Literature DB >> 22531827

Conformations of individual quadruplex units studied in the context of extended human telomeric DNA.

Vijay Singh1, Mykhailo Azarkh, Malte Drescher, Jörg S Hartig.   

Abstract

G-quadruplex conformations within a sequence of three quadruplex units of human telomeric DNA were studied by two-frequency pulsed electron paramagnetic resonance (EPR) spectroscopy. In contrast to some individual G-quadruplexes, within the higher-order human telomeric sequence a (3+1) hybrid structure is formed.

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Year:  2012        PMID： 22531827     DOI： 10.1039/c2cc32012f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  9 in total

1.  Site-directed spin-labeling of nucleotides and the use of in-cell EPR to determine long-range distances in a biologically relevant environment.

Authors:  Mykhailo Azarkh; Vijay Singh; Oliver Okle; Isabelle T Seemann; Daniel R Dietrich; Jörg S Hartig; Malte Drescher
Journal:  Nat Protoc       Date:  2012-12-20       Impact factor: 13.491

2.  G-quadruplex conformation and dynamics are determined by loop length and sequence.

Authors:  Ramreddy Tippana; Weikun Xiao; Sua Myong
Journal:  Nucleic Acids Res       Date:  2014-06-11       Impact factor: 16.971

3.  G-quadruplexes are specifically recognized and distinguished by selected designed ankyrin repeat proteins.

Authors:  Oliver Scholz; Simon Hansen; Andreas Plückthun
Journal:  Nucleic Acids Res       Date:  2014-07-22       Impact factor: 16.971

4.  Distance measurements between paramagnetic ligands bound to parallel stranded guanine quadruplexes.

Authors:  M P Donohue; V A Szalai
Journal:  Phys Chem Chem Phys       Date:  2016-06-01       Impact factor: 3.676

5.  The solution structures of higher-order human telomere G-quadruplex multimers.

Authors:  Robert C Monsen; Srinivas Chakravarthy; William L Dean; Jonathan B Chaires; John O Trent
Journal:  Nucleic Acids Res       Date:  2021-02-22       Impact factor: 19.160

6.  Mutational Dissection of Telomeric DNA Binding Requirements of G4 Resolvase 1 Shows that G4-Structure and Certain 3'-Tail Sequences Are Sufficient for Tight and Complete Binding.

Authors:  Philip J Smaldino; Eric D Routh; Jung H Kim; Banabihari Giri; Steven D Creacy; Roy R Hantgan; Steven A Akman; James P Vaughn
Journal:  PLoS One       Date:  2015-07-14       Impact factor: 3.240

7.  G-quadruplex formation in telomeres enhances POT1/TPP1 protection against RPA binding.

Authors:  Sujay Ray; Jigar N Bandaria; Mohammad H Qureshi; Ahmet Yildiz; Hamza Balci
Journal:  Proc Natl Acad Sci U S A       Date:  2014-02-10       Impact factor: 12.779

8.  The exception that confirms the rule: a higher-order telomeric G-quadruplex structure more stable in sodium than in potassium.

Authors:  Carole Saintomé; Samir Amrane; Jean-Louis Mergny; Patrizia Alberti
Journal:  Nucleic Acids Res       Date:  2016-01-13       Impact factor: 16.971

9.  Evaluation of the interaction between long telomeric DNA and macrocyclic hexaoxazole (6OTD) dimer of a G-quadruplex ligand.

Authors:  Keisuke Iida; Satoki Majima; Takahiro Nakamura; Hiroyuki Seimiya; Kazuo Nagasawa
Journal:  Molecules       Date:  2013-04-12       Impact factor: 4.411
  9 in total

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