Jack D Sobel1, Zeev Karpas, Avraham Lorber. 1. Harper University Hospital, Division of Infectious Diseases, Wayne State University School of Medicine, MI 48201, USA. jsobel@med.wayne.edu
Abstract
OBJECTIVE: To compare diagnosis of bacterial vaginosis according to the Amsel criteria with measurement by ion mobility spectrometry (IMS) of the biogenic amines that are present in vaginal discharge fluid. STUDY DESIGN: Duplicate samples of vaginal fluid were collected from 115 unselected and consecutive patients in a vaginitis clinic in Detroit. All samples were evaluated using Amsel criteria and the results were compared with the diagnosis based on the IMS results. RESULTS: The incidence rate of vaginal infections was assessed on the basis of both tests and the frequency of BV was found to be 17.4%. The sensitivity and specificity for bacterial vaginosis diagnosis using IMS determination were 95.5% and 98.9%, respectively, with an accuracy of 94.4%. CONCLUSIONS: The results show that IMS may be used to rapidly diagnose this common vaginal infection with high accuracy.
OBJECTIVE: To compare diagnosis of bacterial vaginosis according to the Amsel criteria with measurement by ion mobility spectrometry (IMS) of the biogenic amines that are present in vaginal discharge fluid. STUDY DESIGN: Duplicate samples of vaginal fluid were collected from 115 unselected and consecutive patients in a vaginitis clinic in Detroit. All samples were evaluated using Amsel criteria and the results were compared with the diagnosis based on the IMS results. RESULTS: The incidence rate of vaginal infections was assessed on the basis of both tests and the frequency of BV was found to be 17.4%. The sensitivity and specificity for bacterial vaginosis diagnosis using IMS determination were 95.5% and 98.9%, respectively, with an accuracy of 94.4%. CONCLUSIONS: The results show that IMS may be used to rapidly diagnose this common vaginal infection with high accuracy.
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