Literature DB >> 22534678

[Botulinum toxin A after microvascular ALT flap in a patient with (corrected) squamous cell carcinoma of the tongue].

F Ihler1, R Laskawi, C Matthias, H H Rustenbeck, M Canis.   

Abstract

We report the case of a 23-year-old man presenting with a cT4 cN1 M0squamous cell carcinoma of the right tongue. After tumor resection and covering of the defect with a microvascular anterolateral thigh (ALT) flap, the patient showed distinct drooling without any substantial regression after anticholinergic therapy. For this reason 75 units of Botox® were injected into the submandibular and parotid glands. After the intraglandular injections, good reduction of saliva secretion was achieved. The treatment improved flap healing, aspiration and patient satisfaction. Injection of botulinum toxin A into the salivary glands is a sufficient therapy for postoperative hypersalivation.

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Year:  2012        PMID: 22534678     DOI: 10.1007/s00106-011-2476-8

Source DB:  PubMed          Journal:  HNO        ISSN: 0017-6192            Impact factor:   1.284


  8 in total

1.  Botulinum toxin to reduce saliva flow: selected indications for ultrasound-guided toxin application into salivary glands.

Authors:  Maik Ellies; Rainer Laskawi; Saskia Rohrbach-Volland; Christian Arglebe; Wolfgang Beuche
Journal:  Laryngoscope       Date:  2002-01       Impact factor: 3.325

2.  Up-to-date report of botulinum toxin type A treatment in patients with gustatory sweating (Frey's syndrome).

Authors:  R Laskawi; C Drobik; C Schönebeck
Journal:  Laryngoscope       Date:  1998-03       Impact factor: 3.325

3.  Frey's syndrome: treatment with botulinum toxin.

Authors:  C Drobik; R Laskawi
Journal:  Acta Otolaryngol       Date:  1995-05       Impact factor: 1.494

Review 4.  Interventions for the treatment of oral and oropharyngeal cancers: surgical treatment.

Authors:  Alyson Bessell; Anne-Marie Glenny; Susan Furness; Jan E Clarkson; Richard Oliver; David I Conway; Michaelina Macluskey; Sue Pavitt; Philip Sloan; Helen V Worthington
Journal:  Cochrane Database Syst Rev       Date:  2011-09-07

5.  Have we found an ideal soft-tissue flap? An experience with 672 anterolateral thigh flaps.

Authors:  Fu-chan Wei; Vivek Jain; Naci Celik; Hung-chi Chen; David Chwei-Chin Chuang; Chih-hung Lin
Journal:  Plast Reconstr Surg       Date:  2002-06       Impact factor: 4.730

6.  Botulinum toxin prevents radiotherapy-induced salivary gland damage.

Authors:  Afshin Teymoortash; Felix Müller; Janko Juricko; Michael Bieker; Robert Mandic; Damiano Librizzi; Helmut Höffken; Andeas Pfestroff; Jochen Alfred Werner
Journal:  Oral Oncol       Date:  2009-02-11       Impact factor: 5.337

7.  The free thigh flap: a new free flap concept based on the septocutaneous artery.

Authors:  Y G Song; G Z Chen; Y L Song
Journal:  Br J Plast Surg       Date:  1984-04

Review 8.  Management of salivary flow in head and neck cancer patients--a systematic review.

Authors:  Steven R Bomeli; Shaun C Desai; Jonas T Johnson; Rohan R Walvekar
Journal:  Oral Oncol       Date:  2008-05-16       Impact factor: 5.337

  8 in total
  3 in total

Review 1.  [Botulinum toxin in otorhinolaryngology - an update].

Authors:  R Laskawi; A Olthoff
Journal:  HNO       Date:  2017-10       Impact factor: 1.284

Review 2.  Botulinum toxin A is an effective therapeutic tool for the management of parotid sialocele and fistula: A systematic review.

Authors:  Shivesh Maharaj; Sheetal Mungul; Abdullah Laher
Journal:  Laryngoscope Investig Otolaryngol       Date:  2020-01-23

Review 3.  Botulinum Neurotoxins and Cancer-A Review of the Literature.

Authors:  Shivam Om Mittal; Bahman Jabbari
Journal:  Toxins (Basel)       Date:  2020-01-05       Impact factor: 4.546

  3 in total

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