Literature DB >> 22531481

Platelet counts and coagulation tests prior to neuraxial anesthesia in patients with preeclampsia: a retrospective analysis.

Pervez Sultan1, Alexander Butwick.   

Abstract

This retrospective, descriptive study aimed to assess hematologic testing practices in 100 patients with preeclampsia undergoing neuraxial blockade (NB). Prior to NB, platelet (PLT) count was performed in 61 (98%) of 62 women in labor and in 37 (97%) of 38 women undergoing cesarean delivery (CD). No patients had a pre-NB PLT count <70 × 10(9)/L. Pre-NB tests for prothrombin time (PT) and activated partial thromboplastin time (APTT) were less common and varied among laboring patients (15 [24%] of 62) and patients prior to CD (18 [47%] of 38). Prior to NB, PT and APTT values were within normal limits in all patients. The time intervals between laboratory testing and NB ranged from <2 to >12 hours. The lack of consistency in pre-NB coagulation testing and the variable time intervals between laboratory tests and NB may be due to a lack of consensus among anesthesiologists for determining "safe" hemostatic conditions for NB placement in patients with preeclampsia.

Entities:  

Keywords:  gynecology and obstetrics; hemostasis; neuraxial anesthesia; preeclampsia; thrombocytopenia

Mesh:

Year:  2012        PMID: 22531481     DOI: 10.1177/1076029612441860

Source DB:  PubMed          Journal:  Clin Appl Thromb Hemost        ISSN: 1076-0296            Impact factor:   2.389


  5 in total

1.  Anesthetic practices for patients with preeclampsia or HELLP syndrome: A survey.

Authors:  Betül Başaran; Bilge Çelebioğlu; Ahmet Başaran; Seher Altınel; Leyla Kutlucan; James N Martin
Journal:  J Turk Ger Gynecol Assoc       Date:  2016-09-01

2.  Effect of general anesthesia combined with epidural anesthesia on circulation and stress response of patients undergoing hysterectomy.

Authors:  Yu Liu; Songzhi He; Shuying Zhou
Journal:  Am J Transl Res       Date:  2021-05-15       Impact factor: 4.060

3.  Blood coagulation parameters and platelet indices: changes in normal and preeclamptic pregnancies and predictive values for preeclampsia.

Authors:  Lei Han; Xiaojie Liu; Hongmei Li; Jiaqun Zou; Zhiling Yang; Jian Han; Wei Huang; Lili Yu; Yingru Zheng; Li Li
Journal:  PLoS One       Date:  2014-12-02       Impact factor: 3.240

4.  Association between coagulation function and patients with primary angle closure glaucoma: a 5-year retrospective case-control study.

Authors:  Shengjie Li; Yanting Gao; Mingxi Shao; Binghua Tang; Wenjun Cao; Xinghuai Sun
Journal:  BMJ Open       Date:  2017-11-04       Impact factor: 2.692

5.  Coagulation parameters are associated with the prognosis of immunoglobulin a nephropathy: a retrospective study.

Authors:  Ming Xia; Di Liu; Liang Peng; Yan Li; Haiyang Liu; Lingzhi Wu; Guochun Chen; Yu Liu; Hong Liu
Journal:  BMC Nephrol       Date:  2020-10-27       Impact factor: 2.388

  5 in total

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