Marilyn Keng-Nasang Mbi Feh1, Kristopher A Lyon2, Ankita V Brahmaroutu3, Ramya Tadipatri4, Ekokobe Fonkem4. 1. Windsor University School of Medicine, Cayon St. Kitts, West Indies. 2. Department of Neurosurgery, Baylor Scott & White Health, Temple, Texas, USA. 3. Texas A&M University College of Medicine, Bryan, Texas, USA. 4. Department of Neurology, Barrow Neurological Institute, Phoenix, Arizona, USA.
Abstract
BACKGROUND: Central nervous system (CNS) tumors pose a substantial health problem. Although data on specific time periods and regions of Africa have been previously reported, no study has yet to provide a systematic review of CNS tumors for the entire continent of Africa. This study aims to analyze the frequency of CNS tumors in Africa from 1960 to 2017. METHODS: A comprehensive literature search on CNS tumors in Africa was performed using multiple online scientific databases. The following keywords were queried in combination with the phrase "CNS tumors in Africa": incidence, frequency, epidemiology, prevalence, brain, and cancer. A total of 26 articles met the inclusion criteria. Each selected article reported incidence and mortality rates from different regions of Africa in a time period between 1960 and 2017. SPSS21 statistical software was used to analyze the data. RESULTS: Nigeria, Egypt, and Uganda were found to have the most of the cases of CNS tumors in Africa. Males made up 54% of the 5902 cases per 100 000 population. The most common CNS tumors found were astrocytoma (24.70%), meningioma (22.22%), pituitary adenoma (8.4%), medulloblastoma (4.26%), craniopharyngioma (4.07%), and other not specified (25.17%). CONCLUSIONS: Given the large population of Africa, the total reported cases may be underestimated when compared with other continents due to the lack of a central brain tumor registry in Africa. A comprehensive knowledge of CNS tumors in Africa is critical to population-based research and improving the current healthcare system.
BACKGROUND: Central nervous system (CNS) tumors pose a substantial health problem. Although data on specific time periods and regions of Africa have been previously reported, no study has yet to provide a systematic review of CNS tumors for the entire continent of Africa. This study aims to analyze the frequency of CNS tumors in Africa from 1960 to 2017. METHODS: A comprehensive literature search on CNS tumors in Africa was performed using multiple online scientific databases. The following keywords were queried in combination with the phrase "CNS tumors in Africa": incidence, frequency, epidemiology, prevalence, brain, and cancer. A total of 26 articles met the inclusion criteria. Each selected article reported incidence and mortality rates from different regions of Africa in a time period between 1960 and 2017. SPSS21 statistical software was used to analyze the data. RESULTS: Nigeria, Egypt, and Uganda were found to have the most of the cases of CNS tumors in Africa. Males made up 54% of the 5902 cases per 100 000 population. The most common CNS tumors found were astrocytoma (24.70%), meningioma (22.22%), pituitary adenoma (8.4%), medulloblastoma (4.26%), craniopharyngioma (4.07%), and other not specified (25.17%). CONCLUSIONS: Given the large population of Africa, the total reported cases may be underestimated when compared with other continents due to the lack of a central brain tumor registry in Africa. A comprehensive knowledge of CNS tumors in Africa is critical to population-based research and improving the current healthcare system.
Authors: Khaled R Zalata; Dina A El-Tantawy; Azza Abdel-Aziz; Abdel-Wahab M Ibraheim; Ahmed H Halaka; Hasan H Gawish; Mohamed Safwat; Nabil Mansour; Mohammad Mansour; Abdelhadi Shebl Journal: Indian J Pathol Microbiol Date: 2011 Apr-Jun Impact factor: 0.740
Authors: Ulrick Sidney Kanmounye; Claire Karekezi; Arsene Daniel Nyalundja; Ahmed K Awad; Tsegazeab Laeke; James A Balogun Journal: Neuro Oncol Date: 2022-10-03 Impact factor: 13.029