Literature DB >> 22535237

Epidemiology of diagnosed childhood cancer in Western Kenya.

Saskia Mostert1, Festus Njuguna, Luc Kemps, Matthew Strother, Louise Aluoch, Gyabi Buziba, Gertjan Kaspers.   

Abstract

SETTING: Basic epidemiological information on childhood cancer in Western Kenya is lacking. This deficit obstructs efforts to improve the care and survival rates of children in this part of the world.
OBJECTIVE: Our study provides an overview of childhood cancer patients presenting for treatment in Western Kenya.
DESIGN: A retrospective analysis of childhood cancer patients presenting for treatment in Western Kenya was carried out using information from three separate databases at the Moi Teaching and Referral Hospital in Eldoret. All patients aged 0-19 years first presenting between January 2006 and January 2010 with a newly diagnosed malignancy were included.
RESULTS: A total of 436 children with cancer were registered during the period. There were 256 (59%) boys and 180 (41%) girls with a male/female ratio of 1.4:1. The group aged 6-10 years contained most children (29%). Median age at admission was 8 years. Non-Hodgkin's lymphoma was the most common type of cancer (34%), followed by acute lymphoblastic leukaemia (15%), Hodgkin's lymphoma (8%), nephroblastoma (8%), rhabdomyosarcoma (7%), retinoblastoma (5%) and Kaposi's sarcoma (5%). Only four (1%) children with brain tumours were documented. Ewing's sarcoma was not diagnosed.
CONCLUSIONS: Our study provides an overview of childhood cancer patients presenting for treatment in Western Kenya. The distribution of malignancies is similar to findings from other equatorial African countries but differs markedly from studies in high-income countries. The new comprehensive cancer registration system will be continued and extended to serve as the basis for an evidence-based oncology program. Eventually this may lead to improved clinical outcomes.

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Year:  2012        PMID: 22535237     DOI: 10.1136/archdischild-2011-300829

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN: 0003-9888            Impact factor:   3.791


  9 in total

1.  Wilms tumor survival in Kenya.

Authors:  Jason Axt; Fatmah Abdallah; Meridith Axt; Jessie Githanga; Erik Hansen; Joel Lessan; Ming Li; Joyce Musimbi; Michael Mwachiro; Mark Newton; James Ndung'u; Festis Njuguna; Ancent Nzioka; Oliver Oruko; Kirtika Patel; Robert Tenge; Flora Ukoli; Russel White; James A O'Neill; Harold N Lovvorn
Journal:  J Pediatr Surg       Date:  2013-06       Impact factor: 2.545

2.  Influence of health insurance status on childhood cancer treatment outcomes in Kenya.

Authors:  Gilbert Olbara; H A Martijn; F Njuguna; S Langat; S Martin; J Skiles; T Vik; G J L Kaspers; S Mostert
Journal:  Support Care Cancer       Date:  2019-06-07       Impact factor: 3.603

3.  Parental experiences of childhood cancer treatment in Kenya.

Authors:  F Njuguna; S Mostert; A Seijffert; J Musimbi; S Langat; R H M van der Burgt; J Skiles; M N Sitaresmi; P M van de Ven; G J L Kaspers
Journal:  Support Care Cancer       Date:  2014-10-17       Impact factor: 3.603

Review 4.  Mapping the Epidemiology of Kaposi Sarcoma and Non-Hodgkin Lymphoma Among Children in Sub-Saharan Africa: A Review.

Authors:  Chris A Rees; Elizabeth M Keating; Heather Lukolyo; Heather E Danysh; Michael E Scheurer; Parth S Mehta; Joseph Lubega; Jeremy S Slone
Journal:  Pediatr Blood Cancer       Date:  2016-04-15       Impact factor: 3.167

5.  CYP3A5 genotype and its impact on vincristine pharmacokinetics and development of neuropathy in Kenyan children with cancer.

Authors:  Jodi L Skiles; ChienWei Chiang; Claire H Li; Steve Martin; Ellen L Smith; Gilbert Olbara; David R Jones; Terry A Vik; Saskia Mostert; Floor Abbink; Gertjan J Kaspers; Lang Li; Festus Njuguna; Tammy J Sajdyk; Jamie L Renbarger
Journal:  Pediatr Blood Cancer       Date:  2017-11-08       Impact factor: 3.167

6.  The need for a central brain tumor registry in Africa: A review of central nervous system tumors in Africa from 1960 to 2017.

Authors:  Marilyn Keng-Nasang Mbi Feh; Kristopher A Lyon; Ankita V Brahmaroutu; Ramya Tadipatri; Ekokobe Fonkem
Journal:  Neurooncol Pract       Date:  2021-01-27

7.  Integrating stages of change models to cast new vision on interventions to improve global retinoblastoma and childhood cancer outcomes.

Authors:  Meaghann S Weaver; Christina L Heminger; Catherine G Lam
Journal:  BMC Public Health       Date:  2014-09-11       Impact factor: 3.295

8.  Influence of health insurance status on paediatric non-Hodgkin's lymphoma treatment in Kenya.

Authors:  Hugo A Martijn; Festus Njuguna; Gilbert Olbara; Sandra Langat; Jodi Skiles; Stephen Martin; Terry Vik; Peter M van de Ven; Gertjan Jl Kaspers; Saskia Mostert
Journal:  BMJ Paediatr Open       Date:  2017-08-11

9.  Establishing a Pediatric Hematology-Oncology Program in Botswana.

Authors:  Jeremy S Slone; Amanda K Slone; Oaitse Wally; Pearl Semetsa; Mpho Raletshegwana; Susan Alisanski; Lisa M Force; Kamusisi Chinyundo; Judith Margolin; Anurag K Agrawal; Alan R Anderson; Michael E Scheurer; Parth S Mehta
Journal:  J Glob Oncol       Date:  2018-09
  9 in total

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