting between January 2006 and January 2010 with a newly diagnosed malignancy were included. RESULTS: A total of 436 children with cancer were registered during the period. There were 256 (59%) boys and 180 (41%) girls with a male/female ratio of 1.4:1. The group aged 6-10 years contained most children (29%). Median age at admission was 8 years. Non-Hodgkin's lymphoma was the most common type of cancer (34%), followed by acute lymphoblastic leukaemia (15%), Hodgkin's lymphoma (8%), nephroblastoma (8%), rhabdomyosarcoma (7%), retinoblastoma (5%) and Kaposi's sarcoma (5%). Only four (1%) children with brain tumours were documented. Ewing's sarcoma was not diagnosed. CONCLUSIONS: Our study provides an overview of childhood cancer patients presenting for treatment in Western Kenya. The distribution of malignancies is similar to findings from other equatorial African countries but differs markedly from studies in high-income countries. The new comprehensive cancer registration system will be continued and extended to serve as the basis for an evidence-based oncology program. Eventually this may lead to improved clinical outcomes.
SETTING: Basic epidemiological information on childhood cancer in Western Kenya is lacking. This deficit obstructs efforts to improve the care and survival rates of children in this part of the world. OBJECTIVE: Our study provides an overview of childhood cancerpatients presenting for treatment in Western Kenya. DESIGN: A retrospective analysis of childhood cancerpatients presenting for treatment in Western Kenya was carried out using information from three separate databases at the Moi Teaching and Referral Hospital in Eldoret. All patients aged 0-19 years first presenting between January 2006 and January 2010 with a newly diagnosed malignancy were included. RESULTS: A total of 436 children with cancer were registered during the period. There were 256 (59%) boys and 180 (41%) girls with a male/female ratio of 1.4:1. The group aged 6-10 years contained most children (29%). Median age at admission was 8 years. Non-Hodgkin's lymphoma was the most common type of cancer (34%), followed by acute lymphoblastic leukaemia (15%), Hodgkin's lymphoma (8%), nephroblastoma (8%), rhabdomyosarcoma (7%), retinoblastoma (5%) and Kaposi's sarcoma (5%). Only four (1%) children with brain tumours were documented. Ewing's sarcoma was not diagnosed. CONCLUSIONS: Our study provides an overview of childhood cancerpatients presenting for treatment in Western Kenya. The distribution of malignancies is similar to findings from other equatorial African countries but differs markedly from studies in high-income countries. The new comprehensive cancer registration system will be continued and extended to serve as the basis for an evidence-based oncology program. Eventually this may lead to improved clinical outcomes.
Authors: Jason Axt; Fatmah Abdallah; Meridith Axt; Jessie Githanga; Erik Hansen; Joel Lessan; Ming Li; Joyce Musimbi; Michael Mwachiro; Mark Newton; James Ndung'u; Festis Njuguna; Ancent Nzioka; Oliver Oruko; Kirtika Patel; Robert Tenge; Flora Ukoli; Russel White; James A O'Neill; Harold N Lovvorn Journal: J Pediatr Surg Date: 2013-06 Impact factor: 2.545
Authors: Gilbert Olbara; H A Martijn; F Njuguna; S Langat; S Martin; J Skiles; T Vik; G J L Kaspers; S Mostert Journal: Support Care Cancer Date: 2019-06-07 Impact factor: 3.603
Authors: F Njuguna; S Mostert; A Seijffert; J Musimbi; S Langat; R H M van der Burgt; J Skiles; M N Sitaresmi; P M van de Ven; G J L Kaspers Journal: Support Care Cancer Date: 2014-10-17 Impact factor: 3.603
Authors: Chris A Rees; Elizabeth M Keating; Heather Lukolyo; Heather E Danysh; Michael E Scheurer; Parth S Mehta; Joseph Lubega; Jeremy S Slone Journal: Pediatr Blood Cancer Date: 2016-04-15 Impact factor: 3.167
Authors: Jodi L Skiles; ChienWei Chiang; Claire H Li; Steve Martin; Ellen L Smith; Gilbert Olbara; David R Jones; Terry A Vik; Saskia Mostert; Floor Abbink; Gertjan J Kaspers; Lang Li; Festus Njuguna; Tammy J Sajdyk; Jamie L Renbarger Journal: Pediatr Blood Cancer Date: 2017-11-08 Impact factor: 3.167
Authors: Marilyn Keng-Nasang Mbi Feh; Kristopher A Lyon; Ankita V Brahmaroutu; Ramya Tadipatri; Ekokobe Fonkem Journal: Neurooncol Pract Date: 2021-01-27
Authors: Hugo A Martijn; Festus Njuguna; Gilbert Olbara; Sandra Langat; Jodi Skiles; Stephen Martin; Terry Vik; Peter M van de Ven; Gertjan Jl Kaspers; Saskia Mostert Journal: BMJ Paediatr Open Date: 2017-08-11
Authors: Jeremy S Slone; Amanda K Slone; Oaitse Wally; Pearl Semetsa; Mpho Raletshegwana; Susan Alisanski; Lisa M Force; Kamusisi Chinyundo; Judith Margolin; Anurag K Agrawal; Alan R Anderson; Michael E Scheurer; Parth S Mehta Journal: J Glob Oncol Date: 2018-09