Literature DB >> 19180621

Semisynthesis of a homogeneous glycoprotein enzyme: ribonuclease C: part 2.

Christian Piontek1, Daniel Varón Silva, Christian Heinlein, Claudia Pöhner, Stefano Mezzato, Petra Ring, Andreas Martin, Franz Xaver Schmid, Carlo Unverzagt.   

Abstract

Active RNase glycoprotein from three pieces: The glycoprotein enzyme ribonuclease C, which contains a complex saccharide N-glycan, was synthesized by sequential native chemical ligation. An optimized ligation and isolation protocol allowed the efficient assembly and refolding of the 124 amino acid enzyme.

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Year:  2009        PMID： 19180621     DOI： 10.1002/anie.200804735

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  21 in total

Review 1.  Emerging technologies for making glycan-defined glycoproteins.

Authors:  Lai-Xi Wang; Joseph V Lomino
Journal:  ACS Chem Biol       Date:  2011-12-14       Impact factor: 5.100

2.  From EPOthilone to EPO: Aa challenge for natural product synthesis.

Authors:  Zachary Z Brown; Tom W Muir
Journal:  Proc Natl Acad Sci U S A       Date:  2012-04-23       Impact factor: 11.205

3.  Total synthesis of the α-subunit of human glycoprotein hormones: toward fully synthetic homogeneous human follicle-stimulating hormone.

Authors:  Baptiste Aussedat; Bernhard Fasching; Eric Johnston; Neeraj Sane; Pavel Nagorny; Samuel J Danishefsky
Journal:  J Am Chem Soc       Date:  2012-02-06       Impact factor: 15.419

4.  Obstacles and solutions for chemical synthesis of syndecan-3 (53-62) glycopeptides with two heparan sulfate chains.

Authors:  Weizhun Yang; Keisuke Yoshida; Bo Yang; Xuefei Huang
Journal:  Carbohydr Res       Date:  2016-10-20       Impact factor: 2.104

Review 5.  Chemoenzymatic Semisynthesis of Proteins.

Authors:  Robert E Thompson; Tom W Muir
Journal:  Chem Rev       Date:  2019-11-27       Impact factor: 60.622

6.  Chemical Synthesis of Phosphorylated Histone H2A at Tyr57 Reveals Insight into the Inhibition Mode of the SAGA Deubiquitinating Module.

Authors:  Muhammad Jbara; Suman Kumar Maity; Michael Morgan; Cynthia Wolberger; Ashraf Brik
Journal:  Angew Chem Int Ed Engl       Date:  2016-03-09       Impact factor: 15.336

7.  A PEGylated photocleavable auxiliary mediates the sequential enzymatic glycosylation and native chemical ligation of peptides.

Authors:  Claudia Bello; Shuo Wang; Lu Meng; Kelley W Moremen; Christian F W Becker
Journal:  Angew Chem Int Ed Engl       Date:  2015-05-15       Impact factor: 15.336

Review 8.  Chemical and chemoenzymatic synthesis of glycoproteins for deciphering functions.

Authors:  Lai-Xi Wang; Mohammed N Amin
Journal:  Chem Biol       Date:  2014-01-16

Review 9.  Chemoenzymatic Methods for the Synthesis of Glycoproteins.

Authors:  Chao Li; Lai-Xi Wang
Journal:  Chem Rev       Date:  2018-08-24       Impact factor: 60.622

Review 10.  The winding pathway to erythropoietin along the chemistry-biology frontier: a success at last.

Authors:  Rebecca M Wilson; Suwei Dong; Ping Wang; Samuel J Danishefsky
Journal:  Angew Chem Int Ed Engl       Date:  2013-06-17       Impact factor: 15.336
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