Literature DB >> 22534870

Electronic medical records as a tool in clinical pharmacology: opportunities and challenges.

D M Roden1, H Xu, J C Denny, R A Wilke.   

Abstract

The development and increasing sophistication of electronic medical record (EMR) systems hold the promise of not only improving patient care but also providing unprecedented opportunities for discovery in the fields of basic, translational, and implementation sciences. Clinical pharmacology research in the EMR environment has only recently started to become a reality, with EMRs becoming increasingly populated, methods to mine drug response and other phenotypes becoming more sophisticated, and links being established with DNA repositories.

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Year:  2012        PMID： 22534870      PMCID： PMC3819803          DOI： 10.1038/clpt.2012.42

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN： 0009-9236            Impact factor:   6.875


  39 in total

1.  Comparative-effectiveness research in distributed health data networks.

Authors:  S Toh; R Platt; J F Steiner; J S Brown
Journal:  Clin Pharmacol Ther       Date:  2011-10-26       Impact factor: 6.875

2.  Adopting real-time surveillance dashboards as a component of an enterprisewide medication safety strategy.

Authors:  Lemuel R Waitman; Ira E Phillips; Allison B McCoy; Ioana Danciu; Robert M Halpenny; Cori L Nelsen; Daniel C Johnson; John M Starmer; Josh F Peterson
Journal:  Jt Comm J Qual Patient Saf       Date:  2011-07

3.  Complement receptor 1 gene variants are associated with erythrocyte sedimentation rate.

Authors:  Iftikhar J Kullo; Keyue Ding; Khader Shameer; Catherine A McCarty; Gail P Jarvik; Joshua C Denny; Marylyn D Ritchie; Zi Ye; David R Crosslin; Rex L Chisholm; Teri A Manolio; Christopher G Chute
Journal:  Am J Hum Genet       Date:  2011-06-23       Impact factor: 11.025

4.  Developing the Sentinel System--a national resource for evidence development.

Authors:  Rachel E Behrman; Joshua S Benner; Jeffrey S Brown; Mark McClellan; Janet Woodcock; Richard Platt
Journal:  N Engl J Med       Date:  2011-01-12       Impact factor: 91.245

Review 5.  Using electronic health records to drive discovery in disease genomics.

Authors:  Isaac S Kohane
Journal:  Nat Rev Genet       Date:  2011-05-18       Impact factor: 53.242

6.  Facilitating pharmacogenetic studies using electronic health records and natural-language processing: a case study of warfarin.

Authors:  Hua Xu; Min Jiang; Matt Oetjens; Erica A Bowton; Andrea H Ramirez; Janina M Jeff; Melissa A Basford; Jill M Pulley; James D Cowan; Xiaoming Wang; Marylyn D Ritchie; Daniel R Masys; Dan M Roden; Dana C Crawford; Joshua C Denny
Journal:  J Am Med Inform Assoc       Date:  2011 Jul-Aug       Impact factor: 4.497

7.  Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome- and phenome-wide studies.

Authors:  Joshua C Denny; Dana C Crawford; Marylyn D Ritchie; Suzette J Bielinski; Melissa A Basford; Yuki Bradford; High Seng Chai; Lisa Bastarache; Rebecca Zuvich; Peggy Peissig; David Carrell; Andrea H Ramirez; Jyotishman Pathak; Russell A Wilke; Luke Rasmussen; Xiaoming Wang; Jennifer A Pacheco; Abel N Kho; M Geoffrey Hayes; Noah Weston; Martha Matsumoto; Peter A Kopp; Katherine M Newton; Gail P Jarvik; Rongling Li; Teri A Manolio; Iftikhar J Kullo; Christopher G Chute; Rex L Chisholm; Eric B Larson; Catherine A McCarty; Daniel R Masys; Dan M Roden; Mariza de Andrade
Journal:  Am J Hum Genet       Date:  2011-10-07       Impact factor: 11.025

8.  Detecting drug interactions from adverse-event reports: interaction between paroxetine and pravastatin increases blood glucose levels.

Authors:  N P Tatonetti; J C Denny; S N Murphy; G H Fernald; G Krishnan; V Castro; P Yue; P S Tsao; P S Tsau; I Kohane; D M Roden; R B Altman
Journal:  Clin Pharmacol Ther       Date:  2011-05-25       Impact factor: 6.875

9.  Genetic basis of autoantibody positive and negative rheumatoid arthritis risk in a multi-ethnic cohort derived from electronic health records.

