Literature DB >> 22533633

A new lignan with anti-tumour activity from Polygonum perfoliatum L.

Kui-Wu Wang1, Jun-Ru Zhu, Lian-Qing Shen.   

Abstract

The methanol extract of the tubers of Polygonum perfoliatum L. afforded a new lignan: 8-oxo-pinoresinol (1), and five known compounds 3',5-dihydroxy-3,4',5',7-tetramethoxy-flavone (2), catechin (3), quercetin (4), quercetin-3-O-β-D-glucuronide (5) and rutin (6). Their structures were established by MS, one- and two-dimensional NMR experiments. Compound 1 showed cytotoxicity against human mammary carcinoma (Bcap-37), human colon carcinoma (RKO), human hepatocellular carcinoma (SMMC-7721), human prostate carcinoma (PC3) and human erythroleukaemia (K562) cells.

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Year:  2012        PMID: 22533633     DOI: 10.1080/14786419.2012.682993

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN: 1478-6419            Impact factor:   2.861


  1 in total

1.  Heavy metals analysis, phytochemical, phytotoxic and anthelmintic investigations of crude methanolic extract, subsequent fractions and crude saponins from Polygonum hydropiper L.

Authors:  Muhammad Ayaz; Muhammad Junaid; Fazal Subhan; Farhat Ullah; Abdul Sadiq; Sajjad Ahmad; Muhammad Imran; Zul Kamal; Sajid Hussain; Syed Majid Shah
Journal:  BMC Complement Altern Med       Date:  2014-12-03       Impact factor: 3.659

  1 in total

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