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Literature DB >> 22529360

From EPOthilone to EPO: Aa challenge for natural product synthesis.

Zachary Z Brown¹, Tom W Muir.

Abstract

Entities: Chemical Gene

Mesh：

Substances：

Year: 2012 PMID： 22529360 PMCID： PMC3358838 DOI： 10.1073/pnas.1205667109

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

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References

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13 in total

1. Design and chemical synthesis of a homogeneous polymer-modified erythropoiesis protein.

Authors: Gerd G Kochendoerfer; Shiah-Yun Chen; Feng Mao; Sonya Cressman; Stacey Traviglia; Haiyan Shao; Christie L Hunter; Donald W Low; E Neil Cagle; Maia Carnevali; Vincent Gueriguian; Peter J Keogh; Heather Porter; Stephen M Stratton; M Con Wiedeke; Jill Wilken; Jie Tang; Jay J Levy; Les P Miranda; Milan M Crnogorac; Suresh Kalbag; Paolo Botti; Janice Schindler-Horvat; Laura Savatski; John W Adamson; Ada Kung; Stephen B H Kent; James A Bradburne
Journal: Science Date: 2003-02-07 Impact factor: 47.728

2. Chemical synthesis of homogeneous human glycosyl-interferon-β that exhibits potent antitumor activity in vivo.

Authors: Izumi Sakamoto; Katsunari Tezuka; Kazuhiro Fukae; Kazuyuki Ishii; Keisuke Taduru; Masatoshi Maeda; Masaki Ouchi; Kenta Yoshida; Yuri Nambu; Jun Igarashi; Naohiro Hayashi; Takashi Tsuji; Yasuhiro Kajihara
Journal: J Am Chem Soc Date: 2012-03-15 Impact factor: 15.419

3. Free-radical-based, specific desulfurization of cysteine: a powerful advance in the synthesis of polypeptides and glycopolypeptides.

Authors: Qian Wan; Samuel J Danishefsky
Journal: Angew Chem Int Ed Engl Date: 2007 Impact factor: 15.336

4. Semisynthesis of a homogeneous glycoprotein enzyme: ribonuclease C: part 2.

Authors: Christian Piontek; Daniel Varón Silva; Christian Heinlein; Claudia Pöhner; Stefano Mezzato; Petra Ring; Andreas Martin; Franz Xaver Schmid; Carlo Unverzagt
Journal: Angew Chem Int Ed Engl Date: 2009 Impact factor: 15.336

5. Design and synthesis of a homogeneous erythropoietin analogue with two human complex-type sialyloligosaccharides: combined use of chemical and bacterial protein expression methods.

Authors: Kiriko Hirano; Derek Macmillan; Katsunari Tezuka; Takashi Tsuji; Yasuhiro Kajihara
Journal: Angew Chem Int Ed Engl Date: 2009 Impact factor: 15.336

From EPOthilone to EPO: Aa challenge for natural product synthesis.

1. Design and chemical synthesis of a homogeneous polymer-modified erythropoiesis protein.

2. Chemical synthesis of homogeneous human glycosyl-interferon-β that exhibits potent antitumor activity in vivo.

3. Free-radical-based, specific desulfurization of cysteine: a powerful advance in the synthesis of polypeptides and glycopolypeptides.

4. Semisynthesis of a homogeneous glycoprotein enzyme: ribonuclease C: part 2.

5. Design and synthesis of a homogeneous erythropoietin analogue with two human complex-type sialyloligosaccharides: combined use of chemical and bacterial protein expression methods.

6. Role of sugar chains in the expression of the biological activity of human erythropoietin.

7. Probing the stability of nonglycosylated wild-type erythropoietin protein via reiterative alanine ligations.

8. Recent Departures in the Synthesis of Peptides and Glycopeptides.

9. Synthesis of proteins by native chemical ligation.

Review 10. Development and characterization of novel erythropoiesis stimulating protein (NESP).