Authors:  Fina Kurreeman; Katherine Liao; Lori Chibnik; Brendan Hickey; Eli Stahl; Vivian Gainer; Gang Li; Lynn Bry; Scott Mahan; Kristin Ardlie; Brian Thomson; Peter Szolovits; Susanne Churchill; Shawn N Murphy; Tianxi Cai; Soumya Raychaudhuri; Isaac Kohane; Elizabeth Karlson; Robert M Plenge
Journal:  Am J Hum Genet       Date:  2011-01-07       Impact factor: 11.025

10.  Electronic medical records for genetic research: results of the eMERGE consortium.

Authors:  Abel N Kho; Jennifer A Pacheco; Peggy L Peissig; Luke Rasmussen; Katherine M Newton; Noah Weston; Paul K Crane; Jyotishman Pathak; Christopher G Chute; Suzette J Bielinski; Iftikhar J Kullo; Rongling Li; Teri A Manolio; Rex L Chisholm; Joshua C Denny
Journal:  Sci Transl Med       Date:  2011-04-20       Impact factor: 17.956
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  22 in total

1.  Combining billing codes, clinical notes, and medications from electronic health records provides superior phenotyping performance.

Authors:  Wei-Qi Wei; Pedro L Teixeira; Huan Mo; Robert M Cronin; Jeremy L Warner; Joshua C Denny
Journal:  J Am Med Inform Assoc       Date:  2015-09-02       Impact factor: 4.497

Review 2.  Intelligent use and clinical benefits of electronic health records in rheumatoid arthritis.

Authors:  Robert J Carroll; Anne E Eyler; Joshua C Denny
Journal:  Expert Rev Clin Immunol       Date:  2015-02-08       Impact factor: 4.473

3.  PheKB: a catalog and workflow for creating electronic phenotype algorithms for transportability.

Authors:  Jacqueline C Kirby; Peter Speltz; Luke V Rasmussen; Melissa Basford; Omri Gottesman; Peggy L Peissig; Jennifer A Pacheco; Gerard Tromp; Jyotishman Pathak; David S Carrell; Stephen B Ellis; Todd Lingren; Will K Thompson; Guergana Savova; Jonathan Haines; Dan M Roden; Paul A Harris; Joshua C Denny
Journal:  J Am Med Inform Assoc       Date:  2016-03-28       Impact factor: 4.497

Review 4.  Systems medicine: evolution of systems biology from bench to bedside.

Authors:  Rui-Sheng Wang; Bradley A Maron; Joseph Loscalzo
Journal:  Wiley Interdiscip Rev Syst Biol Med       Date:  2015-04-17

5.  Design patterns for the development of electronic health record-driven phenotype extraction algorithms.

Authors:  Luke V Rasmussen; Will K Thompson; Jennifer A Pacheco; Abel N Kho; David S Carrell; Jyotishman Pathak; Peggy L Peissig; Gerard Tromp; Joshua C Denny; Justin B Starren
Journal:  J Biomed Inform       Date:  2014-06-21       Impact factor: 6.317

Review 6.  Cardiovascular pharmacogenomics: the future of cardiovascular therapeutics?

Authors:  Dan M Roden
Journal:  Can J Cardiol       Date:  2012-11-27       Impact factor: 5.223

Review 7.  Stem cell therapy for chronic heart failure: an updated appraisal.

Authors:  Simon Maltais; Steven J Joggerst; Antonis Hatzopoulos; Thomas G DiSalvo; David Zhao; Hak-Joon Sung; Xintong Wang; John G Byrne; Allen J Naftilan
Journal:  Expert Opin Biol Ther       Date:  2013-01-06       Impact factor: 4.388

8.  Inclusion of pediatric samples in an opt-out biorepository linking DNA to de-identified medical records: pediatric BioVU.

Authors:  T L McGregor; S L Van Driest; K B Brothers; E A Bowton; L J Muglia; D M Roden
Journal:  Clin Pharmacol Ther       Date:  2012-11-21       Impact factor: 6.875

9.  Ease of adoption of clinical natural language processing software: An evaluation of five systems.

Authors:  Kai Zheng; V G Vinod Vydiswaran; Yang Liu; Yue Wang; Amber Stubbs; Özlem Uzuner; Anupama E Gururaj; Samuel Bayer; John Aberdeen; Anna Rumshisky; Serguei Pakhomov; Hongfang Liu; Hua Xu
Journal:  J Biomed Inform       Date:  2015-07-22       Impact factor: 6.317

10.  Integrating pharmacogenomics into the electronic health record by implementing genomic indicators.

Authors:  Pedro J Caraballo; Joseph A Sutton; Jyothsna Giri; Jessica A Wright; Wayne T Nicholson; Iftikhar J Kullo; Mark A Parkulo; Suzette J Bielinski; Ann M Moyer
Journal:  J Am Med Inform Assoc       Date:  2020-01-01       Impact factor: 4.497
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